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Cryo-EM structures and binding of mouse and human ACE2 to SARS-CoV-2 variants of concern indicate that mutations enabling immune escape could expand host range

冷冻电镜结构分析表明，小鼠和人ACE2与SARS-CoV-2相关变种的结合情况表明，能够使病毒免疫逃逸的突变可能会扩大其宿主范围。

doi:10.1371/journal.ppat.1011206

Ni, Dongchun; Turelli, Priscilla; Beckert, Bertrand; Nazarov, Sergey; Uchikawa, Emiko; Myasnikov, Alexander; Pojer, Florence; Trono, Didier; Stahlberg, Henning; Lau, Kelvin

Cryo-EM structure of the PlexinC1/A39R complex reveals inter-domain interactions critical for ligand-induced activation.

PlexinC1/A39R复合物的冷冻电镜结构揭示了配体诱导激活所必需的域间相互作用

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-020-15862-0

Kuo Yi-Chun, Chen Hua, Shang Guijun, Uchikawa Emiko, Tian Hui, Bai Xiao-Chen, Zhang Xuewu

其它

发表日期：2020

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Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5

双链RNA与抗病毒模式识别受体LGP2和MDA5结合的结构分析

期刊:Molecular Cell

影响因子:16.6

doi:10.1016/j.molcel.2016.04.021

Uchikawa, Emiko; Lethier, Mathilde; Malet, Hélène; Brunel, Joanna; Gerlier, Denis; Cusack, Stephen

Structural insight into the mechanism of stabilization of the 7SK small nuclear RNA by LARP7

LARP7稳定7SK小核RNA的机制的结构解析

期刊:Nucleic Acids Research

影响因子:13.1

doi:10.1093/nar/gkv173

Uchikawa, Emiko; Natchiar, Kundhavai S; Han, Xiao; Proux, Florence; Roblin, Pierre; Zhang, Elodie; Durand, Alexandre; Klaholz, Bruno P; Dock-Bregeon, Anne-Catherine

发表日期：2015

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Kinetic discrimination of self/non-self RNA by the ATPase activity of RIG-I and MDA5

RIG-I 和 MDA5 的 ATPase 活性对自身/非自身 RNA 进行动力学区分

期刊:BMC Biology

影响因子:4.5

doi:10.1186/s12915-015-0166-9

Louber, Jade; Brunel, Joanna; Uchikawa, Emiko; Cusack, Stephen; Gerlier, Denis

发表日期：2015

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Modeling the structure of RNA molecules with small-angle X-ray scattering data

利用小角X射线散射数据对RNA分子结构进行建模

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0078007

Gajda, Michal Jan; Martinez Zapien, Denise; Uchikawa, Emiko; Dock-Bregeon, Anne-Catherine

发表日期：2013

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Direct Measurement of Protein Pair Interaction Potential

蛋白质对相互作用势的直接测量

Cryo-EM structures and binding of mouse and human ACE2 to SARS-CoV-2 variants of concern indicate that mutations enabling immune escape could expand host range

冷冻电镜结构分析表明，小鼠和人ACE2与SARS-CoV-2相关变种的结合情况表明，能够使病毒免疫逃逸的突变可能会扩大其宿主范围。

Cryo-EM structure of the PlexinC1/A39R complex reveals inter-domain interactions critical for ligand-induced activation.

PlexinC1/A39R复合物的冷冻电镜结构揭示了配体诱导激活所必需的域间相互作用

Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5

双链RNA与抗病毒模式识别受体LGP2和MDA5结合的结构分析

Structural insight into the mechanism of stabilization of the 7SK small nuclear RNA by LARP7

LARP7稳定7SK小核RNA的机制的结构解析

Kinetic discrimination of self/non-self RNA by the ATPase activity of RIG-I and MDA5

RIG-I 和 MDA5 的 ATPase 活性对自身/非自身 RNA 进行动力学区分

Modeling the structure of RNA molecules with small-angle X-ray scattering data

利用小角X射线散射数据对RNA分子结构进行建模