日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

SER-109, an Investigational Microbiome Drug to Reduce Recurrence After Clostridioides difficile Infection: Lessons Learned From a Phase 2 Trial

SER-109,一种用于降低艰难梭菌感染复发率的在研微生物组药物:从二期临床试验中汲取的经验教训

McGovern, Barbara H; Ford, Christopher B; Henn, Matthew R; Pardi, Darrell S; Khanna, Sahil; Hohmann, Elizabeth L; O'Brien, Edward J; Desjardins, Christopher A; Bernardo, Patricia; Wortman, Jennifer R; Lombardo, Mary-Jane; Litcofsky, Kevin D; Winkler, Jonathan A; McChalicher, Christopher W J; Li, Sunny S; Tomlinson, Amelia D; Nandakumar, Madhumitha; Cook, David N; Pomerantz, Roger J; Auninš, John G; Trucksis, Michele

Gastrointestinal Tract Microbiome Dynamics Following Treatment with SER-109, an Investigational Oral Microbiome Therapeutic to Reduce the Recurrence of Clostridium difficile Infection (CDI)

使用 SER-109(一种用于减少艰难梭菌感染 (CDI) 复发的在研口服微生物组疗法)治疗后胃肠道微生物组动态变化

Zhao, Teng; Li, Bo-Qi; Gao, He-Ting; Xing, Dan; Li, Man-Jin; Dang, Yun-Qi; Zhang, Heng-Duan; Zhao, Yue-E; Liu, Zhu; Li, Chun-Xiao; Henn, Matthew; Ford, Christopher; O’Brien, Edward; Wortman, Jennifer; Simmons, Sheri; Diao, Liyang; Litcofsky, Kevin; Bernardo, Patricia; Aunins, John; Cook, David; Trucksis, Michele

Preclinical Pharmacokinetics and Pharmacodynamic Target of SCY-078, a First-in-Class Orally Active Antifungal Glucan Synthesis Inhibitor, in Murine Models of Disseminated Candidiasis

SCY-078(一种首创的口服活性抗真菌葡聚糖合成抑制剂)在播散性念珠菌病小鼠模型中的临床前药代动力学和药效学靶点研究

Wring, Stephen A; Randolph, Ryan; Park, SeongHee; Abruzzo, George; Chen, Qing; Flattery, Amy; Garrett, Graig; Peel, Michael; Outcalt, Russell; Powell, Kendall; Trucksis, Michelle; Angulo, David; Borroto-Esoda, Katyna

A single supratherapeutic dose of ridaforolimus does not prolong the QTc interval in patients with advanced cancer

单次超治疗剂量的利达福罗莫司不会延长晚期癌症患者的QTc间期。

Lush, Richard M; Patnaik, Amita; Sullivan, Daniel; Papadopoulos, Kyriakos P; Trucksis, Michele; McCrea, Jacqueline; Cerchio, Kristine; Li, Xiaodong; Stroh, Mark; Selverian, Diana; Orford, Keith; Ebbinghaus, Scot; Agrawal, Nancy; Iwamoto, Marian; Wagner, John A; Tolcher, Anthony

The Vibrio cholerae genome contains two unique circular chromosomes

霍乱弧菌基因组包含两条独特的环状染色体。

Trucksis, M; Michalski, J; Deng, Y K; Kaper, J B

Goldfish, Carassius auratus, a novel animal model for the study of Mycobacterium marinum pathogenesis

金鱼,鲫鱼,一种用于研究海洋分枝杆菌发病机制的新型动物模型

Talaat, A M; Reimschuessel, R; Wasserman, S S; Trucksis, M

Identification and localization of a gene that specifies production of Escherichia coli DNA topoisomerase I

鉴定和定位编码大肠杆菌DNA拓扑异构酶I产生的基因

Trucksis, M; Depew, R E

Salmonella typhimurium mutants with reduced levels of transfer ribonucleic acid-inhibitable endodeoxyribonucleolytic activity

沙门氏菌突变体中转移核糖核酸可抑制的内切脱氧核糖核酸酶活性降低

Zabel, D J; Trucksis, M; Depew, R E