日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Single-cell profiling reveals that dynamic lung immune responses distinguish protection from susceptibility to tuberculosis

单细胞分析表明,动态的肺部免疫反应能够区分对结核病的保护作用和易感性。

Duffy, Fergal J; Neal, Maxwell L; Plumlee, Courtney R; Cohen, Sara B; Gern, Benjamin H; Diercks, Alan H; Gerner, Michael Y; Urdahl, Kevin B; Aitchison, John D

Early and opposing neutrophil and CD4 T cell responses shape pulmonary tuberculosis pathology.

早期相反的中性粒细胞和 CD4 T 细胞反应塑造了肺结核的病理

Gern Benjamin H, Klas Josepha M, Foster Kimberly A, Kanagy Molly E, Cohen Sara B, Plumlee Courtney R, Duffy Fergal J, Neal Maxwell L, Halima Mehnaz, Gustin Andrew T, Stull Sylvia M, Wilson Jasmine J, Diercks Alan H, Aderem Alan, Gale Michael Jr, Aitchison John D, Gerner Michael Y, Urdahl Kevin B

Mycobacterium tuberculosis growth inhibition by peripheral blood mononuclear cells from household contacts is not affected by previous SARS-CoV-2 infection

家庭接触者外周血单核细胞对结核分枝杆菌生长的抑制作用不受既往SARS-CoV-2感染的影响

Shaw, Jane A; Petersen, Caleb; Hiemstra, Andriette; Meiring, Maynard; Eribo, Osagie A; Otum, Christian; van Rensburg, Ilana; Shabangu, Ayanda; Smith, Bronwyn; Noor, Firdows; Walzl, Gerhard; Urdahl, Kevin B; Lewinsohn, Dave; Malherbe, Stephanus T; du Plessis, Nelita

ESX-5 Deletions in Mycobacterium tuberculosis Alter Macrophage Cytokine Signaling and Bacterial Heavy Metal Response

结核分枝杆菌中ESX-5基因缺失会改变巨噬细胞细胞因子信号传导和细菌对重金属的反应

Haynes, Austin M; Cohen, Sara B; Pesaladinne, Aparajita; Sherman, David R; Urdahl, Kevin B; Cox, Jeffery S; Hawn, Thomas R

TOLLIP inhibits lipid accumulation and the integrated stress response in alveolar macrophages to control Mycobacterium tuberculosis infection

TOLLIP抑制肺泡巨噬细胞中的脂质积累和整合应激反应,从而控制结核分枝杆菌感染。

Venkatasubramanian, Sambasivan; Plumlee, Courtney R; Dill-McFarland, Kimberly A; Cohen, Sara B; Gern, Benjamin H; Rane, Divya A; Meyer, Mackenzie K; Saha, Aparajita; Hinderstein, Sarah A; Pearson, Gemma L; Lietzke, Anne C; Pacheco, Amanda; Chow, Yu-Hua; Hung, Chi F; Soleimanpour, Scott A; Altman, Matthew; Urdahl, Kevin B; Shah, Javeed A

Weaponizing the bystander T cell army to fight tuberculosis

利用旁观者T细胞大军对抗结核病

Cohen, Sara B; Urdahl, Kevin B

Host and pathogen genetic diversity shape vaccine-mediated protection to Mycobacterium tuberculosis

宿主和病原体的遗传多样性影响疫苗介导的对结核分枝杆菌的保护作用

Cohen, Sara B; Plumlee, Courtney R; Engels, Lindsay; Mai, Dat; Murray, Tara A; Jahn, Ana N; Alexander, Bridget; Delahaye, Jared L; Cross, Lauren M; Maciag, Karolina; Schrader, Sam; Durga, Kaitlin; Gold, Elizabeth S; Aderem, Alan; Gerner, Michael Y; Gern, Benjamin H; Diercks, Alan H; Urdahl, Kevin B

Molecular detection of pre-ribosomal RNAs of Mycobacterium bovis bacille Calmette-Guérin and Mycobacterium tuberculosis to enhance pre-clinical tuberculosis drug and vaccine development

利用分子检测牛分枝杆菌卡介苗和结核分枝杆菌的前核糖体RNA,以促进结核病药物和疫苗的临床前研发。

Chang, Ming; Venkatasubramanian, Sambasivan; Barrett, Holly; Urdahl, Kevin B; Weigel, Kris M; Cangelosi, Gerard A; Shah, Javeed A; Saha, Aparajita; Feng, Libing; Adams, Kristin N; Sherman, David R; Smith, Nahum; Seshadri, Chetan; Kublin, James G; Murphy, Sean C

Assessing vaccine-mediated protection in an ultra-low dose Mycobacterium tuberculosis murine model

在超低剂量结核分枝杆菌小鼠模型中评估疫苗介导的保护作用

Plumlee, Courtney R; Barrett, Holly W; Shao, Danica E; Lien, Katie A; Cross, Lauren M; Cohen, Sara B; Edlefsen, Paul T; Urdahl, Kevin B

Cascade Immune Mechanisms of Protection against Mycobacterium tuberculosis (IMPAc-TB): study protocol for the Household Contact Study in the Western Cape, South Africa

抗结核分枝杆菌级联免疫保护机制(IMPAc-TB):南非西开普省家庭接触者研究方案

Hiemstra, Andriёtte M; MacDonald, Candice E; van Rensburg, Ilana C; Stanley, Kim; Maasdorp, Elizna; Mc Anda, Shirley; Tönsing, Susanne; Shaw, Jane Alexandra; Tromp, Gerard; van der Spuy, Gian D; Urdahl, Kevin B; Lewinsohn, David M; Kuivaniemi, Helena; Du Plessis, Nelita; Malherbe, Stephanus T; Walzl, Gerhard