日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Discovery and development of potent and selective dual NUAK/MARK inhibitors as Hippo pathway modulators for the treatment of cancer

发现和开发高效且选择性的双重NUAK/MARK抑制剂,作为Hippo通路调节剂用于癌症治疗

Smil, David; Liu, Yong; Xin, Tao; Kiyota, Taira; Aman, Ahmed; Grouleff, Julie; Hoffer, Laurent; Joshi, Dhananjay C; Inanlou, Mohammad R; Song, Siyuan; Mao, Daniel Y L; Ogunjimi, Abiodun A; Pau, Victor; Chini, Fiona D; Kurinov, Igor; Zhang, Ying; Nguyen, Anh Thu; Wrana, Jeffrey L; Sicheri, Frank; Attisano, Liliana; Uehling, David; Al-Awar, Rima; Isaac, Methvin B

Homogeneous Reductant Facilitated Cross-Electrophile Coupling of Aryl Bromides with NHP Esters

均相还原剂促进芳基溴化物与NHP酯的交叉亲电偶联反应

Kundu, Abhishek; Kim, Seoyeon; Hazari, Nilay; Uehling, Mycah R; Yalla, Raju

A modular synthesis of azetidines from reactive triplet imine intermediates using an intermolecular aza Paternò-Büchi reaction

利用分子间氮杂Paternò-Büchi反应,从活性三线态亚胺中间体模块化合成氮杂环丁烷

Williams, Benedict A; Tilby, Michael J; Parker, Nicholas A; Uehling, Mycah R; Hethcox, J Caleb; Kalyani, Dipannita; Willis, Michael C

OICR-41103 as a chemical probe for the DCAF1 WD40 domain.

OICR-41103 作为 DCAF1 WD40 结构域的化学探针

Kimani Serah W, Noureldin Mahmoud, Wilson Brian, Hoffer Laurent, Green Stuart R, Szewczyk Magdalena M, González-Álvarez Héctor, Mohammed Mohammed, Chan Manuel, Krausser Chiara, Li Alice Shi Ming, Hajian Taraneh, Tucker Sarah, Joshi Dhananjay, Saraon Punit, Thériault Brigitte, Kim Ji Sup, Santhakumar Vijayaratnam, Loppnau Peter, Li Yanjun, Seitova Almagul, Dong Aiping, Kiyota Taira, Hammann Tobias, Gehrtz Paul, Patel Bhashant, Rathod Vaibhavi, Vala Anand, Rout Bhimsen, Jagodra Paras, Brown Peter J, Aman Ahmed, Ramnauth Jailall, Poda Gennady, Uehling David, Arrowsmith Cheryl H, Barsyte-Lovejoy Dalia, Marcellus Richard, Ackloo Suzanne, Mamai Ahmed, Al-Awar Rima, Halabelian Levon

Tomato rot by Rhizopus microsporus alters native fungal community composition and secondary metabolite production

根霉属真菌引起的番茄腐烂会改变本地真菌群落组成和次生代谢产物的产生。

Napo, Mmanoko; Kock, Alicia; Alayande, Kazeem A; Sulyok, Michael; Ezekiel, Chibundu N; Uehling, Jessie; Pawlowska, Teresa E; Adeleke, Rasheed A

The biocontrol potential of endophyte Bacillus velezensis to reduce post-harvest tomato infection caused by Rhizopus microsporus

内生菌贝莱斯芽孢杆菌对减少由小孢根霉引起的番茄采后感染的生物防治潜力

Kock, Alicia; Napo, Mmanoko; Viviers, Dionné; Akinmoladun, Oluwakemi V; Alayande, Kazeem A; Yusuf, Abdullahi; Uehling, Jessie; Pawlowska, Teresa E; Adeleke, Rasheed A

"Select and Resequence" Methods Enable a Genome-Wide Association Study of the Dimorphic Human Fungal Pathogen Coccidioides posadasii

“选择和重测序”方法使得对二态性人类真菌病原体波萨达斯球孢子菌进行全基因组关联研究成为可能。

Voorhies, Mark; Joehnk, Bastian; Uehling, Jessie; Walcott, Keith; Dubin, Claire A; Mead, Heather L; Homer, Christina M; Galgiani, John N; Barker, Bridget M; Brem, Rachel B; Sil, Anita

Divergent climate impacts despite similar response to temperature in a widespread aerial insectivore

尽管一种分布广泛的空中食虫动物对温度的反应相似,但其气候变化的影响却截然不同。

Taff, C C; Shipley, J R; Ardia, D R; Aborn, D; Albert, L; Bélisle, M; Belmaker, A; Berzins, L L; Blake, T; Bonier, F; Brewer, H C; Butler, M W; Cameron, K; Case, S B; Chang van Oordt, D; Clark, R G; Clotfelter, E D; Cox, A R; Dawson, R D; Derryberry, E P; Bohorquez, A M Diaz; Dunn, P O; Ferretti, V; Forsman, A M; Fuirst, M; Garant, D; Garrett, D R; Gutiérrez, J; Hagelin, J C; Hardt, B M; Harris, M E; Horton, K; Houle, C; Houtz, J L; Jones, P L; Jordan, K C; Kindel, A S; Klaver, R; Knutie, S A; Lauck, K S; Lombardo, M P; Lougheed, S C; Love, A C; Mackenzie, S A; McCarty, J P; McKellar, A E; Mejia, N; Morrissey, C A; Nahom, M L; Norris, D R; Para, L M; Pelletier, F; Porter, C K; Rendell, W B; Riddell, E A; Rivers, J W; Robertson, R J; Rose, A; Rosvall, K A; Ryan, T A; Shannon, R P; Shutler, D; Simons, V F; Stanback, M; Tarwater, C E; Thorpe, P A; Tingley, M W; Tischer, C L; Tonelli, B A; Truan, M L; Twining, C W; Uehling, J J; Vleck, C; Vleck, D; Watson, M L; Wheelwright, N T; Whittingham, L A; Winkler, D W; Youngflesh, C; Zimmer, C; Vitousek, M N

Crystal structures of DCAF1-PROTAC-WDR5 ternary complexes provide insight into DCAF1 substrate specificity

DCAF1-PROTAC-WDR5三元复合物的晶体结构揭示了DCAF1的底物特异性

Mark F Mabanglo # ,Brian Wilson # ,Mahmoud Noureldin # ,Serah W Kimani ,Ahmed Mamai ,Chiara Krausser ,Héctor González-Álvarez ,Smriti Srivastava ,Mohammed Mohammed ,Laurent Hoffer ,Manuel Chan ,Jamie Avrumutsoae ,Alice Shi Ming Li ,Taraneh Hajian ,Sarah Tucker ,Stuart Green ,Magdalena Szewczyk ,Dalia Barsyte-Lovejoy ,Vijayaratnam Santhakumar ,Suzanne Ackloo ,Peter Loppnau ,Yanjun Li ,Almagul Seitova ,Taira Kiyota ,Jue George Wang ,Gilbert G Privé ,Douglas A Kuntz ,Bhashant Patel ,Vaibhavi Rathod ,Anand Vala ,Bhimsen Rout ,Ahmed Aman ,Gennady Poda ,David Uehling ,Jailall Ramnauth ,Levon Halabelian ,Richard Marcellus ,Rima Al-Awar ,Masoud Vedadi

Effect of 6,6'-Substituents on Bipyridine-Ligated Ni Catalysts for Cross-Electrophile Coupling

6,6'-取代基对联吡啶配位镍催化剂在交叉亲电偶联反应中的影响

Huang, Haotian; Alvarez-Hernandez, Jose L; Hazari, Nilay; Mercado, Brandon Q; Uehling, Mycah R