日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Microwave-Assisted Synthesis of Imidazole-Based Chalcones: Modulating Antimicrobial Activity Through Alkoxy Substitutions

微波辅助合成咪唑基查尔酮：通过烷氧基取代调节抗菌活性

期刊:Antibiotics-Basel
影响因子:4.6
doi:10.3390/antibiotics15030310
Mammadov, Elnar; Bayrak, Nilüfer; Beyazit, Neslihan; Mataraci-Kara, Emel; TuYuN, Amaç Fatih
发表日期：2026
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Structure and Dynamics of the ABL1 Tyrosine Kinase and Its Important Role in Chronic Myeloid Leukemia

ABL1酪氨酸激酶的结构和动力学及其在慢性粒细胞白血病中的重要作用

期刊:Archiv der Pharmazie
影响因子:3.6
doi:10.1002/ardp.70005
Irgit, Ayca; Kamıs, Reyhan; Sever, Belgin; Tuyun, Amaç Fatih; Otsuka, Masami; Fujita, Mikako; Demirci, Hasan; Ciftci, Halilibrahim
信号转导
ABL1
粒细胞
白血病
细胞生物学
发表日期：2025
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Targeting Cancer Cell Proliferation Using Piperazine-Linked Quinolinequinones: Mechanism and Metabolic Profile.

利用哌嗪连接的喹啉醌类化合物靶向抑制癌细胞增殖：机制和代谢特征

期刊:Chemical Biology & Drug Design
影响因子:3.3
doi:10.1111/cbdd.70139
Yilmaz Ayse Mine, Jannuzzi Ayse Tarbin, Biswas Abanish, Mondal Subodh, Basavanakatti Vinay N, Yıldırım Hatice, Yıldız Mahmut, Bayrak Nilüfer, Jayaprakash Venkatesan, TuYuN Amaç Fatih
代谢
发表日期：2025
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Design, Synthesis, and Mechanistic Anticancer Evaluation of New Pyrimidine-Tethered Compounds

新型嘧啶束缚化合物的设计、合成及抗癌机理评估

期刊:Pharmaceuticals
影响因子:
doi:10.3390/ph18020270
Farida Reymova, Belgin Sever, Edanur Topalan, Canan Sevimli-Gur, Mustafa Can, Amaç Fatih Tuyun, Faika Başoğlu, Abdulilah Ece, Masami Otsuka, Mikako Fujita, Hasan Demirci, Halilibrahim Ciftci0
肿瘤
EGFR
发表日期：2025
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Scaffold Hopping and Structural Modification of NSC 663284: Discovery of Potent (Non)Halogenated Aminobenzoquinones

NSC 663284 的骨架跳跃和结构修饰：发现有效的（非）卤代氨基苯醌

期刊:Biomedicines
影响因子:3.9
doi:10.3390/biomedicines12010050
Nilüfer Bayrak, Belgin Sever, Halilibrahim Ciftci, Masami Otsuka, Mikako Fujita, Amaç Fatih TuYuN
信号转导
发表日期：2023
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Exploring the Anticancer Effects of Brominated Plastoquinone Analogs with Promising Cytotoxic Activity in MCF-7 Breast Cancer Cells via Cell Cycle Arrest and Oxidative Stress Induction

探索溴化质体醌类似物通过诱导细胞周期阻滞和氧化应激发挥抗癌作用，该类似物在MCF-7乳腺癌细胞中具有良好的细胞毒活性。

期刊:Pharmaceuticals
影响因子:4.8
doi:10.3390/ph15070777
Jannuzzi, Ayse Tarbin; Yilmaz Goler, Ayse Mine; Bayrak, Nilüfer; Yıldız, Mahmut; Yıldırım, Hatice; Karademir Yilmaz, Betul; Shilkar, Deepak; Venkatesan, Raghusrinivasan Jayaprakash; Jayaprakash, Venkatesan; TuYuN, Amaç Fatih
肿瘤
肿瘤免疫
氧化应激
乳腺癌
细胞生物学
毒理研究
发表日期：2022
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Promising Antibacterial and Antifungal Agents Based on Thiolated Vitamin K3 Analogs: Synthesis, Bioevaluation, Molecular Docking

基于硫醇化维生素K3类似物的潜在抗菌和抗真菌剂：合成、生物活性评价、分子对接

期刊:Pharmaceuticals
影响因子:4.8
doi:10.3390/ph15050586
Yıldırım, Hatice; Yıldız, Mahmut; Bayrak, Nilüfer; Mataracı-Kara, Emel; Radwan, Mohamed Osman; Jannuzzi, Ayse Tarbin; Otsuka, Masami; Fujita, Mikako; TuYuN, Amaç Fatih
微生物学
发表日期：2022
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In Vitro Cytotoxicity Evaluation of Plastoquinone Analogues against Colorectal and Breast Cancers along with In Silico Insights.

体外细胞毒性评价Plastoquinone类似物对结直肠癌和乳腺癌的毒性及计算机模拟结果

期刊:Pharmaceuticals
影响因子:4.8
doi:10.3390/ph15101266
Ciftci Halilibrahim, Sever Belgin, Bayrak Nilüfer, Yıldız Mahmut, Yıldırım Hatice, Tateishi Hiroshi, Otsuka Masami, Fujita Mikako, TuYuN Amaç Fatih
细胞生物学
乳腺癌
肠癌
发表日期：2022
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Natural-product-inspired design and synthesis of thiolated coenzyme Q analogs as promising agents against Gram-positive bacterial strains: insights into structure-activity relationship, activity profile, mode of action, and molecular docking

受天然产物启发，设计并合成硫醇化辅酶Q类似物作为抗革兰氏阳性菌的潜在药物：结构-活性关系、活性谱、作用机制和分子对接研究

期刊:RSC Advances
影响因子:4.6
doi:10.1039/d2ra02136f
Yıldırım, Hatice; Yıldız, Mahmut; Bayrak, Nilüfer; Mataracı-Kara, Emel; Özbek-Çelik, Berna; Otsuka, Masami; Fujita, Mikako; Radwan, Mohamed O; TuYuN, Amaç Fatih
发表日期：2022
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Highly Active Small Aminated Quinolinequinones against Drug-Resistant Staphylococcus aureus and Candida albicans

高效活性小分子氨基喹啉醌类化合物对抗耐药金黄色葡萄球菌和白色念珠菌

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules27092923
Yıldırım, Hatice; Bayrak, Nilüfer; Yıldız, Mahmut; Yılmaz, Fatıma Nur; Mataracı-Kara, Emel; Shilkar, Deepak; Jayaprakash, Venkatesan; TuYuN, Amaç Fatih
发表日期：2022
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