日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

An inflammatory and quiescent HSC subpopulation expands with age in humans.

在人类中,炎症性和静止性造血干细胞亚群会随着年龄的增长而扩增。

Safina Ksenia R, Salik Basit, Kotliar Dylan, Curtis Michelle, Good Jonathan D, Weng Chen, David Shawn, Raychaudhuri Soumya, Kreso Antonia, Trowbridge Jennifer J, Sankaran Vijay G, van Galen Peter

Metallothionein 1 mediates growth and survival of Dnmt3a;Npm1-mutant acute myeloid leukemia

金属硫蛋白 1 介导 Dnmt3a;Npm1 突变型急性髓系白血病的生长和存活

Colom Díaz, Patricia A; Mistry, Jayna J; Young, Kira A; Chou, Chih-Hsing; Boyer, Nathan; Levine, Ross L; Salomonis, Nathan; Grimes, H Leighton; Trowbridge, Jennifer J

Functional equivalence of γ- and x-ray irradiation for long-term peripheral blood chimerism and acute myeloid leukemia transplant outcomes in mice

γ射线和X射线照射对小鼠长期外周血嵌合体和急性髓系白血病移植结果的功能等效性

David, Shawn; Nye, Griffin J; Eudy, Elizabeth; Bolcun-Filas, Ewelina; Trowbridge, Jennifer J; Young, Kira A

TET2-Mutant Clonal Hematopoiesis Promotes Heart Failure With Preserved Ejection Fraction

TET2突变克隆性造血促进射血分数保留型心力衰竭

Pandey, Ambarish; Thomas, Toby; Ji, Yuanyuan; Kroger, Benjamin; Carlsgaard, Peter; Irion, Camila I; Kalkan, Fatma; Segar, Matthew; Subramanian, Vinayak; Bayés-Genís, Antoni; Son, Albert; Young, Kira A; Trowbridge, Jennifer J; Premnath, Naveen; Jiang, Nan; Daou, Daniel; Hu, Wenhuo; Ware, Sarah A; Tong, Dan; Chung, Stephen S

Clonal hematopoiesis in myeloid malignancies and solid tumors

髓系恶性肿瘤和实体瘤中的克隆性造血

Cai, Xiurong; Bowman, Robert L; Trowbridge, Jennifer J

Inflammatory stromal and T cells mediate human bone marrow niche remodeling in clonal hematopoiesis and myelodysplasia

炎症性基质细胞和T细胞介导克隆性造血和骨髓增生异常综合征中人类骨髓微环境的重塑

Prummel, Karin D; Woods, Kevin; Kholmatov, Maksim; Schmitt, Eric C; Vlachou, Evi P; Labyadh, Mayssa; Wehner, Rebekka; Poschmann, Gereon; Stühler, Kai; Winter, Susann; Oelschlaegel, Uta; Wobus, Manja; Schwartz, Logan S; Moura, Pedro L; Hellström-Lindberg, Eva; Rajalingam, Krishnaraj; Theobald, Matthias; Trowbridge, Jennifer J; Carron, Clémence; Jaffredo, Thierry; Schmitz, Marc; Platzbecker, Uwe; Zaugg, Judith B; Guezguez, Borhane

Functional Equivalence of Gamma- and X-Ray Irradiation for Long-Term Hematopoietic and AML Transplant Outcomes in Mice

γ射线和X射线照射对小鼠长期造血干细胞移植和急性髓系白血病移植结果的功能等效性

David, Shawn; Nye, Griffin J; Bolcun-Filas, Ewelina; Trowbridge, Jennifer J; Young, Kira A

Variation in mesenchymal KITL/SCF and IGF1 expression in middle age underlies steady-state hematopoietic stem cell aging.

中年时期间充质 KITL/SCF 和 IGF1 表达的变化是造血干细胞衰老的稳态基础

Young Kira A, Telpoukhovskaia Maria A, Hofmann Johanna, Mistry Jayna J, Kokkaliaris Konstantinos D, Trowbridge Jennifer J

Transcriptional and functional consequences of Oncostatin M signaling on young Dnmt3a-mutant hematopoietic stem cells

Oncostatin M 信号对年轻的 Dnmt3a 突变造血干细胞的转录和功能影响

Schwartz, Logan S; Young, Kira A; Stearns, Timothy M; Boyer, Nathan; Mujica, Kristina D; Trowbridge, Jennifer J

Inflammatory Mesenchymal Stromal Cells and IFN-responsive T cells are key mediators of human bone marrow niche remodeling in CHIP and MDS

炎症性间充质基质细胞和干扰素反应性T细胞是CHIP和MDS中人类骨髓微环境重塑的关键介质。

Prummel, Karin D; Woods, Kevin; Kholmatov, Maksim; Schmitt, Eric C; Vlachou, Evi P; Poschmann, Gereon; Stühler, Kai; Wehner, Rebekka; Schmitz, Marc; Winter, Susann; Oelschlaegel, Uta; Schwartz, Logan S; Moura, Pedro L; Hellström-Lindberg, Eva; Theobald, Matthias; Trowbridge, Jennifer J; Platzbecker, Uwe; Zaugg, Judith B; Guezguez, Borhane