Mitochondrial superoxide mediates doxorubicin-induced keratinocyte apoptosis through oxidative modification of ERK and Bcl-2 ubiquitination
线粒体超氧化物通过氧化修饰ERK和Bcl-2泛素化介导阿霉素诱导的角质形成细胞凋亡。
期刊:Biochemical Pharmacology
影响因子:5.6
doi:10.1016/j.bcp.2012.03.010
Luanpitpong, Sudjit; Chanvorachote, Pithi; Nimmannit, Ubonthip; Leonard, Stephen S; Stehlik, Christian; Wang, Liying; Rojanasakul, Yon
Bcl-2
凋亡
表观遗传
泛素化
MAPK/ERK
线粒体
细胞生物学