日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

ER remodelling is a feature of ageing and depends on ER-phagy

内质网重塑是衰老的一个特征,并且依赖于内质网自噬。

Donahue, Eric K F; Hepowit, Nathaniel L; Ruark, Elizabeth M; Mulligan, Alexandra G; Keuchel, Brennen; Urban, Nicholas D; Peng, Li; Stephens, Stedman; Johnson, Derek J; Wallace, Natalie S; Jackson, Lauren P; Ellisman, Mark H; Arrojo E Drigo, Rafael; Folkmann, Andrew W; Truttmann, Matthias C; MacGurn, Jason A; Burkewitz, Kristopher

Increased FICD-mediated protein AMPylation triggers conserved endoplasmic reticulum stress signaling across species

FICD介导的蛋白质AMP化作用增强会触发跨物种保守的内质网应激信号通路。

Hernandez-Lima, Mirella A; Mariner, Blaise L; Giblin, William; McCormick, Mark A; Truttmann, Matthias C

Functionally diversified Caenorhabditis elegans BiP orthologs control body growth, reproduction, stress resistance, aging, and autophagy

功能多样化的秀丽隐杆线虫BiP同源基因控制着身体生长、繁殖、抗逆性、衰老和自噬。

Urban, Nicholas D; Lacy, Shannon M; Van Pelt, Kate M; Abdon, Benedict; Mattiola, Zachary; Klaiss, Adam; Tabler, Sarah; Donahue, Eric K F; Burkewitz, Kristopher; Truttmann, Matthias C

Modulation of C. elegans behavior, fitness, and lifespan by AWB/ASH-dependent death perception.

AWB/ASH依赖性死亡感知对秀丽隐杆线虫的行为、适应性和寿命的调节

Hernandez-Lima Mirella A, Seo Brian, Urban Nicholas D, Truttmann Matthias C

FICD (FIC Domain Protein Adenylyl Transferase) Deficiency Protects Mice From Hypertrophy-Induced Heart Failure and Promotes BiP (Binding Immunoglobulin Protein) -Mediated Activation of the Unfolded Protein Response and Endoplasmic Reticulum-Selective Autophagy in Cardiomyocytes.

FICD(FIC 结构域蛋白腺苷酰转移酶)缺乏可保护小鼠免受肥大引起的心力衰竭,并促进 BiP(结合免疫球蛋白蛋白)介导的未折叠蛋白反应和心肌细胞内质网选择性自噬的激活。

Lacy Shannon M, Taubitz Rebecca J, Urban Nicholas D, Turowski Samantha N, Primack Eric N, Smith Eric D, Helms Adam S, Michele Daniel E, Truttmann Matthias C

Loss of FIC-1-mediated AMPylation activates the UPRER and upregulates cytosolic HSP70 chaperones to suppress polyglutamine toxicity.

FIC-1 介导的 AMPylation 的丧失激活了 UPRER,并上调了胞质 HSP70 分子伴侣,从而抑制了多聚谷氨酰胺的毒性

Van Pelt Kate M, Truttmann Matthias C

GRAIL1 Stabilizes Misfolded Mutant p53 through a Ubiquitin Ligase-Independent, Chaperone Regulatory Function.

GRAIL1 通过不依赖于泛素连接酶的分子伴侣调节功能稳定错误折叠的突变型 p53

Ray Paramita, Jaiswal Sangeeta, Ferrer-Torres Daysha, Wang Zhuwen, Nancarrow Derek, Curtin Meghan, Martinho May San, Lacy Shannon M, Kasturirangan Srimathi, Thomas Dafydd, Spence Jason R, Truttmann Matthias C, Lagisetty Kiran H, Lawrence Theodore S, Wang Thomas D, Beer David G, Ray Dipankar

Editorial: A new chapter for Cell Stress and Chaperones

社论:细胞应激与分子伴侣研究的新篇章

Bourboulia, Dimitra; Blair, Laura J; Clark, Melody S; Edkins, Adrienne L; Hightower, Lawrence E; Mollapour, Mehdi; Prahlad, Veena; Repasky, Elizabeth A; Truebano, Manuela; Truman, Andrew W; Truttmann, Matthias C; van Oosten-Hawle, Patricija; Woodford, Mark R

A meta-analysis of RNA-Seq studies to identify novel genes that regulate aging

一项针对RNA-Seq研究的荟萃分析,旨在识别调控衰老的新基因

Bairakdar, Mohamad D; Tewari, Ambuj; Truttmann, Matthias C

Explaining inter-lab variance in C. elegans N2 lifespan: Making a case for standardized reporting to enhance reproducibility

解释秀丽隐杆线虫N2寿命的实验室间差异:论证标准化报告对于提高可重复性的必要性

Urban, Nicholas D; Cavataio, Joseph P; Berry, Yasmeen; Vang, Brandon; Maddali, Anirudh; Sukpraphrute, Richard J; Schnell, Santiago; Truttmann, Matthias C