日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Methaneseleninic acid, a circadian-modulating agent, reactivates latent HIV-1 infection without cellular activation or proliferation.

甲硒酸是一种昼夜节律调节剂,它能重新激活潜伏的 HIV-1 感染,而无需细胞活化或增殖。

Stern Jared, Shepherd Rory A, Kim Youry, Tumpach Carolin, Amos Kirsten E, Williams Oscar H Lloyd, Varshney Swati, King Hannah A D, Rhodes Ajantha, Lewin Sharon R, Roche Michael

The effect of combining HIV latency reversal with inhibition of phosphoinositide-3 kinases or B-cell lymphoma-2 on the HIV reservoir

将逆转 HIV 潜伏期与抑制磷脂酰肌醇-3 激酶或 B 细胞淋巴瘤-2 联合使用对 HIV 病毒库的影响

Kim, Youry; Anderson, Jenny L; Tumpach, Carolin; Solomon, Ajantha; Ong, Jesslyn; Tanaka, Kiho; Zerbato, Jennifer M; Tan, Tania; Teh, Charis E; Gray, Daniel H D; Arandjelovic, Philip; McMahon, James; Meagher, Niamh; Price, David; Pellegrini, Marc; Roche, Michael; Lewin, Sharon R

Targeting Ikaros and Aiolos with pomalidomide fails to reactivate or induce apoptosis of the latent HIV reservoir

使用泊马度胺靶向 Ikaros 和 Aiolos 无法重新激活或诱导潜伏 HIV 库的凋亡

Rachel D Pascoe,Youry Kim,Ajantha Rhodes,Jesslyn Ong,Carolin Tumpach,Celine Gubser,J Judy Chang,James H McMahon,Sharon R Lewin # ,Thomas A Rasmussen #

Hepatitis B surface antigen is upregulated by HIV Tat in an HIV-hepatitis B virus co-infection model system.

在 HIV-乙型肝炎病毒共感染模型系统中,乙型肝炎表面抗原受 HIV Tat 上调

Zhao Wei, Singh Kasha, Sozzi Vitini, Cevaal Paula, Rossello Fernando J, Martelotto Luciano, Zerbato Jennifer M, Rhodes Ajantha, Powell David R, Schröder Jan, Anderson Jenny, Tumpach Carolin, Fong Danielle, Revill Peter, Crane Megan, Grimmond Sean, Roche Michael, Audsley Jennifer, Lewin Sharon R

HIV transcription persists in the brain of virally suppressed people with HIV

HIV 转录在病毒受到抑制的 HIV 感染者大脑中持续存在

Janna Jamal Eddine, Thomas A Angelovich, Jingling Zhou, Sarah J Byrnes, Carolin Tumpach, Nadia Saraya, Emily Chalmers, Rory A Shepherd, Abigail Tan, Stephanie Marinis, Paul R Gorry, Jacob D Estes, Bruce J Brew, Sharon R Lewin, Sushama Telwatte, Michael Roche, Melissa J Churchill

Uncovering strain- and age-dependent innate immune responses to SARS-CoV-2 infection in air-liquid-interface cultured nasal epithelia

揭示气液界面培养鼻上皮中对 SARS-CoV-2 感染的菌株和年龄依赖性先天免疫反应

Jessie J-Y Chang, Samantha L Grimley, Bang M Tran, Georgia Deliyannis, Carolin Tumpach, An N T Nguyen, Eike Steinig, JianShu Zhang, Jan Schröder, Leon Caly, Julie McAuley, Sharon L Wong, Shafagh A Waters, Timothy P Stinear, Miranda E Pitt, Damian Purcell, Elizabeth Vincan, Lachlan J M Coin

Venetoclax, alone and in combination with the BH3 mimetic S63845, depletes HIV-1 latently infected cells and delays rebound in humanized mice

维奈托克(Venetoclax)单独使用或与BH3模拟物S63845联合使用,均可清除人源化小鼠体内潜伏感染的HIV-1细胞并延缓病毒反弹。

Philip Arandjelovic ,Youry Kim ,James P Cooney ,Simon P Preston ,Marcel Doerflinger ,James H McMahon ,Sarah E Garner ,Jennifer M Zerbato ,Michael Roche ,Carolin Tumpach ,Jesslyn Ong ,Dylan Sheerin ,Gordon K Smyth ,Jenny L Anderson ,Cody C Allison ,Sharon R Lewin ,Marc Pellegrini

HIV DNA persists in hepatocytes in people with HIV-hepatitis B co-infection on antiretroviral therapy.

接受抗逆转录病毒治疗的 HIV-乙型肝炎合并感染患者的肝细胞中仍然存在 HIV DNA

Zerbato Jennifer M, Avihingsanon Anchalee, Singh Kasha P, Zhao Wei, Deleage Claire, Rosen Elias, Cottrell Mackenzie L, Rhodes Ajantha, Dantanarayana Ashanti, Tumpach Carolin, Tennakoon Surekha, Crane Megan, Price David J, Braat Sabine, Mason Hugh, Roche Michael, Kashuba Angela D M, Revill Peter A, Audsley Jennifer, Lewin Sharon R

Regional Analysis of Intact and Defective HIV Proviruses in the Brain of Viremic and Virally Suppressed People with HIV

对病毒血症和病毒抑制的HIV感染者脑内完整和缺陷型HIV前病毒进行区域分析

Angelovich, Thomas A; Cochrane, Catherine R; Zhou, Jingling; Tumpach, Carolin; Byrnes, Sarah J; Jamal Eddine, Janna; Waring, Emily; Busman-Sahay, Kathleen; Deleage, Claire; Jenkins, Trisha A; Hearps, Anna C; Turville, Stuart; Gorry, Paul R; Lewin, Sharon R; Brew, Bruce J; Estes, Jacob D; Roche, Michael; Churchill, Melissa J

Adaptation of Droplet Digital PCR-Based HIV Transcription Profiling to Digital PCR and Association of HIV Transcription and Total or Intact HIV DNA

基于液滴数字 PCR 的 HIV 转录分析适应于数字 PCR 以及 HIV 转录与总或完整 HIV DNA 的关联

Carolin Tumpach, Ajantha Rhodes, Youry Kim, Jesslyn Ong, Haoming Liu, Doris Chibo, Julian Druce, Deborah Williamson, Rebecca Hoh, Steven G Deeks, Steven A Yukl, Michael Roche, Sharon R Lewin, Sushama Telwatte