日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Spatially Resolved, Multiregion Proteomics for Prediction of Immunotherapy Outcome in Deficient Mismatch Repair Metastatic Colorectal Cancer.

空间分辨多区域蛋白质组学预测错配修复缺陷型转移性结直肠癌的免疫治疗结果

Saberzadeh-Ardestani Bahar, Liu Zhenglong, Stein Mariam I, Sherman Will A, Trussoni Christy E, Abbott Charles W, Yan Dongyao, Smith Skyler, Shanmugam Kandavel, Graham Rondell P, Diallo Alos, Levy Joshua J, Ordog Tamas, Sinicrope Frank A

Targeting of a Bile Acid Receptor, Takeda G Protein Receptor 5 [TGR5], by a Novel First-in-Class Competitive Antagonist, SBI-364, Diminishes Hepatic and Renal Cystogenesis in Polycystic Liver and Kidney Disease

新型首创竞争性拮抗剂SBI-364靶向胆汁酸受体——武田G蛋白受体5 [TGR5],可减少多囊肝肾疾病中的肝肾囊肿形成。

Masyuk, Tetyana; Masyuk, Anatoliy; Trussoni, Christy; Lorenzo-Pisarello, Maria; Ardecky, Robert; Pinkerton, Anthony; Sergienko, Edward; Olson, Steven; Zou, Jiwen; Ganji, Santhi Reddy; Kramer, Bryan; Vuong, Krystine; Jankowski, She-Chia; Ma, Chen-Ting; Holleran, John; Pollari, Sirkku; Brown, Brock; Ramachandra, Raghuveer; Chung, Thomas; Turner, Carys; Morgenthaler, Olivia; Kawashima, Hanako; LaRusso, Nicholas

The Epigenetic Reader, Bromodomain Containing 2, Mediates Cholangiocyte Senescence via Interaction With ETS Proto-Oncogene 1

表观遗传读取器,含溴结构域 2,通过与 ETS 原癌基因 1 相互作用介导胆管细胞衰老

Jeong-Han Kang, Patrick L Splinter, Christy E Trussoni, Nicholas E Pirius, Gregory J Gores, Nicholas F LaRusso, Steven P O'Hara

Failure to repair endogenous DNA damage in β-cells causes adult-onset diabetes in mice

小鼠β细胞内源性DNA损伤修复失败会导致成年期糖尿病。

Yousefzadeh, Matthew J; Huerta Guevara, Ana P; Postmus, Andrea C; Flores, Rafael R; Sano, Tokio; Jurdzinski, Angelika; Angelini, Luise; McGowan, Sara J; O'Kelly, Ryan D; Wade, Erin A; Gonzalez-Espada, Lisa V; Henessy-Wack, Danielle; Howard, Shannon; Rozgaja, Tania A; Trussoni, Christy E; LaRusso, Nicholas F; Eggen, Bart J L; Jonker, Johan W; Robbins, Paul D; Niedernhofer, Laura J; Kruit, Janine K

Autophagy promotes hepatic cystogenesis in polycystic liver disease by depletion of cholangiocyte ciliogenic proteins

自噬通过消耗胆管细胞纤毛生成蛋白促进多囊肝病中的肝囊肿形成

Anatoliy I Masyuk, Tatyana V Masyuk, Christy E Trussoni, Nicholas E Pirius, Nicholas F LaRusso

Cellular senescence in the cholangiopathies: a driver of immunopathology and a novel therapeutic target

胆管疾病中的细胞衰老:免疫病理的驱动因素和新的治疗靶点

Trussoni, Christy E; O'Hara, Steven P; LaRusso, Nicholas F

An aged immune system drives senescence and ageing of solid organs

衰老的免疫系统导致实体器官的衰老和老化

Matthew J Yousefzadeh #, Rafael R Flores #, Yi Zhu, Zoe C Schmiechen, Robert W Brooks, Christy E Trussoni, Yuxiang Cui, Luise Angelini, Kyoo-A Lee, Sara J McGowan, Adam L Burrack, Dong Wang, Qing Dong, Aiping Lu, Tokio Sano, Ryan D O'Kelly, Collin A McGuckian, Jonathan I Kato, Michael P Bank, Erin A

Autophagy-mediated reduction of miR-345 contributes to hepatic cystogenesis in polycystic liver disease

自噬介导的 miR-345 减少促进多囊肝病中的肝囊肿形成

Masyuk, Tatyana; Masyuk, Anatoliy; Trussoni, Christy; Howard, Brynn; Ding, Jingyi; Huang, Bing; LaRusso, Nicholas

The Spectrum of Reactive Cholangiocytes in Primary Sclerosing Cholangitis

原发性硬化性胆管炎中反应性胆管细胞的谱系

Guicciardi, Maria Eugenia; Trussoni, Christy E; LaRusso, Nicholas F; Gores, Gregory J

Senescent cholangiocytes release extracellular vesicles that alter target cell phenotype via the epidermal growth factor receptor

衰老的胆管细胞释放细胞外囊泡,通过表皮生长因子受体改变靶细胞表型

Mohammed S Al Suraih, Christy E Trussoni, Patrick L Splinter, Nicholas F LaRusso, Steven P O'Hara