日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Small Molecule Functional Converter of B-Cell Lymphoma-2 (Bcl-2) Suppresses Breast Cancer Lung Metastasis.

B细胞淋巴瘤-2 (Bcl-2) 小分子功能转化剂抑制乳腺癌肺转移

期刊:ACS Pharmacology and Translational Science
影响因子:3.7
doi:10.1021/acsptsci.3c00360
Kopparapu Prasad R, Löhr Christiane V, Pearce Martin C, Tyavanagimatt Shanthakumar, Nakshatri Harikrishna, Kolluri Siva K
细胞生物学
乳腺癌
淋巴瘤
肿瘤免疫
发表日期：2024
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Pacritinib is a potent ACVR1 inhibitor with significant anemia benefit in patients with myelofibrosis

帕克替尼是一种强效的ACVR1抑制剂，可显著改善骨髓纤维化患者的贫血症状。

期刊:Blood Advances
影响因子:7.1
doi:10.1182/bloodadvances.2023010151
Oh, Stephen T; Mesa, Ruben A; Harrison, Claire N; Bose, Prithviraj; Gerds, Aaron T; Gupta, Vikas; Scott, Bart L; Kiladjian, Jean-Jacques; Lucchesi, Alessandro; Kong, Tim; Buckley, Sarah A; Tyavanagimatt, Shanthakumar; Harder, Bryan G; Roman-Torres, Karisse; Smith, Jennifer; Craig, Adam R; Mascarenhas, John; Verstovsek, Srdan
贫血
代谢
发表日期：2023
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Determining the recommended dose of pacritinib: results from the PAC203 dose-finding trial in advanced myelofibrosis

确定帕克替尼的推荐剂量：PAC203剂量探索试验在晚期骨髓纤维化中的结果

期刊:Blood Advances
影响因子:7.1
doi:10.1182/bloodadvances.2020003314
Gerds, Aaron T; Savona, Michael R; Scott, Bart L; Talpaz, Moshe; Egyed, Miklos; Harrison, Claire N; Yacoub, Abdulraheem; Vannucchi, Alessandro; Mead, Adam J; Kiladjian, Jean-Jacques; O'Sullivan, Jennifer; García-Gutiérrez, Valentin; Bose, Prithviraj; Rampal, Raajit K; Miller, Carole B; Palmer, Jeanne; Oh, Stephen T; Buckley, Sarah A; Mould, Diane R; Ito, Kaori; Tyavanagimatt, Shanthakumar; Smith, Jennifer A; Roman-Torres, Karisse; Devineni, Sri; Craig, Adam R; Mascarenhas, John O
发表日期：2020
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A potent Lassa virus antiviral targets an arenavirus virulence determinant

一种强效的拉沙病毒抗病毒药物靶向沙粒病毒的毒力决定因子。

期刊:PLoS Pathogens
影响因子:4.9
doi:10.1371/journal.ppat.1007439
Madu, Ikenna G; Files, Megan; Gharaibeh, Dima N; Moore, Amy L; Jung, Kie-Hoon; Gowen, Brian B; Dai, Dongcheng; Jones, Kevin F; Tyavanagimatt, Shanthakumar R; Burgeson, James R; Korth, Marcus J; Bedard, Kristin M; Iadonato, Shawn P; Amberg, Sean M
微生物学
发表日期：2018
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Pharmacokinetic and pharmacodynamic modeling to determine the dose of ST-246 to protect against smallpox in humans

利用药代动力学和药效学模型确定ST-246在人体中预防天花感染的剂量

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.00959-12
Leeds, Janet M; Fenneteau, Frederique; Gosselin, Nathalie H; Mouksassi, Mohamad-Samer; Kassir, Nastya; Marier, J F; Chen, Yali; Grosenbach, Doug; Frimm, Annie E; Honeychurch, Kady M; Chinsangaram, Jarasvech; Tyavanagimatt, Shanthakumar R; Hruby, Dennis E; Jordan, Robert
炎症/感染
发表日期：2013
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Safety and pharmacokinetics of the anti-orthopoxvirus compound ST-246 following a single daily oral dose for 14 days in human volunteers

在人体志愿者中，每日单次口服抗正痘病毒化合物ST-246，连续14天，其安全性和药代动力学研究

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.00904-12
Chinsangaram, Jarasvech; Honeychurch, Kady M; Tyavanagimatt, Shanthakumar R; Leeds, Janet M; Bolken, Tove' C; Jones, Kevin F; Jordan, Robert; Marbury, Thomas; Ruckle, Jon; Mee-Lee, Denis; Ross, Eric; Lichtenstein, Israel; Pickens, Margaret; Corrado, Michael; Clarke, Jean M; Frimm, Annie M; Hruby, Dennis E
微生物学
发表日期：2012
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Pharmacokinetic comparison of a single oral dose of polymorph form i versus form V capsules of the antiorthopoxvirus compound ST-246 in human volunteers

在人体志愿者中比较单次口服抗正痘病毒化合物ST-246的多晶型i型胶囊与V型胶囊的药代动力学

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.06090-11
Chinsangaram, Jarasvech; Honeychurch, Kady M; Tyavanagimatt, Shanthakumar R; Bolken, Tove' C; Jordan, Robert; Jones, Kevin F; Marbury, Thomas; Lichtenstein, Israel; Pickens, Margaret; Corrado, Michael; Landis, Patrick; Clarke, Jean M; Frimm, Annie M; Hruby, Dennis E
微生物学
发表日期：2012
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Comparison of the safety and pharmacokinetics of ST-246® after i.v. infusion or oral administration in mice, rabbits and monkeys

比较小鼠、兔和猴静脉输注或口服ST-246®后的安全性和药代动力学

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0023237
Chen, Yali; Amantana, Adams; Tyavanagimatt, Shanthakumar R; Zima, Daniela; Yan, X Steven; Kasi, Gopi; Weeks, Morgan; Stone, Melialani A; Weimers, William C; Samuel, Peter; Tan, Ying; Jones, Kevin F; Lee, Daniel R; Kickner, Shirley S; Saville, Bradley M; Lauzon, Martin; McIntyre, Alan; Honeychurch, Kady M; Jordan, Robert; Hruby, Dennis E; Leeds, Janet M
发表日期：2011
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Safety and pharmacokinetics of the antiorthopoxvirus compound ST-246 following repeat oral dosing in healthy adult subjects

健康成年受试者重复口服抗正痘病毒化合物ST-246后的安全性和药代动力学

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.01689-09
Jordan, Robert; Chinsangaram, Jarasvech; Bolken, Tove' C; Tyavanagimatt, Shanthakumar R; Tien, Deborah; Jones, Kevin F; Frimm, Annie; Corrado, Michael L; Pickens, Margaret; Landis, Patrick; Clarke, Jean; Marbury, Thomas C; Hruby, Dennis E
微生物学
发表日期：2010
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Development of ST-246® for Treatment of Poxvirus Infections

ST-246® 的研发及其在痘病毒感染治疗中的应用

期刊:Viruses-Basel
影响因子:3.5
doi:10.3390/v2112409
Jordan, Robert; Leeds, Janet M; Tyavanagimatt, Shanthakumar; Hruby, Dennis E
炎症/感染
微生物学
发表日期：2010
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