Developmental expression of human tau in Drosophila melanogaster glial cells induces motor deficits and disrupts maintenance of PNS axonal integrity, without affecting synapse formation.
人类 tau 蛋白在果蝇神经胶质细胞中的发育表达会导致运动缺陷,并破坏周围神经系统轴突完整性的维持,但不会影响突触的形成
期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0226380
Scarpelli Enrico M, Trinh Van Y, Tashnim Zarrin, Krans Jacob L, Keller Lani C, Colodner Kenneth J