日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

A genome-scale single-cell CRISPRi map of trans gene regulation across human pluripotent stem cell lines.

人类多能干细胞系中跨基因调控的基因组规模单细胞 CRISPRi 图谱。

期刊:Cell Genomics
影响因子:9
doi:10.1016/j.xgen.2025.101076
Feng Claudia, Peets Elin Madli, Zhou Yan, Crepaldi Luca, Usluer Sunay, Dunham Alistair, Braunger Jana M, Su Jing, Strauss Magdalena E, Muraro Daniele, Xian Cheam Kimberly Ai, Bonder Marc Jan, Nogales Edgar Garriga, Cooper Sarah, Bassett Andrew, Leonard Steven, Gu Yong, Fussing Bo, Burke David, Parts Leopold, Stegle Oliver, Velten Britta
发育与干细胞
信号转导
干细胞
细胞生物学
单细胞
发表日期：2026
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The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4-DRI.

无序的 p53 转录激活结构域是 FOXO4 和衰老细胞清除化合物 FOXO4-DRI 的靶点

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-60844-9
Bourgeois Benjamin, Spreitzer Emil, Platero-Rochart Daniel, Paar Margret, Zhou Qishun, Usluer Sinem, de Keizer Peter L J, Burgering Boudewijn M T, Sánchez-Murcia Pedro A, Madl Tobias
细胞生物学
P53
细胞衰老
发表日期：2025
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Insights into Natural History, Phenotypic, and Molecular Spectrum in a Large Cohort of Osteosclerotic Disorders

对大量骨硬化性疾病患者的自然史、表型和分子谱的深入了解

期刊:Calcified Tissue International
影响因子:3.2
doi:10.1007/s00223-025-01366-w
Uludağ Alkaya, Dilek; Usluer, Esra; Alp Ünkar, Zeynep; Şeker, Ali; Adaletli, İbrahim; Güneş, Nilay; Madazlı, Rıza; Kadıoğlu, Pınar; Derbent, Murat; Tüysüz, Beyhan
发表日期：2025
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Expanding the Clinical and Molecular Spectrum of Primary Autosomal Recessive Microcephaly: Novel CDK5RAP2 Gene Variants and Functional Insights on the Intronic Variants

拓展原发性常染色体隐性遗传小头畸形的临床和分子谱：新型 CDK5RAP2 基因变异及内含子变异的功能解析

期刊:Genes
影响因子:2.8
doi:10.3390/genes16101120
Yeter, Burcu; Kendir Demirkol, Yasemin; Usluer, Esra; Görüşen Kavak, İpek; Ergin, Sena Gjota; Elçioğlu, Nursel H
CDK5
发表日期：2025
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Optimized whole-genome CRISPR interference screens identify ARID1A-dependent growth regulators in human induced pluripotent stem cells

优化的全基因组 CRISPR 干扰筛选可识别人类诱导多能干细胞中 ARID1A 依赖的生长调节剂

期刊:Stem Cell Reports
影响因子:5.9
doi:10.1016/j.stemcr.2023.03.008
Sunay Usluer, Pille Hallast, Luca Crepaldi, Yan Zhou, Katie Urgo, Cansu Dincer, Jing Su, Guillaume Noell, Kaur Alasoo, Omar El Garwany, Sebastian S Gerety, Ben Newman, Oliver M Dovey, Leopold Parts
发育与干细胞
干细胞
发表日期：2023
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Fasting improves therapeutic response in hepatocellular carcinoma through p53-dependent metabolic synergism

禁食通过p53依赖性代谢协同作用改善肝细胞癌的治疗反应

期刊:Science Advances
影响因子:11.7
doi:10.1126/sciadv.abh2635
Jelena Krstic,Isabel Reinisch,Katharina Schindlmaier,Markus Galhuber,Zina Riahi,Natascha Berger,Nadja Kupper,Elisabeth Moyschewitz,Martina Auer,Helene Michenthaler,Christoph Nössing,Maria R Depaoli,Jeta Ramadani-Muja,Sinem Usluer,Sarah Stryeck,Martin Pichler,Beate Rinner,Alexander J A Deutsch,Andreas Reinisch,Tobias Madl,Riccardo Zenezini Chiozzi,Albert J R Heck,Meritxell Huch,Roland Malli,Andreas Prokesch
肝癌
细胞生物学
代谢
肿瘤
P53
发表日期：2022
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XIAP restrains TNF-driven intestinal inflammation and dysbiosis by promoting innate immune responses of Paneth and dendritic cells

XIAP 通过促进潘氏细胞和树突状细胞的先天免疫反应来抑制 TNF 驱动的肠道炎症和菌群失调

期刊:Science Immunology
影响因子:17.6
doi:10.1126/sciimmunol.abf7235
Adam Wahida, Madeleine Müller, Andreas Hiergeist, Bastian Popper, Katja Steiger, Caterina Branca, Markus Tschurtschenthaler, Thomas Engleitner, Sainitin Donakonda, Jordy De Coninck, Rupert Öllinger, Marie K Pfautsch, Nicole Müller, Miguel Silva, Sinem Usluer, Erik Thiele Orberg, Jan P Böttcher, Nico
信号转导
免疫
肠炎
树突状细胞
CII
发表日期：2021
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ATP regulates RNA-driven cold inducible RNA binding protein phase separation

ATP调控RNA驱动的冷诱导RNA结合蛋白相分离

期刊:Protein Science
影响因子:5.2
doi:10.1002/pro.4123
Zhou, Qishun; Usluer, Sinem; Zhang, Fangrong; Lenard, Aneta J; Bourgeois, Benjamin M R; Madl, Tobias
信号转导
相分离
发表日期：2021
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Phosphorylation Regulates CIRBP Arginine Methylation, Transportin-1 Binding and Liquid-Liquid Phase Separation

磷酸化调节 CIRBP 精氨酸甲基化、转运蛋白-1 结合和液-液相分离

期刊:Frontiers in Molecular Biosciences
影响因子:3.9
doi:10.3389/fmolb.2021.689687
Aneta J Lenard, Saskia Hutten, Qishun Zhou, Sinem Usluer, Fangrong Zhang, Benjamin M R Bourgeois, Dorothee Dormann, Tobias Madl
表观遗传
发表日期：2021
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Nuclear Import Receptors Directly Bind to Arginine-Rich Dipeptide Repeat Proteins and Suppress Their Pathological Interactions

核输入受体直接与富含精氨酸的二肽重复蛋白结合并抑制其病理性相互作用

期刊:Cell Reports
影响因子:7.5
doi:10.1016/j.celrep.2020.108538
Saskia Hutten ,Sinem Usluer ,Benjamin Bourgeois ,Francesca Simonetti ,Hana M Odeh ,Charlotte M Fare ,Mareike Czuppa ,Marian Hruska-Plochan ,Mario Hofweber ,Magdalini Polymenidou ,James Shorter ,Dieter Edbauer ,Tobias Madl ,Dorothee Dormann
信号转导
发表日期：2020
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