日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Light-induced analgesia provides a drug-free optical method for pain relief via activation of TRAAK k(+) channels

光诱导镇痛提供了一种无需药物的光学镇痛方法，其原理是通过激活TRAAK k(+)通道。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-67819-w
Bied, Marion; Landra-Willm, Arnaud; Chassot, Anne Amandine; Mendez-Otalvaro, Edward Francisco; Sueur, Benjamin; Roßmann, Kilian; de la Peña, Elvira; Fossat, Pascal; Tucker, Stephen J; Noël, Jacques; Kopec, Wojciech; Viana, Felix; Broichhagen, Johannes; Boué-Grabot, Eric; Sandoz, Guillaume
发表日期：2026
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Structural determinants for GPCR-mediated inhibition of TASK K2P channels by diacylglycerol and its dysfunction in disease

二酰甘油通过GPCR介导抑制TASK K2P通道的结构决定因素及其在疾病中的功能障碍

期刊:EMBO Journal
影响因子:8.3
doi:10.1038/s44318-026-00710-6
Jouen-Tachoire, Thibault R H; Proks, Peter; Seiferth, David; Crowther, Kate; Biggin, Philip C; Baukrowitz, Thomas; Schewe, Marcus; Tucker, Stephen J
GPCR/Calcium/cAMP
发表日期：2026
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Cryo-EM structure of the human THIK-1 K2P K(+) channel reveals a lower Y gate regulated by lipids and anesthetics

人THIK-1 K2P K(+)通道的冷冻电镜结构揭示了一个受脂质和麻醉剂调控的较低Y门控

期刊:Nature Structural & Molecular Biology
影响因子:10.1
doi:10.1038/s41594-025-01497-6
Rödström, Karin E J; Eymsh, Bisher; Proks, Peter; Hayre, Mehtab S; Cordeiro, Sönke; Mendez-Otalvaro, Edward; Madry, Christian; Rowland, Anna; Kopec, Wojciech; Newstead, Simon; Baukrowitz, Thomas; Schewe, Marcus; Tucker, Stephen J
信号转导
发表日期：2025
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Electronic Polarizability Tunes the Function of the Human Bestrophin 1 Cl(-) Channel

电子极化率调节人Bestrophin 1 Cl(-)通道的功能

期刊:Journal of Chemical Theory and Computation
影响因子:5.5
doi:10.1021/acs.jctc.4c01039
Phan, Linda X; Owji, Aaron P; Yang, Tingting; Crain, Jason; Sansom, Mark S P; Tucker, Stephen J
Human
发表日期：2025
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Structures of TASK-1 and TASK-3 K2P channels provide insight into their gating and dysfunction in disease.

TASK-1 和 TASK-3 K2P 通道的结构揭示了它们在疾病中的门控和功能障碍

期刊:Structure
影响因子:4.3
doi:10.1016/j.str.2024.11.005
Hall Peter Rory, Jouen-Tachoire Thibault, Schewe Marcus, Proks Peter, Baukrowitz Thomas, Carpenter Elisabeth P, Newstead Simon, Rödström Karin E J, Tucker Stephen J
发表日期：2025
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Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation

利用纳米抗体对TREK-2活性进行细胞外调控，有助于深入了解K2P通道调控机制。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-024-48536-2
Rödström, Karin E J; Cloake, Alexander; Sörmann, Janina; Baronina, Agnese; Smith, Kathryn H M; Pike, Ashley C W; Ang, Jackie; Proks, Peter; Schewe, Marcus; Holland-Kaye, Ingelise; Bushell, Simon R; Elliott, Jenna; Pardon, Els; Baukrowitz, Thomas; Owens, Raymond J; Newstead, Simon; Steyaert, Jan; Carpenter, Elisabeth P; Tucker, Stephen J
信号转导
细胞生物学
发表日期：2024
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Influence of electronic polarization on the binding of anions to a chloride-pumping rhodopsin

电子极化对阴离子与氯离子泵视紫红质结合的影响

期刊:Biophysical Journal
影响因子:3.1
doi:10.1016/j.bpj.2023.03.026
Phan, Linda X; Chamorro, Victor Cruces; Martinez-Seara, Hector; Crain, Jason; Sansom, Mark S P; Tucker, Stephen J
发表日期：2023
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Limitations of non-polarizable force fields in describing anion binding poses in non-polar synthetic hosts

非极化力场在描述非极性合成主体中阴离子结合姿态方面的局限性

期刊:Physical Chemistry Chemical Physics
影响因子:2.9
doi:10.1039/d3cp00479a
Seiferth, David; Tucker, Stephen J; Biggin, Philip C
发表日期：2023
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Transcending Markov: non-Markovian rate processes of thermosensitive TRP ion channels

超越马尔可夫：热敏TRP离子通道的非马尔可夫速率过程

期刊:Royal Society Open Science
影响因子:2.9
doi:10.1098/rsos.230984
Ben-Abu, Yuval; Tucker, Stephen J; Contera, Sonia
发表日期：2023
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Correction: Limitations of non-polarizable force fields in describing anion binding poses in non-polar synthetic hosts

更正：非极化力场在描述非极性合成主体中阴离子结合姿势方面的局限性

期刊:Physical Chemistry Chemical Physics
影响因子:2.9
doi:10.1039/d3cp90150e
Seiferth, David; Tucker, Stephen J; Biggin, Philip C
发表日期：2023
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