Discovery of a novel class of dimeric Smac mimetics as potent IAP antagonists resulting in a clinical candidate for the treatment of cancer (AZD5582)
发现一类新型二聚体 Smac 类似物作为有效的 IAP 拮抗剂，从而成为治疗癌症的临床候选药物（AZD5582）
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/jm401075x
Edward J Hennessy, Ammar Adam, Brian M Aquila, Lillian M Castriotta, Donald Cook, Maureen Hattersley, Alexander W Hird, Christopher Huntington, Victor M Kamhi, Naomi M Laing, Danyang Li, Terry MacIntyre, Charles A Omer, Vibha Oza, Troy Patterson, Galina Repik, Michael T Rooney, Jamal C Saeh, Li Sha,
