Oncogenic JAK2(V617F) causes PD-L1 expression, mediating immune escape in myeloproliferative neoplasms
致癌性JAK2(V617F)导致PD-L1表达，介导骨髓增生性肿瘤的免疫逃逸。
期刊:Science Translational Medicine
影响因子:14.6
doi:10.1126/scitranslmed.aam7729
Prestipino, Alessandro; Emhardt, Alica J; Aumann, Konrad; O'Sullivan, David; Gorantla, Sivahari P; Duquesne, Sandra; Melchinger, Wolfgang; Braun, Lukas; Vuckovic, Slavica; Boerries, Melanie; Busch, Hauke; Halbach, Sebastian; Pennisi, Sandra; Poggio, Teresa; Apostolova, Petya; Veratti, Pia; Hettich, Michael; Niedermann, Gabriele; Bartholomä, Mark; Shoumariyeh, Khalid; Jutzi, Jonas S; Wehrle, Julius; Dierks, Christine; Becker, Heiko; Schmitt-Graeff, Annette; Follo, Marie; Pfeifer, Dietmar; Rohr, Jan; Fuchs, Sebastian; Ehl, Stephan; Hartl, Frederike A; Minguet, Susana; Miething, Cornelius; Heidel, Florian H; Kröger, Nicolaus; Triviai, Ioanna; Brummer, Tilman; Finke, Jürgen; Illert, Anna L; Ruggiero, Eliana; Bonini, Chiara; Duyster, Justus; Pahl, Heike L; Lane, Steven W; Hill, Geoffrey R; Blazar, Bruce R; von Bubnoff, Nikolas; Pearce, Erika L; Zeiser, Robert
肿瘤
肿瘤免疫
JAK/STAT
JAK2
PD-L1
免疫/内分泌
