日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Transcript Analysis Reveals a Hypoxic Inflammatory Environment in Human Chronic Otitis Media With Effusion

转录组分析揭示人类慢性渗出性中耳炎中存在缺氧炎症环境

Bhutta, Mahmood F; Lambie, Jane; Hobson, Lindsey; Williams, Debbie; Tyrer, Hayley E; Nicholson, George; Brown, Steve D M; Brown, Helen; Piccinelli, Chiara; Devailly, Guillaume; Ramsden, James; Cheeseman, Michael T

Albendazole and antibiotics synergize to deliver short-course anti-Wolbachia curative treatments in preclinical models of filariasis

阿苯达唑和抗生素具有协同作用,可在丝虫病临床前模型中提供短期抗沃尔巴克氏体治愈性治疗。

Turner, Joseph D; Sharma, Raman; Al Jayoussi, Ghaith; Tyrer, Hayley E; Gamble, Joanne; Hayward, Laura; Priestley, Richard S; Murphy, Emma A; Davies, Jill; Waterhouse, David; Cook, Darren A N; Clare, Rachel H; Cassidy, Andrew; Steven, Andrew; Johnston, Kelly L; McCall, John; Ford, Louise; Hemingway, Janet; Ward, Stephen A; Taylor, Mark J

Short-Course, High-Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis

短期高剂量利福平治疗可使沃尔巴克氏体耗竭,这可预测淋巴丝虫病和盘尾丝虫病临床前模型的治愈结果。

Aljayyoussi, Ghaith; Tyrer, Hayley E; Ford, Louise; Sjoberg, Hanna; Pionnier, Nicolas; Waterhouse, David; Davies, Jill; Gamble, Joanne; Metuge, Haelly; Cook, Darren A N; Steven, Andrew; Sharma, Raman; Guimaraes, Ana F; Clare, Rachel H; Cassidy, Andrew; Johnston, Kelly L; Myhill, Laura; Hayward, Laura; Wanji, Samuel; Turner, Joseph D; Taylor, Mark J; Ward, Stephen A

A mutation in Nischarin causes otitis media via LIMK1 and NF-κB pathways.

Nischarin 基因突变通过 LIMK1 和 NF-κB 通路引起中耳炎

Crompton Michael, Purnell Tom, Tyrer Hayley E, Parker Andrew, Ball Greg, Hardisty-Hughes Rachel E, Gale Richard, Williams Debbie, Dean Charlotte H, Simon Michelle M, Mallon Ann-Marie, Wells Sara, Bhutta Mahmood F, Burton Martin J, Tateossian Hilda, Brown Steve D M

Minocycline as a re-purposed anti-Wolbachia macrofilaricide: superiority compared with doxycycline regimens in a murine infection model of human lymphatic filariasis

米诺环素作为一种重新利用的抗沃尔巴克氏体成虫杀灭剂:在人淋巴丝虫病小鼠感染模型中优于多西环素方案。

Sharma, Raman; Al Jayoussi, Ghaith; Tyrer, Hayley E; Gamble, Joanne; Hayward, Laura; Guimaraes, Ana F; Davies, Jill; Waterhouse, David; Cook, Darren A N; Myhill, Laura J; Clare, Rachel H; Cassidy, Andrew; Steven, Andrew; Johnston, Kelly L; Ford, Louise; Turner, Joseph D; Ward, Stephen A; Taylor, Mark J

A murine macrofilaricide pre-clinical screening model for onchocerciasis and lymphatic filariasis

用于盘尾丝虫病和淋巴丝虫病的鼠类杀丝虫剂临床前筛选模型

Halliday, Alice; Guimaraes, Ana F; Tyrer, Hayley E; Metuge, Haelly Mejane; Patrick, Chounna Ndongmo Winston; Arnaud, Kengne-Ouafo Jonas; Kwenti, Tayong Dizzle Bita; Forsbrook, George; Steven, Andrew; Cook, Darren; Enyong, Peter; Wanji, Samuel; Taylor, Mark J; Turner, Joseph D