Affinity Maturation of B7-H6 Translates into Enhanced NK Cell-Mediated Tumor Cell Lysis and Improved Proinflammatory Cytokine Release of Bispecific Immunoligands via NKp30 Engagement
B7-H6 的亲和力成熟转化为增强的 NK 细胞介导的肿瘤细胞裂解,并通过 NKp30 结合改善双特异性免疫配体的促炎细胞因子释放
期刊:Journal of Immunology
影响因子:3.6
doi:10.4049/jimmunol.2001004
Lukas Pekar, Katja Klausz, Michael Busch, Bernhard Valldorf, Harald Kolmar, Daniela Wesch, Hans-Heinrich Oberg, Steffen Krohn, Ammelie Svea Boje, Carina Lynn Gehlert, Lars Toleikis, Simon Krah, Tushar Gupta, Brian Rabinovich, Stefan Zielonka, Matthias Peipp