Unome相关文献与解析，生知库 | 链接生命科学的每一步

Utakata, Yuki; Miwa, Takao; Unome, Shinji; Masuda, Naoya; Oi, Mikita; Aiba, Masashi; Imai, Kenji; Takai, Koji; Shiraki, Makoto; Katsumura, Naoki; Shimizu, Masahito

肝硬化

发表日期：2026

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Development of overt hepatic encephalopathy increases mortality in patients with cirrhosis: a multicenter retrospective cohort study

显性肝性脑病的发生会增加肝硬化患者的死亡率：一项多中心回顾性队列研究

期刊:Journal of Gastroenterology

影响因子:5.5

doi:10.1007/s00535-025-02309-w

Iwasa, Taisei; Miwa, Takao; Utakata, Yuki; Oi, Mikita; Asakura, Mayu; Onishi, Takumi; Aiba, Masashi; Unome, Shinji; Hanai, Tatsunori; Shiraki, Makoto; Adachi, Seiji; Katsumura, Naoki; Kawashima, Yasuhiro; Nishiwaki, Shinji; Shimizu, Masahito

Clinical Characteristics of Patients With Advanced Hepatocellular Carcinoma Who Transitioned to Subsequent Therapies Following Systemic Therapy

接受全身治疗后转为后续治疗的晚期肝细胞癌患者的临床特征

期刊:Cancer Medicine

影响因子:3.1

doi:10.1002/cam4.71616

Imai, Kenji; Takai, Koji; Aiba, Masashi; Unome, Shinji; Miwa, Takao; Hanai, Tatsunori; Sakai, Hiroyasu; Shirakami, Yohei; Suetsugu, Atsushi; Shimizu, Masahito

Determinants of Skeletal Muscle Preservation in Patients with Chronic Liver Disease

慢性肝病患者骨骼肌保存的决定因素

期刊:JMA Journal

影响因子:1.8

doi:10.31662/jmaj.2025-0292

Aiba, Masashi; Hanai, Tatsunori; Nishimura, Kayoko; Unome, Shinji; Miwa, Takao; Nakahata, Yuki; Imai, Kenji; Suetsugu, Atsushi; Takai, Koji; Shimizu, Masahito

发表日期：2026

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Frailty Diagnosed With the Clinical Frailty Scale Stratifies the Risk of Covert and Overt Hepatic Encephalopathy in Patients With Cirrhosis

采用临床衰弱量表诊断的衰弱程度可对肝硬化患者发生隐性或显性肝性脑病的风险进行分层。

期刊:JGH Open

影响因子:1.5

doi:10.1002/jgh3.70369

Unome, Shinji; Miwa, Takao; Hirata, Sachiyo; Nakashima, Satomi; Nishimura, Kayoko; Oi, Mikita; Aiba, Masashi; Imai, Kenji; Takai, Koji; Shimizu, Masahito

Nutritional assessment using subjective global assessment identifies energy malnutrition and predicts mortality in patients with liver cirrhosis

采用主观整体评估法进行营养评估，可以识别能量营养不良并预测肝硬化患者的死亡率。

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-025-89803-6

Miwa, Takao; Hanai, Tatsunori; Nishimura, Kayoko; Hirata, Sachiyo; Unome, Shinji; Nakahata, Yuki; Imai, Kenji; Suetsugu, Atsushi; Takai, Koji; Shimizu, Masahito

肝硬化

发表日期：2025

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Serum tyrosine level is an independent factor for hepatocellular carcinoma development and mortality in patients with chronic liver disease

血清酪氨酸水平是慢性肝病患者发生肝细胞癌和死亡的独立危险因素。

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-025-21373-z

Oi, Mikita; Miwa, Takao; Utakata, Yuki; Aiba, Masashi; Unome, Shinji; Hanai, Tatsunori; Shiraki, Makoto; Katsumura, Naoki; Kawashima, Yasuhiro; Shimizu, Masahito

Simple scoring model for predicting overt hepatic encephalopathy in geriatric cirrhosis: A multicenter retrospective cohort study

用于预测老年肝硬化患者显性肝性脑病的简易评分模型：一项多中心回顾性队列研究

期刊:Metabolic Brain Disease

影响因子:3.5

doi:10.1007/s11011-025-01691-x

Utakata, Yuki; Miwa, Takao; Aiba, Masashi; Unome, Shinji; Hanai, Tatsunori; Imai, Kenji; Shirakami, Yohei; Takai, Koji; Shiraki, Makoto; Katsumura, Naoki; Shimizu, Masahito

Usefulness of Retinol-Binding Protein in Predicting Mortality in Patients With Chronic Liver Disease

视黄醇结合蛋白在预测慢性肝病患者死亡率中的应用价值

期刊:JGH Open

影响因子:1.5

doi:10.1002/jgh3.70087

Utakata, Yuki; Miwa, Takao; Hanai, Tatsunori; Aiba, Masashi; Unome, Shinji; Imai, Kenji; Shirakami, Yohei; Takai, Koji; Shimizu, Masahito

发表日期：2025

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Acute kidney injury development is associated with mortality in Japanese patients with cirrhosis: impact of amino acid imbalance

急性肾损伤的发生与日本肝硬化患者的死亡率相关：氨基酸失衡的影响

期刊:Journal of Gastroenterology

影响因子:5.5

doi:10.1007/s00535-024-02126-7

Miwa, Takao; Utakata, Yuki; Hanai, Tatsunori; Aiba, Masashi; Unome, Shinji; Imai, Kenji; Takai, Koji; Shiraki, Makoto; Katsumura, Naoki; Shimizu, Masahito

Amino Acid Imbalance Is an Independent Factor for Mortality in Patients With Liver Cirrhosis

氨基酸失衡是肝硬化患者死亡的独立危险因素

Development of overt hepatic encephalopathy increases mortality in patients with cirrhosis: a multicenter retrospective cohort study

显性肝性脑病的发生会增加肝硬化患者的死亡率：一项多中心回顾性队列研究

Clinical Characteristics of Patients With Advanced Hepatocellular Carcinoma Who Transitioned to Subsequent Therapies Following Systemic Therapy

接受全身治疗后转为后续治疗的晚期肝细胞癌患者的临床特征

Determinants of Skeletal Muscle Preservation in Patients with Chronic Liver Disease

慢性肝病患者骨骼肌保存的决定因素

Frailty Diagnosed With the Clinical Frailty Scale Stratifies the Risk of Covert and Overt Hepatic Encephalopathy in Patients With Cirrhosis

采用临床衰弱量表诊断的衰弱程度可对肝硬化患者发生隐性或显性肝性脑病的风险进行分层。

Nutritional assessment using subjective global assessment identifies energy malnutrition and predicts mortality in patients with liver cirrhosis

采用主观整体评估法进行营养评估，可以识别能量营养不良并预测肝硬化患者的死亡率。

Serum tyrosine level is an independent factor for hepatocellular carcinoma development and mortality in patients with chronic liver disease

血清酪氨酸水平是慢性肝病患者发生肝细胞癌和死亡的独立危险因素。

Simple scoring model for predicting overt hepatic encephalopathy in geriatric cirrhosis: A multicenter retrospective cohort study

用于预测老年肝硬化患者显性肝性脑病的简易评分模型：一项多中心回顾性队列研究

Usefulness of Retinol-Binding Protein in Predicting Mortality in Patients With Chronic Liver Disease

视黄醇结合蛋白在预测慢性肝病患者死亡率中的应用价值

Acute kidney injury development is associated with mortality in Japanese patients with cirrhosis: impact of amino acid imbalance

急性肾损伤的发生与日本肝硬化患者的死亡率相关：氨基酸失衡的影响