日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The TLR7 agonist vesatolimod does not measurably induce SIV expression in macaques receiving combination antiretroviral therapy initiated during chronic infection

TLR7激动剂vesatolimod在接受慢性感染期间开始的联合抗逆转录病毒疗法的猕猴中,不能显著诱导SIV表达。

Swanstrom, Adrienne E; Oswald, Kelli; Fast, Randy; Shoemaker, Rebecca; Thomas, James A; Pyle, Cathi; Hull, Michael; Bosche, William J; Li, Yuan; Breed, Matthew W; Kramer, Joshua A; Donohue, Duncan; Trubey, Charles M; Deleage, Claire; Geleziunas, Romas; Lifson, Jeffrey D; Del Prete, Gregory Q

Modifications to rhesus macaque TCR constant regions improve TCR cell surface expression

对恒河猴T细胞受体恒定区的修饰可改善T细胞受体的细胞表面表达。

Coren, Lori V; Trivett, Matthew T; Welker, Jorden L; Thomas, James A; Gorelick, Robert J; Kose, Emek; Immonen, Taina T; Czarra, Kelli; Fennessey, Christine M; Trubey, Charles M; Lifson, Jeffrey D; Swanstrom, Adrienne E

TCR triggering transcriptionally downregulates CCR5 expression on rhesus macaque CD4(+) T-cells with no measurable effect on susceptibility to SIV infection.

TCR 触发转录下调恒河猴 CD4(+) T 细胞上的 CCR5 表达,但对 SIV 感染的易感性没有可测量的影响

Minang Jacob T, Trivett Matthew T, Barsov Eugene V, Del Prete Gregory Q, Trubey Charles M, Thomas James A, Gorelick Robert J, Piatak Michael Jr, Ott David E, Ohlen Claes

3D visualization of HIV transfer at the virological synapse between dendritic cells and T cells.

在树突状细胞和 T 细胞之间的病毒突触处,HIV 转移的 3D 可视化

Felts Richard L, Narayan Kedar, Estes Jacob D, Shi Dan, Trubey Charles M, Fu Jing, Hartnell Lisa M, Ruthel Gordon T, Schneider Douglas K, Nagashima Kunio, Bess Julian W Jr, Bavari Sina, Lowekamp Bradley C, Bliss Donald, Lifson Jeffrey D, Subramaniam Sriram

Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge

效应记忆T细胞反应与保护恒河猴免受黏膜猴免疫缺陷病毒攻击有关。

Hansen, Scott G; Vieville, Cassandra; Whizin, Nathan; Coyne-Johnson, Lia; Siess, Don C; Drummond, Derek D; Legasse, Alfred W; Axthelm, Michael K; Oswald, Kelli; Trubey, Charles M; Piatak, Michael Jr; Lifson, Jeffrey D; Nelson, Jay A; Jarvis, Michael A; Picker, Louis J

Quantitation of HLA class II protein incorporated into human immunodeficiency type 1 virions purified by anti-CD45 immunoaffinity depletion of microvesicles

通过抗CD45免疫亲和力去除微囊泡纯化的1型人类免疫缺陷病毒颗粒中掺入的HLA II类蛋白的定量分析

Trubey, Charles M; Chertova, Elena; Coren, Lori V; Hilburn, Joanne M; Hixson, Catherine V; Nagashima, Kunio; Lifson, Jeffrey D; Ott, David E