日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Prolonging lung cancer response to EGFR inhibition by targeting the selective advantage of resistant cells

通过靶向耐药细胞的选择性优势来延长肺癌对 EGFR 抑制剂的反应时间

Brunet, Lisa; Alexandre, David; Lee, Jiyoung; Blanquer-Rosselló, Maria Del Mar; Bracquemond, David; Guernet, Alexis; Chhouri, Houssein; Goupil, Mathilde; Kherrouche, Zoulika; Arabo, Arnaud; Mancini, Maicol; Cartier, Dorthe; Yao, Shen; Godefroy, David; Dehedin, Julie; Li, Jian-Rong; Duparc, Céline; Jamme, Philippe; Vinchent, Audrey; Bérard, Caroline; Tulasne, David; Arena, Sabrina; Bardelli, Alberto; Cheng, Chao; Cho, Byoung Chul; Wurtz, Olivier; Coulouarn, Cédric; Maraver, Antonio; Aaronson, Stuart A; Cortot, Alexis B; Anouar, Youssef; Grumolato, Luca

Comprehensive map of the regulatory network triggered by MET exon 14 skipping reveals important involvement of the RAS-ERK signaling pathway

MET 14号外显子跳跃触发的调控网络综合图谱揭示了RAS-ERK信号通路的重要作用。

Truong, Marie-José; Pawlak, Geoffrey; Meneboo, Jean-Pascal; Sebda, Shéhérazade; Fernandes, Marie; Figeac, Martin; Elati, Mohamed; Tulasne, David

A coregulatory influence map of glioblastoma heterogeneity and plasticity.

胶质母细胞瘤异质性和可塑性的共调控影响图谱

Bernhard Chloé, Geles Konstantinos, Pawlak Geoffrey, Dhifli Wajdi, Dispot Aurélien, Dusol Jules, Kondratova Maria, Martin Sophie, Messé Mélissa, Reita Damien, Tulasne David, Van Seuningen Isabelle, Entz-Werle Natacha, Ciafrè Silvia Anna, Dontenwill Monique, Elati Mohamed

Derepression of the epithelial transcription factor GRHL2 promotes direct hepatocyte-to-cholangiocyte transdifferentiation

上皮转录因子GRHL2的去抑制促进肝细胞向胆管细胞的直接转分化

Vasseur, Ludivine; Gheeraert, Céline; Dubois-Chevalier, Julie; Very, Ninon; Guille, Loïc; Bou Saleh, Mohamed; Boulet, Clémence; Sobolewski, Cyril; Loyer, Pascal; Berthier, Alexandre; Legrand, Noémie; Corlu, Anne; Gnemmi, Viviane; Lasailly, Guillaume; Leteurtre, Emmanuelle; Galinousky, Dmitry; Bongiovanni, Antonino; Taront, Solenne; Toft, Nicolaj I; Grøntved, Lars; Tulasne, David; Furlan, Alessandro; Ntandja-Wandji, Line Carolle; Staels, Bart; Lefebvre, Philippe; Dubuquoy, Laurent; Eeckhoute, Jérôme

MET variants with activating N-lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation.

在遗传性乳头状肾细胞癌中发现的具有激活 N 叶突变的 MET 变体仍然需要配体刺激

Guérin Célia, Vinchent Audrey, Fernandes Marie, Damour Isabelle, Laratte Agathe, Tellier Rémi, Estevam Gabriella O, Meneboo Jean-Pascal, Villenet Céline, Descarpentries Clotilde, Fraser James S, Figeac Martin, Cortot Alexis B, Rouleau Etienne, Tulasne David

Recording and classifying MET receptor mutations in cancers

记录和分类癌症中的MET受体突变

Guérin, Célia; Tulasne, David

Proteolytic cleavages of MET: the divide-and-conquer strategy of a receptor tyrosine kinase

MET的蛋白水解切割:受体酪氨酸激酶的分而治之策略

Fernandes, Marie; Duplaquet, Leslie; Tulasne, David

Outcome of EGFR-mutated NSCLC patients with MET-driven resistance to EGFR tyrosine kinase inhibitors

MET驱动的EGFR酪氨酸激酶抑制剂耐药的EGFR突变型非小细胞肺癌患者的治疗结果

Baldacci, Simon; Mazieres, Julien; Tomasini, Pascale; Girard, Nicolas; Guisier, Florian; Audigier-Valette, Clarisse; Monnet, Isabelle; Wislez, Marie; Pérol, Maurice; Dô, Pascal; Dansin, Eric; Leduc, Charlotte; Giroux Leprieur, Etienne; Moro-Sibilot, Denis; Tulasne, David; Kherrouche, Zoulika; Labreuche, Julien; Cortot, Alexis B

Tensin-4-Dependent MET Stabilization Is Essential for Survival and Proliferation in Carcinoma Cells

Tensin-4依赖的MET稳定作用对癌细胞的存活和增殖至关重要

Muharram, Ghaffar; Sahgal, Pranshu; Korpela, Taina; De Franceschi, Nicola; Kaukonen, Riina; Clark, Katherine; Tulasne, David; Carpén, Olli; Ivaska, Johanna

Proapoptotic function of the MET tyrosine kinase receptor through caspase cleavage.

MET酪氨酸激酶受体通过caspase裂解发挥促凋亡功能

Tulasne David, Deheuninck Julien, Lourenco Filipe Calheiros, Lamballe Fabienne, Ji Zongling, Leroy Catherine, Puchois Emilie, Moumen Anice, Maina Flavio, Mehlen Patrick, Fafeur Véronique