日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The PPARβ/Delta-Induced Mesenchymal Stromal Cell Secretome Has Cytoprotective Effects via ANGPTL4 in a Pre-Clinical Model of Acute Lung Inflammation

PPARβ/Delta诱导的间充质基质细胞分泌组通过ANGPTL4在急性肺部炎症的临床前模型中发挥细胞保护作用

Tunstead, Courteney; Dunlop, Molly; Ryan, Sinéad; Volkova, Evelina; Johnston, Evangeline; Batah, Sabrina; Dos Santos, Claudia C; McNicholas, Bairbre; Masterson, Claire; Laffey, John G; English, Karen

Palmitate enhances MSC immunomodulation of human macrophages via the ceramide/CCL2 axis in vitro

棕榈酸酯通过神经酰胺/CCL2轴增强间充质干细胞对人巨噬细胞的体外免疫调节作用

Tunstead, Courteney; Bitterlich, Laura M; Ankrum, James A; Hogan, Andrew E; English, Karen

The VEGF-Mediated Cytoprotective Ability of MIF-Licensed Mesenchymal Stromal Cells in House Dust Mite-Induced Epithelial Damage

MIF激活的间充质基质细胞通过VEGF介导的细胞保护作用对抗屋尘螨引起的上皮损伤

Dunbar, Hazel; Hawthorne, Ian J; Tunstead, Courteney; Dunlop, Molly; Volkova, Evelina; Weiss, Daniel J; Santos, Claudia C Dos; Armstrong, Michelle E; Donnelly, Seamas C; English, Karen

The ARDS microenvironment enhances MSC-induced repair via VEGF in experimental acute lung inflammation

ARDS微环境通过VEGF增强MSC诱导的修复,从而促进实验性急性肺部炎症。

Tunstead, Courteney; Volkova, Evelina; Dunbar, Hazel; Hawthorne, Ian J; Bell, Alison; Crowe, Louise; Masterson, Joanne C; Dos Santos, Claudia C; McNicholas, Bairbre; Laffey, John G; English, Karen

Human macrophage migration inhibitory factor potentiates mesenchymal stromal cell efficacy in a clinically relevant model of allergic asthma

人巨噬细胞迁移抑制因子可增强间充质基质细胞在临床相关过敏性哮喘模型中的疗效

Hawthorne, Ian J; Dunbar, Hazel; Tunstead, Courteney; Schorpp, Tamara; Weiss, Daniel J; Enes, Sara Rolandsson; Dos Santos, Claudia C; Armstrong, Michelle E; Donnelly, Seamas C; English, Karen

Non invasive imaging assessment of the biodistribution of GSK2849330, an ADCC and CDC optimized anti HER3 mAb, and its role in tumor macrophage recruitment in human tumor-bearing mice

对 GSK2849330(一种 ADCC 和 CDC 优化的抗 HER3 mAb)的生物分布及其在人类肿瘤小鼠中肿瘤巨噬细胞募集的作用进行无创成像评估

Hasan Alsaid, Tinamarie Skedzielewski, Mary V Rambo, Kristen Hunsinger, Bao Hoang, William Fieles, Edward R Long, James Tunstead, Danielle J Vugts, Matthew Cleveland, Neil Clarke, Christopher Matheny, Beat M Jucker

Novel Bispecific Domain Antibody to LRP6 Inhibits Wnt and R-spondin Ligand-Induced Wnt Signaling and Tumor Growth

新型 LRP6 双特异性结构域抗体可抑制 Wnt 和 R-spondin 配体诱导的 Wnt 信号传导和肿瘤生长

Heather Jackson, David Granger, Gavin Jones, Louisa Anderson, Sarah Friel, Daniel Rycroft, William Fieles, James Tunstead, Michael Steward, Trevor Wattam, Adam Walker, Jeremy Griggs, Muhammad Al-Hajj, Christopher Shelton

Inhibition of FGF/FGFR autocrine signaling in mesothelioma with the FGF ligand trap, FP-1039/GSK3052230

使用 FGF 配体陷阱 FP-1039/GSK3052230 抑制间皮瘤中的 FGF/FGFR 自分泌信号传导

Christina Blackwell, Christian Sherk, Maggie Fricko, Gopinath Ganji, Mary Barnette, Bao Hoang, James Tunstead, Tina Skedzielewski, Hasan Alsaid, Beat M Jucker, Elisabeth Minthorn, Rakesh Kumar, M Phillip DeYoung

Novel anti-B-cell maturation antigen antibody-drug conjugate (GSK2857916) selectively induces killing of multiple myeloma

新型抗B细胞成熟抗原抗体药物偶联物(GSK2857916)选择性诱导多发性骨髓瘤细胞死亡

Tai, Yu-Tzu; Mayes, Patrick A; Acharya, Chirag; Zhong, Mike Y; Cea, Michele; Cagnetta, Antonia; Craigen, Jenny; Yates, John; Gliddon, Louise; Fieles, William; Hoang, Bao; Tunstead, James; Christie, Amanda L; Kung, Andrew L; Richardson, Paul; Munshi, Nikhil C; Anderson, Kenneth C

Cardioprotection by systemic dosing of thymosin beta four following ischemic myocardial injury

缺血性心肌损伤后全身应用胸腺素β4发挥心脏保护作用

Bao, Weike; Ballard, Victoria L; Needle, Saul; Hoang, Bao; Lenhard, Stephen C; Tunstead, James R; Jucker, Beat M; Willette, Robert N; Pipes, G Teg