日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Dual role of Tropomyosin-R160 in thin filament regulation: Insights into phosphorylation-dependent cardiac relaxation and cardiomyopathy mechanisms

原肌球蛋白R160在细肌丝调节中的双重作用:对磷酸化依赖性心脏舒张和心肌病机制的深入理解

Barry, Meaghan E; Rynkiewicz, Michael J; Wen, Jian; Tu, An-Yue; Regnier, Michael; Lehman, William; Moore, Jeffrey R

Calcium has a direct effect on thick filament activation in porcine myocardium

钙对猪心肌粗丝活化有直接作用

Mohran, Saffie; McMillen, Timothy S; Mandrycky, Christian; Tu, An-Yue; Kooiker, Kristina B; Qian, Wenjing; Neys, Stephanie; Osegueda, Brayan; Moussavi-Harami, Farid; Irving, Thomas C; Regnier, Michael; Ma, Weikang

Effects of Cardiac Troponin I Mutation P83S on Contractile Properties and the Modulation by PKA-Mediated Phosphorylation.

心肌肌钙蛋白 I 突变 P83S 对收缩特性的影响及 PKA 介导的磷酸化调节

Cheng Yuanhua, Lindert Steffen, Oxenford Lucas, Tu An-Yue, McCulloch Andrew D, Regnier Michael

Troponin I Mutations R146G and R21C Alter Cardiac Troponin Function, Contractile Properties, and Modulation by Protein Kinase A (PKA)-mediated Phosphorylation.

肌钙蛋白 I 突变 R146G 和 R21C 改变心脏肌钙蛋白功能、收缩特性以及蛋白激酶 A (PKA) 介导的磷酸化调节

Cheng Yuanhua, Rao Vijay, Tu An-Yue, Lindert Steffen, Wang Dan, Oxenford Lucas, McCulloch Andrew D, McCammon J Andrew, Regnier Michael

Thin filament incorporation of an engineered cardiac troponin C variant (L48Q) enhances contractility in intact cardiomyocytes from healthy and infarcted hearts

将一种工程化的心肌肌钙蛋白C变体(L48Q)整合到细丝中,可增强健康和梗死心脏的完整心肌细胞的收缩力。

Feest, Erik R; Steven Korte, F; Tu, An-Yue; Dai, Jin; Razumova, Maria V; Murry, Charles E; Regnier, Michael

Structural and functional consequences of cardiac troponin C L57Q and I61Q Ca(2+)-desensitizing variants

心肌肌钙蛋白C L57Q和I61Q Ca(2+)脱敏变异体的结构和功能后果

Wang, Dan; McCully, Michelle E; Luo, Zhaoxiong; McMichael, Jonathan; Tu, An-Yue; Daggett, Valerie; Regnier, Michael

Enhanced Ca2+ binding of cardiac troponin reduces sarcomere length dependence of contractile activation independently of strong crossbridges.

心肌肌钙蛋白的 Ca2+ 结合增强,降低了收缩激活对肌节长度的依赖性,而与强横桥无关

Korte F Steven, Feest Erik R, Razumova Maria V, Tu An-Yue, Regnier Michael

Structural and functional consequences of the cardiac troponin C L48Q Ca(2+)-sensitizing mutation

心肌肌钙蛋白C L48Q Ca(2+) 敏感突变的结构和功能后果

Wang, Dan; Robertson, Ian M; Li, Monica X; McCully, Michelle E; Crane, Melissa L; Luo, Zhaoxiong; Tu, An-Yue; Daggett, Valerie; Sykes, Brian D; Regnier, Michael

Contribution of the myosin binding protein C motif to functional effects in permeabilized rat trabeculae.

肌球蛋白结合蛋白 C 基序对透化大鼠小梁功能效应的贡献

Razumova Maria V, Bezold Kristina L, Tu An-Yue, Regnier Michael, Harris Samantha P