日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Human PXR Signaling Exacerbates Ethanol-induced Liver Injury in Females: Evidence From Mouse Models and Human Alcohol-associated Liver Disease Cohorts

人类PXR信号通路加剧女性乙醇诱导的肝损伤:来自小鼠模型和人类酒精相关肝病队列的证据

Ofosu-Boateng, Malvin; Choi, Sora; Kim, Sarah; Twum, Elizabeth; Nnamani, Daniel O; Gebreyesus, Lidya H; Niture, Suryakant; Yadak, Nour; Kumar, Deepak; Gonzalez, Frank J; Liangpunsakul, Suthat; Cui, Julia Yue; Gyamfi, Maxwell A

Blockade of the estrogen receptor alpha-pregnane X receptor axis protects ovariectomized mice against ethanol-induced hepatotoxicity.

阻断雌激素受体α-孕烷X受体轴可保护卵巢切除小鼠免受乙醇引起的肝毒性

Twum Elizabeth, Ofosu-Boateng Malvin, Nnamani Daniel O, Gebreyesus Lidya H, Yadak Nour, Kharbanda Kusum K, Gonzalez Frank J, Gyamfi Maxwell A

Molecular targets of PXR-dependent ethanol-induced hepatotoxicity in female mice

雌性小鼠PXR依赖性乙醇诱导肝毒性的分子靶点

Choi, Sora; Ofosu-Boateng, Malvin; Kim, Sarah; Nnamani, Daniel O; Mah'moud, Mia; Neequaye, Prince; Gebreyesus, Lidya H; Twum, Elizabeth; Gonzalez, Frank J; Yue Cui, Julia; Gyamfi, Maxwell A

High-fat diet induced obesity promotes inflammation, oxidative stress, and hepatotoxicity in female FVB/N mice.

高脂饮食诱导的肥胖会促进雌性 FVB/N 小鼠的炎症、氧化应激和肝毒性

Ofosu-Boateng Malvin, Shaik Fathima, Choi Sora, Ekuban Frederick A, Gebreyesus Lidya H, Twum Elizabeth, Nnamani Daniel O, Yeyeodu Susan T, Yadak Nour, Collier Daniel M, Gyamfi Maxwell A

BReast CAncer susceptibility gene 2 deficiency exacerbates oxidized LDL-induced DNA damage and endothelial apoptosis

乳腺癌易感基因 2 缺乏加剧氧化 LDL 诱导的 DNA 损伤和内皮细胞凋亡

Shweta Singh, Hien Nguyen, David Michels, Hannah Bazinet, Pratiek N Matkar, Zongyi Liu, Lilian Esene, Mohamed Adam, Antoinette Bugyei-Twum, Elizabeth Mebrahtu, Jameela Joseph, Mehroz Ehsan, Hao H Chen, Mohammad Qadura, Krishna K Singh