日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Ethanol metabolism by alcohol dehydrogenase or cytochrome P(450) 2E1 differentially impairs hepatic protein trafficking and growth hormone signaling

乙醇通过乙醇脱氢酶或细胞色素P(450) 2E1代谢,对肝脏蛋白质运输和生长激素信号传导的影响存在差异。

Doody, Erin E; Groebner, Jennifer L; Walker, Jetta R; Frizol, Brittnee M; Tuma, Dean J; Fernandez, David J; Tuma, Pamela L

Prolonged feeding with guanidinoacetate, a methyl group consumer, exacerbates ethanol-induced liver injury

长期摄入胍基乙酸(一种甲基消耗剂)会加剧乙醇引起的肝损伤。

Osna, Natalia A; Feng, Dan; Ganesan, Murali; Maillacheruvu, Priya F; Orlicky, David J; French, Samuel W; Tuma, Dean J; Kharbanda, Kusum K

Acetaldehyde Disrupts Interferon Alpha Signaling in Hepatitis C Virus-Infected Liver Cells by Up-Regulating USP18

乙醛通过上调USP18来干扰丙型肝炎病毒感染肝细胞中的干扰素α信号传导

Ganesan, Murali; Poluektova, Larisa Y; Tuma, Dean J; Kharbanda, Kusum K; Osna, Natalia A

Malondialdehyde-acetaldehyde adducts and anti-malondialdehyde-acetaldehyde antibodies in rheumatoid arthritis

类风湿性关节炎中的丙二醛-乙醛加合物和抗丙二醛-乙醛抗体

Thiele, Geoffrey M; Duryee, Michael J; Anderson, Daniel R; Klassen, Lynell W; Mohring, Stephen M; Young, Kathleen A; Benissan-Messan, Dathe; Sayles, Harlan; Dusad, Anand; Hunter, Carlos D; Sokolove, Jeremy; Robinson, William H; O'Dell, James R; Nicholas, Anthony P; Tuma, Dean J; Mikuls, Ted R

Relaxin decreases the severity of established hepatic fibrosis in mice

松弛素可减轻小鼠已形成的肝纤维化的严重程度。

Bennett, Robert G; Heimann, Dean G; Singh, Sudhir; Simpson, Ronda L; Tuma, Dean J

Alcohol-induced defects in hepatic transcytosis may be explained by impaired dynein function

酒精引起的肝脏转胞吞作用缺陷可能与动力蛋白功能受损有关。

Groebner, Jennifer L; Fernandez, David J; Tuma, Dean J; Tuma, Pamela L

Rab GTPases associate with isolated lipid droplets (LDs) and show altered content after ethanol administration: potential role in alcohol-impaired LD metabolism

Rab GTP酶与分离的脂滴(LDs)结合,并在乙醇给药后含量发生改变:可能在酒精损害的脂滴代谢中发挥作用

Rasineni, Karuna; McVicker, Benita L; Tuma, Dean J; McNiven, Mark A; Casey, Carol A

Lysine acetylation induced by chronic ethanol consumption impairs dynamin-mediated clathrin-coated vesicle release

慢性乙醇摄入诱导的赖氨酸乙酰化会损害动力蛋白介导的网格蛋白包被囊泡释放。

Shepard, Blythe D; Tuma, Dean J; Tuma, Pamela L

Malondialdehyde-acetaldehyde-adducted protein inhalation causes lung injury

吸入丙二醛-乙醛加合物蛋白会导致肺损伤

Wyatt, Todd A; Kharbanda, Kusum K; McCaskill, Michael L; Tuma, Dean J; Yanov, Daniel; DeVasure, Jane; Sisson, Joseph H

Betaine treatment attenuates chronic ethanol-induced hepatic steatosis and alterations to the mitochondrial respiratory chain proteome

甜菜碱治疗可减轻慢性乙醇引起的肝脂肪变性及线粒体呼吸链蛋白质组的改变。

Kharbanda, Kusum K; Todero, Sandra L; King, Adrienne L; Osna, Natalia A; McVicker, Benita L; Tuma, Dean J; Wisecarver, James L; Bailey, Shannon M