日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

ER remodelling is a feature of ageing and depends on ER-phagy

内质网重塑是衰老的一个特征,并且依赖于内质网自噬。

Donahue, Eric K F; Hepowit, Nathaniel L; Ruark, Elizabeth M; Mulligan, Alexandra G; Keuchel, Brennen; Urban, Nicholas D; Peng, Li; Stephens, Stedman; Johnson, Derek J; Wallace, Natalie S; Jackson, Lauren P; Ellisman, Mark H; Arrojo E Drigo, Rafael; Folkmann, Andrew W; Truttmann, Matthias C; MacGurn, Jason A; Burkewitz, Kristopher

HSP-1-specific nanobodies alter chaperone function in vitro and in vivo

HSP-1特异性纳米抗体在体外和体内均能改变分子伴侣的功能。

Urban, Nicholas D; Gharat, Kunal; Mattiola, Zachary J; Scheutzow, Ashley; Klaiss, Adam; Tabler, Sarah; Huffaker, Asa W; Grootveld, Monique; Skinner, Mary E; Zheng, Weiyang; O'Meara, Matthew J; Kirstein, Janine; Truttmann, Matthias C

Spatiotemporal brain dynamics in 8-to-9-year-old children: A comparative study between preterm and term schoolchildren

8至9岁儿童脑时空动力学:早产儿与足月儿的比较研究

Denervaud, Solange; Zanchi, Paola; Fischer Fumeaux, Céline J; Huguenin-Virchaux, Cléo; Besuchet, Laureline; Hagmann, Patric; Truttmann, Anita C; Schneider, Juliane

Increased FICD-mediated protein AMPylation triggers conserved endoplasmic reticulum stress signaling across species

FICD介导的蛋白质AMP化作用增强会触发跨物种保守的内质网应激信号通路。

Hernandez-Lima, Mirella A; Mariner, Blaise L; Giblin, William; McCormick, Mark A; Truttmann, Matthias C

Functionally diversified Caenorhabditis elegans BiP orthologs control body growth, reproduction, stress resistance, aging, and autophagy

功能多样化的秀丽隐杆线虫BiP同源基因控制着身体生长、繁殖、抗逆性、衰老和自噬。

Urban, Nicholas D; Lacy, Shannon M; Van Pelt, Kate M; Abdon, Benedict; Mattiola, Zachary; Klaiss, Adam; Tabler, Sarah; Donahue, Eric K F; Burkewitz, Kristopher; Truttmann, Matthias C

Modulation of C. elegans behavior, fitness, and lifespan by AWB/ASH-dependent death perception.

AWB/ASH依赖性死亡感知对秀丽隐杆线虫的行为、适应性和寿命的调节

Hernandez-Lima Mirella A, Seo Brian, Urban Nicholas D, Truttmann Matthias C

FICD (FIC Domain Protein Adenylyl Transferase) Deficiency Protects Mice From Hypertrophy-Induced Heart Failure and Promotes BiP (Binding Immunoglobulin Protein) -Mediated Activation of the Unfolded Protein Response and Endoplasmic Reticulum-Selective Autophagy in Cardiomyocytes.

FICD(FIC 结构域蛋白腺苷酰转移酶)缺乏可保护小鼠免受肥大引起的心力衰竭,并促进 BiP(结合免疫球蛋白蛋白)介导的未折叠蛋白反应和心肌细胞内质网选择性自噬的激活。

Lacy Shannon M, Taubitz Rebecca J, Urban Nicholas D, Turowski Samantha N, Primack Eric N, Smith Eric D, Helms Adam S, Michele Daniel E, Truttmann Matthias C

Exploring the Multifaceted Burdens and Experiences of Parents With a Child Diagnosed With Anorexia Nervosa: A Psychological Network Analysis

探索患有神经性厌食症儿童的父母所面临的多重负担和经历:一项心理网络分析

Zeiler, Michael; Philipp, Julia; Truttmann, Stefanie; Kopp, Konstantin; Schöfbeck, Gabriele; Mairhofer, Dunja; Imgart, Hartmut; Zanko, Annika; Auer-Welsbach, Ellen; Karwautz, Andreas; Wagner, Gudrun

Small-Molecule FICD Inhibitors Suppress Endogenous and Pathologic FICD-Mediated Protein AMPylation

小分子FICD抑制剂抑制内源性和病理性FICD介导的蛋白质AMP化。

Chatterjee, Bhaskar K; Alam, Maroof; Chakravorty, Arghya; Lacy, Shannon M; Giblin, William; Rech, Jason; Brooks, Charles L 3rd; Arvan, Peter; Truttmann, Matthias C

Loss of FIC-1-mediated AMPylation activates the UPRER and upregulates cytosolic HSP70 chaperones to suppress polyglutamine toxicity.

FIC-1 介导的 AMPylation 的丧失激活了 UPRER,并上调了胞质 HSP70 分子伴侣,从而抑制了多聚谷氨酰胺的毒性

Van Pelt Kate M, Truttmann Matthias C