日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Towards Personalized Lymphodepletion: A Population Pharmacokinetic Fludarabine Model in Patients Receiving CAR T-Cell Therapy

迈向个体化淋巴清除:接受 CAR-T 细胞疗法患者的氟达拉滨群体药代动力学模型

Varela-González-Aller, Javier; Sánchez-Salinas, Mario Andrés; Troconiz, Iñaki; Iacoboni, Gloria; Alonso-Martínez, Carla; Carreras-Soler, Maria-Josep; Carpio, Cecilia; Farriols-Danes, Anna; Guerra-González, María; Rivas-Delgado, Alfredo; Rivera Sanchez, Lucas; Feijoo, Samantha; Valdivia, Carolina; Barba, Pere; Miarons, Marta

Development and Application of Physiologically-Based Pharmacokinetic Model to Predict Systemic and Organ Exposure of Colorectal Cancer Drugs

基于生理的药代动力学模型在预测结直肠癌药物全身和器官暴露量中的应用

Peribañez-Dominguez, Sara; Parra-Guillen, Zinnia; Troconiz, Iñaki F

Dynamics of thrombin generation: Filling the gap between the system pharmacology theory and clinical practice in clinical pharmacology and therapeutics

凝血酶生成动力学:弥合系统药理学理论与临床药理学和治疗学实践之间的差距

Ruiz, Leire; Jaramillo, Sebastian; Calvo, Andrea; Torrente, M A; Tassies, Dolors; Reverter, J C; Blasi, Annabel; Troconiz, Iñaki

Quantitative Approach to Explore Regulatory T Cell Activity in Immuno-Oncology

定量方法探索免疫肿瘤学中的调节性T细胞活性

Serrano, Alejandro; Zalba, Sara; Lasarte, Juan Jose; Troconiz, Iñaki F; Riva, Natalia; Garrido, Maria J

How to use meropenem in pediatric patients undergoing CKRT? Integrated meropenem pharmacokinetic model for critically ill children

如何在接受持续肾脏替代治疗(CKRT)的儿科患者中使用美罗培南?危重儿童美罗培南的综合药代动力学模型

Butragueño-Laiseca, Laura; Troconiz, Iñaki F; Grau, Santiago; Campillo, Nuria; Padilla, Belén; Fernández, Sarah Nicole; Slöcker, María; Herrera, Laura; Santiago, María José

A physiologically based pharmacokinetic model for V937 oncolytic virus in mice

基于生理学的小鼠V937溶瘤病毒药代动力学模型

Peribañez-Dominguez, Sara; Parra-Guillen, Zinnia P; Freshwater, Tomoko; Troconiz, Iñaki F

Pharmacological Probes to Validate Biomarkers for Analgesic Drug Development

药理学探针用于验证镇痛药物研发中的生物标志物

van Niel, Johannes; Bloms-Funke, Petra; Caspani, Ombretta; Cendros, Jose Maria; Garcia-Larrea, Luis; Truini, Andrea; Tracey, Irene; Chapman, Sonya C; Marco-Ariño, Nicolás; Troconiz, Iñaki F; Phillips, Keith; Finnerup, Nanna Brix; Mouraux, André; Treede, Rolf-Detlef

Semimechanistic models to relate noxious stimulation, movement, and pupillary dilation responses in the presence of opioids

半机械模型用于描述在阿片类药物存在下,有害刺激、运动和瞳孔扩张反应之间的关系

Marco-Ariño, Nicolás; Vide, Sergio; Agustí, Mercè; Chen, Andrew; Jaramillo, Sebastián; Irurzun-Arana, Itziar; Pacheco, Adrià; Gonzalez, Carmen; Jensen, Erik W; Capsi-Morales, Patricia; Valencia, José F; Troconiz, Iñaki F; Gambus, Pedro L; Larson, Merlin D

IMI2-PainCare-BioPain-RCT1: study protocol for a randomized, double-blind, placebo-controlled, crossover, multi-center trial in healthy subjects to investigate the effects of lacosamide, pregabalin, and tapentadol on biomarkers of pain processing observed by peripheral nerve excitability testing (NET)

IMI2-PainCare-BioPain-RCT1:一项随机、双盲、安慰剂对照、交叉、多中心试验的研究方案,旨在研究拉考沙胺、普瑞巴林和他喷他多对通过周围神经兴奋性测试 (NET) 观察到的疼痛处理生物标志物的影响,受试者为健康人群。

Nochi, Zahra; Pia, Hossein; Bloms-Funke, Petra; Boesl, Irmgard; Caspani, Ombretta; Chapman, Sonya C; Fardo, Francesca; Genser, Bernd; Goetz, Marcus; Kostenko, Anna V; Leone, Caterina; Li, Thomas; Mouraux, André; Pelz, Bernhard; Pogatzki-Zahn, Esther; Schilder, Andreas; Schnetter, Erik; Schubart, Karin; Stouffs, Alexandre; Tracey, Irene; Troconiz, Iñaki F; Truini, Andrea; Van Niel, Johannes; Vela, Jose Miguel; Vincent, Katy; Vollert, Jan; Wanigasekera, Vishvarani; Wittayer, Matthias; Tankisi, Hatice; Finnerup, Nanna B; Phillips, Keith G; Treede, Rolf-Detlef

IMI2-PainCare-BioPain-RCT2 protocol: a randomized, double-blind, placebo-controlled, crossover, multicenter trial in healthy subjects to investigate the effects of lacosamide, pregabalin, and tapentadol on biomarkers of pain processing observed by non-invasive neurophysiological measurements of human spinal cord and brainstem activity

IMI2-PainCare-BioPain-RCT2方案:一项在健康受试者中进行的随机、双盲、安慰剂对照、交叉、多中心试验,旨在研究拉考沙胺、普瑞巴林和他喷他多对疼痛处理生物标志物的影响,这些生物标志物通过对人类脊髓和脑干活动的非侵入性神经生理测量来观察。

Leone, Caterina; Di Stefano, Giulia; Di Pietro, Giuseppe; Bloms-Funke, Petra; Boesl, Irmgard; Caspani, Ombretta; Chapman, Sonya C; Finnerup, Nanna Brix; Garcia-Larrea, Luis; Li, Tom; Goetz, Marcus; Mouraux, André; Pelz, Bernhard; Pogatzki-Zahn, Esther; Schilder, Andreas; Schnetter, Erik; Schubart, Karin; Tracey, Irene; Troconiz, Inaki F; Van Niel, Hans; Hernandez, Jose Miguel Vela; Vincent, Katy; Vollert, Jan; Wanigasekera, Vishvarani; Wittayer, Matthias; Phillips, Keith G; Truini, Andrea; Treede, Rolf-Detlef