Tyrrell D Lorne相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Recombinant H77C gpE1/gpE2 heterodimer elicits superior HCV cross-neutralisation than H77C gpE2 alone

重组H77C gpE1/gpE2异二聚体比单独的H77C gpE2具有更强的HCV交叉中和能力。

期刊:Journal of Hepatology

影响因子:33

doi:10.1016/j.jhep.2024.06.029

Kundu, Juthika; Le, Hoa T; Logan, Michael; Hockman, Darren; Landi, Abdolamir; Crawford, Kevin; Wininger, Mark; Johnson, Janelle; Kundu, Joydeb K; Tiffney, E Alana; Urbanowicz, Richard A; Ball, Jonathan K; Bailey, Justin R; Bukh, Jens; Law, Mansun; Foung, Steven; Tyrrell, D Lorne; Houghton, Michael; Law, John Lokman

发表日期：2024

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Peptide Aldehydes Incorporating Thiazol-4-yl Alanine Are Potent In Vitro Inhibitors of SARS-CoV-2 Main Protease

含有噻唑-4-基丙氨酸的肽醛是SARS-CoV-2主蛋白酶的强效体外抑制剂

期刊:ACS Medicinal Chemistry Letters

doi:10.1021/acsmedchemlett.4c00444

Feys, Jenson R; Edwards, Kyle; Joyce, Michael A; Saffran, Holly A; Shields, Justin A; Garcia, Kassandra; Tyrrell, D Lorne; Fischer, Conrad

发表日期：2024

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A phase 1 randomized controlled trial of a peptide-based group A streptococcal vaccine in healthy volunteers

一项针对健康志愿者的基于肽的A组链球菌疫苗的1期随机对照试验

doi:10.1186/s13063-024-08634-4

Meier-Stephenson, Vanessa; Hawkes, Michael T; Burton, Catherine; Calcutt, Ainslie; Davis, Chris; Dooley, Jessica; Good, Michael; Houghton, Michael; Keeffe, Eloise; Kim, Kelly; Lepletier, Ailin; O'Neil, Conar; Ogbuehi, Ijeoma; Ozberk, Victoria; Pandey, Manisha; Reynolds, Simone; Seth, Avi; Stokes, William; Tse-Chang, Alena; Tyrrell, Ben; Tyrrell, D Lorne; Tyrrell, Gregory J; Yaskina, Maryna

发表日期：2024

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Challenge Inoculum for Hepatitis C Virus Controlled Human Infection Model

丙型肝炎病毒控制性人体感染模型的挑战接种物

期刊:Clinical Infectious Diseases

影响因子:7.3

doi:10.1093/cid/ciad336

Liang, T Jake; Law, John L M; Pietschmann, Thomas; Ray, Stuart C; Bukh, Jens; Bull, Rowena; Chung, Raymond T; Tyrrell, D Lorne; Houghton, Michael; Rice, Charles M

发表日期：2023

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The Effect of Deuteration and Homologation of the Lactam Ring of Nirmatrelvir on Its Biochemical Properties and Oxidative Metabolism

尼尔马特雷韦内酰胺环的氘代和同系化对其生化特性和氧化代谢的影响

期刊:ACS Bio & Med Chem Au

影响因子:4.3

doi:10.1021/acsbiomedchemau.3c00039

Arutyunova, Elena; Belovodskiy, Alexandr; Chen, Pu; Khan, Muhammad Bashir; Joyce, Michael; Saffran, Holly; Lu, Jimmy; Turner, Zoe; Bai, Bing; Lamer, Tess; Young, Howard S; Vederas, John C; Tyrrell, D Lorne; Lemieux, M Joanne; Nieman, James A

发表日期：2023

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Differential Impact of SARS-CoV-2 Isolates, Namely, the Wuhan Strain, Delta, and Omicron Variants on Erythropoiesis

SARS-CoV-2 分离株（即武汉株、Delta 变异株和 Omicron 变异株）对红细胞生成的不同影响

期刊:Microbiology Spectrum

影响因子:3.8

doi:10.1128/spectrum.01730-22

Saito, Suguru; Shahbaz, Shima; Sligl, Wendy; Osman, Mohammed; Tyrrell, D Lorne; Elahi, Shokrollah

细胞生物学

发表日期：2022

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CRISPR technology incorporating amplification strategies: molecular assays for nucleic acids, proteins, and small molecules

结合扩增策略的CRISPR技术：用于核酸、蛋白质和小分子的分子检测

期刊:Chemical Science

影响因子:7.4

doi:10.1039/d0sc06973f

Feng, Wei; Newbigging, Ashley M; Tao, Jeffrey; Cao, Yiren; Peng, Hanyong; Le, Connie; Wu, Jinjun; Pang, Bo; Li, Juan; Tyrrell, D Lorne; Zhang, Hongquan; Le, X Chris

发表日期：2021

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Erythroid precursors and progenitors suppress adaptive immunity and get invaded by SARS-CoV-2

红系前体细胞和祖细胞会抑制适应性免疫，并容易受到SARS-CoV-2病毒的入侵。

期刊:Stem Cell Reports

影响因子:5.1

doi:10.1016/j.stemcr.2021.04.001

Shahbaz, Shima; Xu, Lai; Osman, Mohammed; Sligl, Wendy; Shields, Justin; Joyce, Michael; Tyrrell, D Lorne; Oyegbami, Olaide; Elahi, Shokrollah

细胞生物学

免疫/内分泌

发表日期：2021

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Author Correction: Feline coronavirus drug inhibits the main protease of SARS-CoV-2 and blocks virus replication

作者更正：猫冠状病毒药物抑制SARS-CoV-2的主要蛋白酶并阻断病毒复制。

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-020-19339-y

Vuong, Wayne; Khan, Muhammad Bashir; Fischer, Conrad; Arutyunova, Elena; Lamer, Tess; Shields, Justin; Saffran, Holly A; McKay, Ryan T; van Belkum, Marco J; Joyce, Michael A; Young, Howard S; Tyrrell, D Lorne; Vederas, John C; Lemieux, M Joanne

发表日期：2020

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In Vitro Hepatitis C Virus Infection and Hepatic Choline Metabolism

体外丙型肝炎病毒感染与肝脏胆碱代谢

期刊:Viruses-Basel

影响因子:3.5

doi:10.3390/v12010108

Gobeil Odai, Kaelan; O'Dwyer, Conor; Steenbergen, Rineke; Shaw, Tyler A; Renner, Tyler M; Ghorbani, Peyman; Rezaaifar, Mojgan; Han, Shauna; Langlois, Marc-André; Crawley, Angela M; Russell, Rodney S; Pezacki, John P; Tyrrell, D Lorne; Fullerton, Morgan D

发表日期：2020

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