日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Combinatorial immunotherapy drives exhaustion in tumor antigen-specific CD8+ T cells within the mouse renal tumor microenvironment.

联合免疫疗法导致小鼠肾肿瘤微环境中肿瘤抗原特异性 CD8+ T 细胞耗竭。

Stephens Holly R, Elkins Elizabeth, Li Jing, Swalley Zoey N, Ogbonna Henry Nnaemeka, Muri Pia, Roberts Zachary, Dempsey Francesca R, Ali Md Akkas, Siam Md Hasanul Banna, Kirkman Richard, Zhang Jianqing, Sudarshan Sunil, Tyrrell Daniel J, Tse Hubert M, Smith Daniel L Jr, Norian Lyse A

Islet-intrinsic sex differences in inflammatory signaling contribute to autoimmune diabetes susceptibility

胰岛自身炎症信号传导的性别差异导致自身免疫性糖尿病易感性

Webster, Kierstin L; Puente, Armando A; Enriquez, Jacob R; Sarkar, Soumyadeep; Nakayasu, Ernesto S; Webb-Robertson, Bobbie-Jo M; Bramer, Lisa M; Figatner, Kayla; Pratuangtham, Sarida; Wu, Wenting; Evans-Molina, Carmella; Tse, Hubert M; Roy, Saptarshi; Piganelli, Jon D; Hammes, Stephen R; Tersey, Sarah A; Mirmira, Raghavendra G

Protective IFIH1 variant reduces immune-mediated islet stress and dysfunction in a type 1 diabetes genetic background.

保护性 IFIH1 变体可降低 1 型糖尿病遗传背景下的免疫介导的胰岛应激和功能障碍。

Veronese-Paniagua Daniel A, Banks Cameron, Bradley Kameron, Mukherjee Noyonika, Gale Sarah E, Hinshaw Kate E, Meacham Amy M, Iwaloye Opeoluwa F, Tse Hubert M, Mathews Clayton E, Millman Jeffrey R

A static glucose-stimulated insulin secretion (sGSIS) assay that is significantly predictive of time to diabetes reversal in the human islet bioassay

一种静态葡萄糖刺激胰岛素分泌 (sGSIS) 检测方法,可显著预测人胰岛生物测定中糖尿病逆转所需的时间。

Molano, Ruth Damaris; Pileggi, Antonello; Tse, Hubert M; Stabler, Cherie L; Fraker, Christopher A

The Type 1 Diabetes-Associated Single Nucleotide Polymorphism rs1990760 in IFIH1 Is Associated with Increased Basal Type I IFNs and IFN-stimulated Gene Expression

1 型糖尿病相关单核苷酸多态性 rs1990760(位于 IFIH1 基因)与基础 I 型干扰素水平升高和干扰素刺激基因表达增强相关。

Taylor, Jared P; Blum, Samuel I; Graffeo, Hollis C; Shang, Qiao; Qiu, Shihong; Green, Todd J; Botta, Davide; Lund, Frances E; Tse, Hubert M

Electrospun Fiber Surface Roughness Modulates Human Monocyte-Derived Macrophage Phenotype

静电纺丝纤维表面粗糙度调节人单核细胞来源的巨噬细胞表型

Alemifar, Aidan; Burnette, KaLia; Jandres, Bryan; Hurt, Samuel; Tse, Hubert M; Robinson, Jennifer L

Localized cytotoxic T cell-associated antigen 4 and antioxidant islet encapsulation alters macrophage signaling and induces regulatory and anergic T cells to enhance allograft survival.

局部细胞毒性 T 细胞相关抗原 4 和抗氧化剂胰岛封装可改变巨噬细胞信号传导,并诱导调节性 T 细胞和无反应性 T 细胞,从而增强同种异体移植存活率

Barra Jessie M, Kozlovskaya Veronika, Burnette KaLia S, Banerjee Ronadip R, Fraker Christopher A, Kharlampieva Eugenia, Tse Hubert M

Nanothin Conformal Coating with Poly(N-vinylpyrrolidone) and Tannic Acid (PVPON/TA) Preserves Murine and Human Pancreatic Islets Function

采用聚乙烯吡咯烷酮和单宁酸(PVPON/TA)的纳米级保形涂层可保护小鼠和人胰岛的功能。

Polishevska, Kateryna; Kelly, Sandra; Kuppan, Purushothaman; Seeberger, Karen L; Aggarwal, Saloni; Paramor, Joy; Unsworth, Larry D; Tse, Hubert M; Korbutt, Gregory S; Pepper, Andrew R

Exploratory study reveals far reaching systemic and cellular effects of verapamil treatment in subjects with type 1 diabetes

探索性研究揭示了维拉帕米治疗对1型糖尿病患者的深远全身性和细胞性影响

Xu, Guanlan; Grimes, Tiffany D; Grayson, Truman B; Chen, Junqin; Thielen, Lance A; Tse, Hubert M; Li, Peng; Kanke, Matt; Lin, Tai-Tu; Schepmoes, Athena A; Swensen, Adam C; Petyuk, Vladislav A; Ovalle, Fernando; Sethupathy, Praveen; Qian, Wei-Jun; Shalev, Anath

A randomized trial of oral gamma aminobutyric acid (GABA) or the combination of GABA with glutamic acid decarboxylase (GAD) on pancreatic islet endocrine function in children with newly diagnosed type 1 diabetes

一项随机试验,旨在研究口服γ-氨基丁酸(GABA)或GABA联合谷氨酸脱羧酶(GAD)对新诊断为1型糖尿病儿童胰岛内分泌功能的影响。

Martin, Alexandra; Mick, Gail J; Choat, Heather M; Lunsford, Alison A; Tse, Hubert M; McGwin, Gerald G Jr; McCormick, Kenneth L