日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cis-aconitate therapy protects against influenza mortality by dual targeting of viral polymerase and ERK/AKT/NF-κB signaling

顺式乌头酸疗法通过双重靶向病毒聚合酶和ERK/AKT/NF-κB信号通路来降低流感死亡率

Adeline Cezard,Déborah Brea-Diakite,Virginie Vasseur,Alan Wacquiez,Loic Gonzalez,Ronan Le Goffic,Bruno Da Costa,Ambre Tinard,Delphine Fouquenet,Séverine Heumel,Arnaud Machelart,Eik Hoffmann,Priscille Brodin,François Trottein,Cyrille Mathieu,Lola Canus,Florentine Jacolin,Pierre-Olivier Vidalain,Laure Perrin-Cocon,Vincent Lotteau,Julien Burlaud-Gaillard,Dominique Tertigas,Michael G Surette,Antoine Legras,Damien Sizaret,Thomas Baranek,Christophe Paget,Antoine Guillon,Mustapha Si-Tahar

Senolytic Treatment Reduces Acute and Chronic Lung Inflammation in an Aged Mouse Model of Influenza.

衰老细胞清除疗法可减轻老年流感小鼠模型中的急性和慢性肺部炎症。

Delval Lou, Creskey Marybeth, Valentin Clara, Bordas Clément, Raviola Stephano, Lipskaia Larissa, Heumel Séverine, Deruyter Lucie, Sencio Valentin, Wolowczuk Isabelle, Bernard David, Adnot Serge, Gosset Philippe, Zhang Xu, Trottein François

Integrative metagenomics and metabolomics reveal age-associated gut microbiota and metabolite alterations in a hamster model of COVID-19

整合宏基因组学和代谢组学揭示了新冠肺炎仓鼠模型中与年龄相关的肠道菌群和代谢物变化

Brito Rodrigues, Patrícia; de Rezende Rodovalho, Vinícius; Sencio, Valentin; Benech, Nicolas; Creskey, Marybeth; Silva Angulo, Fabiola; Delval, Lou; Robil, Cyril; Gosset, Philippe; Machelart, Arnaud; Haas, Joel; Descat, Amandine; Goosens, Jean François; Beury, Delphine; Maurier, Florence; Hot, David; Wolowczuk, Isabelle; Sokol, Harry; Zhang, Xu; Ramirez Vinolo, Marco Aurélio; Trottein, François

Metaproteomics reveals age-specific alterations of gut microbiome in hamsters with SARS-CoV-2 infection

宏蛋白质组学揭示了感染SARS-CoV-2病毒的仓鼠肠道微生物群的年龄特异性改变

Creskey, Marybeth; Silva Angulo, Fabiola; Wu, Qing; Tamming, Levi; Fekete, Emily E F; Cheng, Kai; Ning, Zhibin; Wang, Angela; Brito Rodrigues, Patrícia; de Rezende Rodovalho, Vinícius; Ramirez Vinolo, Marco Aurélio; Figeys, Daniel; Li, Xuguang; Trottein, Francois; Zhang, Xu

Gut microbiota alterations are linked to COVID-19 severity in North African and European populations

肠道菌群改变与北非和欧洲人群新冠肺炎的严重程度相关

Bredon, Marius; Hausfater, Pierre; Khalki, Loubna; Tijani, Youssef; Cheikh, Amine; Brot, Loic; Creusot, Laura; Rolhion, Nathalie; Trottein, Francois; Lambeau, Gérard; Georgin-Lavialle, Sophie; Bleibtreu, Alexandre; Baudel, Jean-Luc; Lefèvre, Antoine; Emond, Patrick; Tubach, Florence; Simon-Tillaux, Noémie; Simon, Tabassome; Gorochov, Guy; Zaid, Younes; Sokol, Harry

Virus-Induced Cellular Senescence Causes Pulmonary Sequelae Post-Influenza Infection.

病毒诱导的细胞衰老导致流感感染后肺部后遗症

Lipskaia Larissa, Delval Lou, Sencio Valentin, Born Emmanuelle, Heumel Séverine, Houssaini Amal, Valentin Clara, Raviola Stefano, Deruyter Lucie, Angulo Fabiola Silva, Gros Vincent, Marcos Elisabeth, Abid Shariq, Goekyildirim Mira, Contreras Vanessa, Flaman Jean Michel, Le Grand Roger, Le Goffic Ronan, Bernard David, Adnot Serge, Trottein François

Impact of aging on gut-lung-adipose tissue interactions and lipid metabolism during influenza infection in mice

衰老对小鼠流感感染期间肠-肺-脂肪组织相互作用和脂质代谢的影响

Gemma Bogard ,Kassem Makki ,Patricia Brito-Rodrigues ,Jian Tan ,Olivier Molendi-Coste ,Johanna Barthelemy ,Amandine Descat ,Fabrice Bouilloux ,Cécile Lecoeur ,Corinne Grangette ,Cyril Robil ,Jean-François Goossens ,Philippe Gosset ,Laurence Macia ,François Trottein ,Isabelle Wolowczuk

Anti-Tumor Efficacy of a Mesothelin-Based Nanovaccine in a KPC Orthotopic Mouse Model of Pancreatic Cancer.

基于间皮素的纳米疫苗在KPC原位胰腺癌小鼠模型中的抗肿瘤疗效

Ferrari Daniele P, Çobanoglu Özmen, Sayedipour Sana, Luna Omar, Ferkel Sonia A M, Agorku David, Perez Yomkippur, Cruz Luis J, Albericio Fernando, Trottein François, Alves Frauke, Markus Marietta Andrea, Ramos-Gomes Fernanda

IFN-γ primes bone marrow neutrophils to acquire regulatory functions in severe viral respiratory infections

IFN-γ 可启动骨髓中性粒细胞,使其在严重病毒性呼吸道感染中获得调节功能。

Creusat, Florent; Jouan, Youenn; Gonzalez, Loïc; Barsac, Emilie; Ilango, Guy; Lemoine, Roxane; Soulard, Daphnée; Hankard, Antoine; Boisseau, Chloé; Guillon, Antoine; Lin, Qiaochu; de Amat Herbozo, Carolina; Sencio, Valentin; Winter, Nathalie; Sizaret, Damien; Trottein, François; Si-Tahar, Mustapha; Briard, Benoit; Mallevaey, Thierry; Faveeuw, Christelle; Baranek, Thomas; Paget, Christophe

Role of astrocyte senescence regulated by the non- canonical autophagy in the neuroinflammation associated to cerebral malaria

非典型自噬调控星形胶质细胞衰老在脑型疟疾相关神经炎症中的作用

Fatima Hellani, Inès Leleu, Nasreddine Saidi, Nathalie Martin, Cécile Lecoeur, Elisabeth Werkmeister, David Koffi, François Trottein, Hélène Yapo-Etté, Bidyut Das, Corinne Abbadie, Sylviane Pied