Improved Natural Killer cell activity and retained anti-tumor CD8(+) T cell responses contribute to the induction of a pathological complete response in HER2-positive breast cancer patients undergoing neoadjuvant chemotherapy
增强的自然杀伤细胞活性和保留的抗肿瘤CD8(+) T细胞反应有助于诱导接受新辅助化疗的HER2阳性乳腺癌患者达到病理完全缓解。
期刊:Journal of Translational Medicine
影响因子:7.5
doi:10.1186/s12967-015-0567-0
Muraro, E; Comaro, E; Talamini, R; Turchet, E; Miolo, G; Scalone, S; Militello, L; Lombardi, D; Spazzapan, S; Perin, T; Massarut, S; Crivellari, D; Dolcetti, Riccardo; Martorelli, D
肿瘤
T细胞
HER2
肿瘤免疫
乳腺癌
CD8
T细胞
自然杀伤细胞
细胞生物学
免疫/内分泌