日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Deep learning-based assessment of PD-L1 expression in NSCLC predicts outcome for patients treated with anti-PD-1 immunotherapy

基于深度学习的非小细胞肺癌PD-L1表达评估可预测接受抗PD-1免疫疗法治疗患者的预后

Peroz, Morgane; Roussot, Nicolas; Ilie, Alis; Rageot, David; Derangere, Valentin; Truntzer, Caroline; Ghiringhelli, François

Safety and efficacy of trifluridine/tipiracil +/- bevacizumab plus XB2001 (anti-IL-1α antibody): a single-center phase 1 trial

三氟尿苷/替吡嘧啶联合或不联合贝伐珠单抗加XB2001(抗IL-1α抗体)的安全性和有效性:一项单中心1期试验

Marion Thibaudin ,Nicolas Roussot ,Chloé Burlot ,Antonin Schmitt ,Julie Vincent ,Zoé Tharin ,Leila Bengrine ,Hélène Bellio ,Aurélie Bertaut ,Léa Hampe ,Susy Daumoine ,Emilie Rederstorff ,Morgane Peroz ,Titouan Huppe ,Valentin Derangère ,David Rageot ,John Simard ,Caroline Truntzer ,Jean David Fumet ,Francois Ghiringhelli

Cancer cell-derived IL-1β reverses chemo-immunotherapy resistance in non-small cell lung cancer

癌细胞来源的IL-1β可逆转非小细胞肺癌的化疗-免疫治疗耐药性

Anaïs Perrichet ,Julie Lecuelle ,Emeric Limagne ,Marie Thiefin ,Hélène Bellio ,Pierre Jacob ,Romain Aucagne ,Aziza Aznague ,Pauline Russo ,Flavie Gaucher ,Nicolas Roussot ,Xingping Yang ,Thibault Vernet ,Lisa Nuttin ,Alis Ilie ,David Rageot ,Valentin Derangère ,Titouan Huppe ,Alfred Zippelius ,Bertrand Routy ,Caroline Truntzer ,Fanny Chalmin ,François Ghiringhelli # ,Cédric Rébé #

Co-targeting TGF-β and PD-L1 sensitizes triple-negative breast cancer to experimental immunogenic cisplatin-eribulin chemotherapy doublet.

共同靶向 TGF-β 和 PD-L1 可使三阴性乳腺癌对实验性免疫原性顺铂-艾立布林双药化疗敏感

Kalfeist Laura, Ledys Fanny, Petit Stacy, Poirrier Cyriane, Kada Mohammed Samia, Galland Loïck, Derangère Valentin, Ilie Alis, Rageot David, Aucagne Romain, Bellaye Pierre-Simon, Truntzer Caroline, Thibaudin Marion, Rialland Mickaël, Ghiringhelli François, Limagne Emeric, Ladoire Sylvain

Deep learning uncovers histological patterns of YAP1/TEAD activity related to disease aggressiveness in cancer patients

深度学习揭示了与癌症患者疾病侵袭性相关的YAP1/TEAD活性组织学模式

Schmauch, Benoit; Cabeli, Vincent; Domingues, Omar Darwiche; Le Douget, Jean-Eudes; Hardy, Alexandra; Belbahri, Reda; Maussion, Charles; Romagnoni, Alberto; Eckstein, Markus; Fuchs, Florian; Swalduz, Aurélie; Lantuejoul, Sylvie; Crochet, Hugo; Ghiringhelli, François; Derangere, Valentin; Truntzer, Caroline; Pass, Harvey; Moreira, Andre L; Chiriboga, Luis; Zheng, Yuanning; Ozawa, Michael; Howitt, Brooke E; Gevaert, Olivier; Girard, Nicolas; Rexhepaj, Elton; Valtingojer, Iris; Debussche, Laurent; de Rinaldis, Emanuele; Nestle, Frank; Spanakis, Emmanuel; Fantin, Valeria R; Durand, Eric Y; Classe, Marion; Von Loga, Katharina; Pronier, Elodie; Cesaroni, Matteo

The DAV132 colon-targeted adsorbent does not interfere with plasma concentrations of antibiotics but prevents antibiotic-related dysbiosis: a randomized phase I trial in healthy volunteers

DAV132结肠靶向吸附剂不干扰抗生素的血浆浓度,但可预防抗生素相关的菌群失调:一项针对健康志愿者的随机I期试验

Messaoudene, Meriem; Ferreira, Stéphanie; Saint-Lu, Nathalie; Ponce, Mayra; Truntzer, Caroline; Boidot, Romain; Le Bescop, Clément; Loppinet, Thomas; Corbel, Tanguy; Féger, Céline; Bertrand, Karine; Elkrief, Arielle; Isaksen, Morten; Vitry, Fabien; Sablier-Gallis, Frédérique; Andremont, Antoine; Bod, Lloyd; Ghiringhelli, François; de Gunzburg, Jean; Routy, Bertrand

Machine learning evaluation of immune infiltrate through digital tumour score allows prediction of survival outcome in a pooled analysis of three international stage III colon cancer cohorts

通过数字肿瘤评分对免疫浸润进行机器学习评估,可以预测三个国际 III 期结肠癌队列的汇总分析中的生存结果。

Lecuelle, Julie; Truntzer, Caroline; Basile, Debora; Laghi, Luigi; Greco, Luana; Ilie, Alis; Rageot, David; Emile, Jean-François; Bibeau, Fréderic; Taïeb, Julien; Derangere, Valentin; Lepage, Come; Ghiringhelli, François

Real-world prevalence, treatment and survival of "high risk" early breast cancer, with mandatory testing of gBRCA1/2 mutation according to the OlympiA trial inclusion criteria: Data from a population-based registry

基于人群登记研究的数据:真实世界中“高危”早期乳腺癌的患病率、治疗和生存情况,并根据 OlympiA 试验的纳入标准强制进行 gBRCA1/2 突变检测。

Ladoire, Sylvain; Mamguem Kamga, Ariane; Galland, Loick; Desmoulins, Isabelle; Mayeur, Didier; Kaderbhai, Courèche; Ilie, Silvia Mihaelia; Hennequin, Audrey; Jankowski, Clementine; Albuisson, Juliette; Nambot, Sophie; Coutant, Charles; Arnould, Laurent; Reda, Manon; Truntzer, Caroline; Dabakuyo, Sandrine

CD3-CD8 immune score associated with a clinical score stratifies PDAC prognosis regardless of adjuvant or neoadjuvant chemotherapy

CD3-CD8免疫评分与临床评分相结合,可对PDAC预后进行分层,而与辅助或新辅助化疗无关。

Schoumacher, Coralie; Derangère, Valentin; Gaudillière-Le Dain, Gwladys; Huppe, Titouan; Rageot, David; Ilie, Alis; Vienot, Angélique; Borg, Christophe; Monnien, Franck; Bibeau, Frederic; Truntzer, Caroline; Ghiringhelli, François

Effect of radiochemotherapy on peripheral immune response in glioblastoma.

放射化疗对胶质母细胞瘤外周免疫反应的影响

Hampe Léa, Daumoine Susy, Limagne Emeric, Roussot Nicolas, Borsotti François, Vincent Julie, Ilie Sylvia, Truntzer Caroline, Ghiringhelli François, Thibaudin Marion