日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Author Correction: Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents

作者更正：利用侵袭性真菌病原体的钙调磷酸酶-FK506-FKBP12晶体结构开发抗真菌药物

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-61584-6
Juvvadi, Praveen R; Fox, David 3rd; Bobay, Benjamin G; Hoy, Michael J; Gobeil, Sophie M C; Venters, Ronald A; Chang, Zanetta; Lin, Jackie J; Averette, Anna Floyd; Cole, D Christopher; Barrington, Blake C; Wheaton, Joshua D; Ciofani, Maria; Trzoss, Michael; Li, Xiaoming; Lee, Soo Chan; Chen, Ying-Lien; Mutz, Mitchell; Spicer, Leonard D; Schumacher, Maria A; Heitman, Joseph; Steinbach, William J
微生物学
发表日期：2025
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Author Correction: JT002, a small molecule inhibitor of the NLRP3 inflammasome for the treatment of autoinflammatory disorders

作者更正：JT002 是一种用于治疗自身炎症性疾病的 NLRP3 炎症小体小分子抑制剂。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-023-47251-0
Ambrus-Aikelin, Geza; Takeda, Katsuyuki; Joetham, Anthony; Lazic, Milos; Povero, Davide; Santini, Angelina M; Pranadinata, Rama; Johnson, Casey D; McGeough, Matthew D; Beasley, Federico C; Stansfield, Ryan; McBride, Christopher; Trzoss, Lynnie; Hoffman, Hal M; Feldstein, Ariel E; Stafford, Jeffrey A; Veal, James M; Bain, Gretchen; Gelfand, Erwin W
LRP3
NLRP3
炎性小体
炎性小体
免疫/内分泌
炎症
炎症/感染
发表日期：2023
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JT002, a small molecule inhibitor of the NLRP3 inflammasome for the treatment of autoinflammatory disorders

JT002，一种 NLRP3 炎症小体的小分子抑制剂，用于治疗自身炎症性疾病

期刊:Scientific Reports
影响因子:3.8
doi:10.1038/s41598-023-39805-z
Geza Ambrus-Aikelin, Katsuyuki Takeda, Anthony Joetham, Milos Lazic, Davide Povero, Angelina M Santini, Rama Pranadinata, Casey D Johnson, Matthew D McGeough, Federico C Beasley, Ryan Stansfield, Christopher McBride, Lynnie Trzoss, Hal M Hoffman, Ariel E Feldstein, Jeffrey A Stafford, James M Veal, 
信号转导
炎性小体
发表日期：2023
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Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents

利用侵袭性真菌病原体的钙调神经磷酸酶-FK506-FKBP12 晶体结构开发抗真菌剂

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-019-12199-1
Praveen R Juvvadi, David Fox 3rd, Benjamin G Bobay, Michael J Hoy, Sophie M C Gobeil, Ronald A Venters, Zanetta Chang, Jackie J Lin, Anna Floyd Averette, D Christopher Cole, Blake C Barrington, Joshua D Wheaton, Maria Ciofani, Michael Trzoss, Xiaoming Li, Soo Chan Lee, Ying-Lien Chen, Mitchell Mutz,
神经
发表日期：2019
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APX001 and Other Gwt1 Inhibitor Prodrugs Are Effective in Experimental Coccidioides immitis Pneumonia

APX001 和其他 Gwt1 抑制剂前药对实验性粗球孢子菌肺炎有效

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.01715-18
Viriyakosol, Suganya; Kapoor, Mili; Okamoto, Sharon; Covel, Jonathan; Soltow, Quinlyn A; Trzoss, Michael; Shaw, Karen Joy; Fierer, Joshua
肺炎
发表日期：2019
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Advance of Seriniquinone Analogues as Melanoma Agents

丝氨酸醌类似物作为黑色素瘤治疗药物的进展

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.8b00391
Hammons, Justin C; Trzoss, Lynnie; Jimenez, Paula C; Hirata, Amanda S; Costa-Lotufo, Leticia V; La Clair, James J; Fenical, William
黑色素瘤
发表日期：2019
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Synthesis of analogs of the Gwt1 inhibitor manogepix (APX001A) and in vitro evaluation against Cryptococcus spp

合成Gwt1抑制剂manogepix（APX001A）类似物并进行体外抗隐球菌属活性评价

期刊:Bioorganic & Medicinal Chemistry Letters
影响因子:2.2
doi:10.1016/j.bmcl.2019.126713
Trzoss, Michael; Covel, Jonathan A; Kapoor, Mili; Moloney, Molly K; Soltow, Quinlyn A; Webb, Peter J; Shaw, Karen Joy
发表日期：2019
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Integration of Genomic Data with NMR Analysis Enables Assignment of the Full Stereostructure of Neaumycin B, a Potent Inhibitor of Glioblastoma from a Marine-Derived Micromonospora

基因组数据与 NMR 分析的整合可以确定新霉素 B 的完整立体结构，新霉素 B 是一种来自海洋微单孢菌的胶质母细胞瘤强效抑制剂

期刊:Journal of the American Chemical Society
影响因子:14.4
doi:10.1021/jacs.8b04848
Min Cheol Kim, Henrique Machado, Kyoung Hwa Jang, Lynnie Trzoss, Paul R Jensen, William Fenical
微生物学
细胞生物学
肿瘤
胶质瘤
其它细胞
发表日期：2018
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A commensal strain of Staphylococcus epidermidis protects against skin neoplasia

表皮葡萄球菌的一种共生菌株可预防皮肤肿瘤。

期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.aao4502
Nakatsuji, Teruaki; Chen, Tiffany H; Butcher, Anna M; Trzoss, Lynnie L; Nam, Sang-Jip; Shirakawa, Karina T; Zhou, Wei; Oh, Julia; Otto, Michael; Fenical, William; Gallo, Richard L
微生物学
肿瘤
肿瘤免疫
发表日期：2018
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In Vitro and In Vivo Evaluation of APX001A/APX001 and Other Gwt1 Inhibitors against Cryptococcus

体外和体内评价 APX001A/APX001 和其他 Gwt1 抑制剂对隐球菌的活性

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.00523-18
Shaw, Karen Joy; Schell, Wiley A; Covel, Jonathan; Duboc, Gisele; Giamberardino, C; Kapoor, Mili; Moloney, Molly; Soltow, Quinlyn A; Tenor, Jennifer L; Toffaletti, Dena L; Trzoss, Michael; Webb, Peter; Perfect, John R
发表日期：2018
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