日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Heterozygous variants in the teashirt zinc finger homeobox 3 (TSHZ3) gene in human congenital anomalies of the kidney and urinary tract.

人类肾脏和泌尿道先天性异常中茶衫锌指同源框 3 (TSHZ3) 基因的杂合变异

Kesdiren Esra, Martens Helge, Brand Frank, Werfel Lina, Wedekind Lukas, Trowe Mark-Oliver, Schmitz Jessica, Hennies Imke, Geffers Robert, Gucev Zoran, Seeman Tomáš, Schmidt Sonja, Tasic Velibor, Fasano Laurent, Bräsen Jan H, Kispert Andreas, Christians Anne, Haffner Dieter, Weber Ruthild G

Interplay of SHH, WNT and BMP4 signaling regulates the development of the lamina propria in the murine ureter

SHH、WNT 和 BMP4 信号通路的相互作用调控小鼠输尿管固有层的发育

Philipp Straube ,Anja Beckers ,Ulrich W H Jany ,Florian Bergmann ,Timo H-W Lüdtke ,Carsten Rudat ,Mark-Oliver Trowe ,Imke Peters ,Maximilian G Klopf ,Tamrat M Mamo ,Andreas Kispert

PPARG contributes to urothelial integrity in the murine ureter by activating the expression of Shh and superficial cell-specific genes.

PPARG 通过激活 Shh 和表面细胞特异性基因的表达,促进小鼠输尿管尿路上皮的完整性

Rudat Carsten, Straube Philipp, Hegermann Jan, Trowe Mark-Oliver, Thiesler Hauke, Hildebrandt Herbert, Witt Lisa, Kispert Andreas

Phase I Study of GS-3583, an FMS-like Tyrosine Kinase 3 Agonist Fc Fusion Protein, in Patients with Advanced Solid Tumors

GS-3583(一种FMS样酪氨酸激酶3激动剂Fc融合蛋白)在晚期实体瘤患者中的I期研究

Tolcher, Anthony W; Brody, Joshua D; Rajakumaraswamy, Nishanthan; Kuhne, Michelle; Trowe, Torsten; Dauki, Anees M; Pai, Shantheri; Han, Ling; Lin, Kai-Wen; Petrarca, Michael; Kummar, Shivaani

Pharmacokinetics, pharmacodynamics, and safety of GS-3583, a FLT3 agonist Fc fusion protein, from single-ascending-dose phase I study in healthy participants

GS-3583(一种FLT3激动剂Fc融合蛋白)在健康受试者中单次递增剂量I期研究中的药代动力学、药效学和安全性

Dauki, Anees M; Rajakumaraswamy, Nishanthan; Trowe, Torsten; Weng, Winnie; Lin, Kai-Wen; Elboudjwarej, Emon; Qin, Ann Ran-Ran; Schwabe, Christian; Kuhne, Michelle R; Othman, Ahmed A

Intrahepatic quantification of HBV antigens in chronic hepatitis B reveals heterogeneity and treatment-mediated reductions in HBV core-positive cells

慢性乙型肝炎患者肝内HBV抗原定量分析揭示了其异质性,并发现治疗可导致HBV核心阳性细胞减少。

Aggarwal, Abhishek; Odorizzi, Pamela M; Brodbeck, Jens; van Buuren, Nicholas; Moon, Christina; Chang, Silvia; Adona, MaryVic; Suthram, Silpa; Suri, Vithika; Trowe, Torsten; Turner, Scott; Marcellin, Patrick; Buti, Maria; Gaggar, Anuj; Fletcher, Simon P; Diehl, Lauri; Feierbach, Becket; Balsitis, Scott

SMG1, a nonsense-mediated mRNA decay (NMD) regulator, as a candidate therapeutic target in multiple myeloma

SMG1 是一种无义介导的 mRNA 衰变 (NMD) 调节剂,可作为多发性骨髓瘤的候选治疗靶点

Alexander C Leeksma, Ingrid A M Derks, Brett Garrick, Aldo Jongejan, Martino Colombo, Timon Bloedjes, Torsten Trowe, Jim C Leisten, Michelle Howarth, Mehnaz Malek, Deborah S Mortensen, Kate Blease, Mathew C Groza, Rama Krishna Narla, Remco Loos, Marie-José Kersten, Perry D Moerland, Jeroen E J Guike

Heterozygous variants in the DVL2 interaction region of DACT1 cause CAKUT and features of Townes-Brocks syndrome 2

DACT1 的 DVL2 相互作用区域中的杂合变异导致 CAKUT 和 Townes-Brocks 综合征 2 的特征

Anne Christians, Esra Kesdiren, Imke Hennies, Alejandro Hofmann, Mark-Oliver Trowe, Frank Brand, Helge Martens, Ann Christin Gjerstad, Zoran Gucev, Matthias Zirngibl, Robert Geffers, Tomáš Seeman, Heiko Billing, Anna Bjerre, Velibor Tasic, Andreas Kispert, Benno Ure, Dieter Haffner, Jens Dingemann, 

TBX2 specifies and maintains inner hair and supporting cell fate in the Organ of Corti

TBX2决定并维持科尔蒂氏器内毛细胞和支持细胞的命运。

Marina Kaiser ,Timo H Lüdtke ,Lena Deuper ,Carsten Rudat ,Vincent M Christoffels ,Andreas Kispert ,Mark-Oliver Trowe

GATA6 is a crucial factor for Myocd expression in the visceral smooth muscle cell differentiation program of the murine ureter

GATA6是小鼠输尿管内脏平滑肌细胞分化过程中Myocd表达的关键因子。

Jennifer Kurz ,Anna-Carina Weiss ,Timo H-W Lüdtke ,Lena Deuper ,Mark-Oliver Trowe ,Hauke Thiesler ,Herbert Hildebrandt ,Joerg Heineke ,Stephen A Duncan ,Andreas Kispert