Tsai Hui-Hsin相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

First-in-Human Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Ascending Oral Doses of BIIB091, an Oral BTK Inhibitor, in Healthy Adult Participants

在健康成年受试者中首次进行口服 BTK 抑制剂 BIIB091 单次和多次递增口服剂量的人体安全性、耐受性、药代动力学和药效学研究

期刊:Drug Design Development and Therapy

影响因子:5.1

doi:10.2147/DDDT.S571780

Tsai, Hui-Hsin; Gu, Yi; Riester, Katherine; Chu, Sherman S; Bame, Eris; Arefayene, Million; Kam, Jeanelle L Y L; Coppell, Alexander; Hanna, Jerome; Hopkins, Brian T; Scaramozza, Matthew

发表日期：2026

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Serum metabolomic-lipidomic signatures track long-term neurological performance in multiple sclerosis

血清代谢组学-脂质组学特征可追踪多发性硬化症患者的长期神经功能表现

doi:10.1186/s44477-025-00008-7

Noroozi, Rose; Tsai, Hui-Hsin; Yu, Ketian; Samuel, Karunakar; Trinh, Kien; Tsai, Ellen A; Briggs, Farren B S; Bhargava, Pavan; Fitzgerald, Kathryn C

多发性硬化症

发表日期：2026

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Scaling up spatial transcriptomics for large-sized tissues: uncovering cellular-level tissue architecture beyond conventional platforms with iSCALE

利用 iSCALE 将空间转录组学扩展到大尺寸组织：揭示超越传统平台的细胞级组织结构

期刊:Nature Methods

影响因子:32.1

doi:10.1038/s41592-025-02770-8

Schroeder, Amelia; Loth, Melanie L; Luo, Chunyu; Yao, Sicong; Yan, Hanying; Zhang, Daiwei; Piya, Sarbottam; Plowey, Edward; Hu, Wenxing; Clemenceau, Jean R; Jang, Inyeop; Kim, Minji; Barnfather, Isabel; Chan, Su Jing; Reynolds, Taylor L; Carlile, Thomas; Cullen, Patrick; Sung, Ji-Youn; Tsai, Hui-Hsin; Park, Jeong Hwan; Hwang, Tae Hyun; Zhang, Baohong; Li, Mingyao

细胞生物学

发表日期：2025

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Metabolic and lipid alterations in multiple sclerosis linked to disease severity

多发性硬化症的代谢和脂质改变与疾病严重程度相关

期刊:Multiple Sclerosis Journal

doi:10.1177/13524585251325468

Noroozi, Rezvan; Tsai, Hui-Hsin; Yu, Ketian; Bronson, Paola; Samuel, Karunakar; Trinh, Kien; Wei, Ru; Tsai, Ellen; Briggs, Farren Bs; Bhargava, Pavan; Fitzgerald, Kathryn C

多发性硬化症

发表日期：2025

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Scaling up spatial transcriptomics for large-sized tissues: uncovering cellular-level tissue architecture beyond conventional platforms with iSCALE.

利用 iSCALE 将空间转录组学扩展到大组织：揭示超越传统平台的细胞级组织结构

doi:10.1101/2025.02.25.640190

Schroeder Amelia, Loth Melanie, Luo Chunyu, Yao Sicong, Yan Hanying, Zhang Daiwei, Piya Sarbottam, Plowey Edward, Hu Wenxing, Clemenceau Jean R, Jang Inyeop, Kim Minji, Barnfather Isabel, Chan Su Jing, Reynolds Taylor L, Carlile Thomas, Cullen Patrick, Sung Ji-Youn, Tsai Hui-Hsin, Park Jeong Hwan, Hwang Tae Hyun, Zhang Baohong, Li Mingyao

细胞生物学

发表日期：2025

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Dysregulation of locus coeruleus development in congenital central hypoventilation syndrome

先天性中枢性低通气综合征中蓝斑发育失调

期刊:Acta Neuropathologica

影响因子:9.3

doi:10.1007/s00401-015-1441-0

Nobuta, Hiroko; Cilio, Maria Roberta; Danhaive, Olivier; Tsai, Hui-Hsin; Tupal, Srinivasan; Chang, Sandra M; Murnen, Alice; Kreitzer, Faith; Bravo, Verenice; Czeisler, Catherine; Gokozan, Hamza Numan; Gygli, Patrick; Bush, Sean; Weese-Mayer, Debra E; Conklin, Bruce; Yee, Siu-Pok; Huang, Eric J; Gray, Paul A; Rowitch, David; Otero, José Javier

发育与干细胞

发表日期：2015

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Olig1 function is required to repress dlx1/2 and interneuron production in Mammalian brain

Olig1的功能对于抑制哺乳动物大脑中的dlx1/2和中间神经元的产生是必需的。

影响因子:15

doi:10.1016/j.neuron.2013.11.024

Silbereis, John C; Nobuta, Hiroko; Tsai, Hui-Hsin; Heine, Vivi M; McKinsey, Gabriel L; Meijer, Dimphna H; Howard, Mackenzie A; Petryniak, Magda A; Potter, Gregory B; Alberta, John A; Baraban, Scott C; Stiles, Charles D; Rubenstein, John L R; Rowitch, David H

发表日期：2014

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Astrocytes and disease: a neurodevelopmental perspective

星形胶质细胞与疾病：神经发育视角

期刊:Genes & Development

影响因子:7.7

doi:10.1101/gad.188326.112

Molofsky, Anna V; Krencik, Robert; Ullian, Erik M; Tsai, Hui-hsin; Deneen, Benjamin; Richardson, William D; Barres, Ben A; Rowitch, David H

细胞生物学

发育与干细胞

发表日期：2012

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Regulated temporal-spatial astrocyte precursor cell proliferation involves BRAF signalling in mammalian spinal cord

哺乳动物脊髓中星形胶质细胞前体细胞增殖的时空调控涉及BRAF信号通路

期刊:Development

影响因子:3.6

doi:10.1242/dev.077214

Tien, An-Chi; Tsai, Hui-Hsin; Molofsky, Anna V; McMahon, Martin; Foo, Lynette C; Kaul, Aparna; Dougherty, Joseph D; Heintz, Nathaniel; Gutmann, David H; Barres, Ben A; Rowitch, David H

细胞生物学

发表日期：2012

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Distinct modes of migration position oligodendrocyte precursors for localized cell division in the developing spinal cord

不同的迁移模式将少突胶质细胞前体定位到发育中的脊髓中进行局部细胞分裂。

期刊:Journal of Neuroscience Research

影响因子:3.4

doi:10.1002/jnr.22058

Tsai, Hui-Hsin; Macklin, Wendy B; Miller, Robert H

细胞生物学

发育与干细胞

发表日期：2009

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