Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING
BRCA1缺陷型卵巢癌的细胞自主性炎症通过STING驱动肿瘤固有的免疫反应性和免疫抵抗。
期刊:Cell Reports
影响因子:7.5
doi:10.1016/j.celrep.2021.109412
Marine Bruand,David Barras,Marco Mina,Eleonora Ghisoni,Matteo Morotti,Evripidis Lanitis,Noémie Fahr,Mathieu Desbuisson,Alizée Grimm,Hualing Zhang,Chloe Chong,Julien Dagher,Sora Chee,Theodora Tsianou,Julien Dorier,Brian J Stevenson,Christian Iseli,Catherine Ronet,Sara Bobisse,Raphael Genolet,Josephine Walton,Michal Bassani-Sternberg,Lana E Kandalaft,Bing Ren,Iain McNeish,Elizabeth Swisher,Alexandre Harari,Mauro Delorenzi,Giovanni Ciriello,Melita Irving,Sylvie Rusakiewicz,Periklis G Foukas,Fabio Martinon,Denarda Dangaj Laniti,George Coukos
卵巢癌
细胞生物学
肿瘤
炎症/感染
肿瘤
免疫/内分泌
BRCA1
STING
Immunology/Inflammation
炎症
