日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Targeted knock-in of NCF1 cDNA into the NCF2 locus leads to myeloid phenotypic correction of p47 phox -deficient chronic granulomatous disease

将 NCF1 cDNA 靶向敲入 NCF2 基因座可导致 p47 phox 缺陷型慢性肉芽肿病的髓系表型校正

Kah Mun Siow, Merve Güngör, Dominik Wrona, Federica Raimondi, Oleksandr Pastukhov, Panagiotis Tsapogas, Timon Menzi, Michael Schmitz, Péter István Kulcsár, Gerald Schwank, Ansgar Schulz, Martin Jinek, Ute Modlich, Ulrich Siler, Janine Reichenbach

Gene editing of NCF1 loci is associated with homologous recombination and chromosomal rearrangements

NCF1 基因位点的基因编辑与同源重组和染色体重排有关

Federica Raimondi, Kah Mun Siow, Dominik Wrona, Carla Fuster-García, Oleksandr Pastukhov, Michael Schmitz, Katja Bargsten, Lucas Kissling, Daan C Swarts, Geoffroy Andrieux, Toni Cathomen, Ute Modlich, Martin Jinek, Ulrich Siler #, Janine Reichenbach #

Lentiviral gene therapy reverts GPIX expression and phenotype in Bernard-Soulier syndrome type C

慢病毒基因治疗可逆转 Bernard-Soulier 综合征 C 型中的 GPIX 表达和表型

Gonzalo Martinez-Navajas, Jorge Ceron-Hernandez, Iris Simon, Pablo Lupiañez, Sofia Diaz-McLynn, Sonia Perales, Ute Modlich, Jose A Guerrero, Francisco Martin, Teresa Sevivas, Maria L Lozano, Jose Rivera, Veronica Ramos-Mejia, Claudia Tersteeg, Pedro J Real

Expression of a large coding sequence: Gene therapy vectors for Ataxia Telangiectasia

大编码序列的表达:毛细血管扩张性共济失调症的基因治疗载体

Tanja Hirch ,Nadine Brander ,Franziska Schenk ,Simon J Pöllmann ,Janine Reichenbach ,Ralf Schubert ,Ute Modlich

Influenza A virus infection instructs hematopoiesis to megakaryocyte-lineage output

型流感病毒感染指示造血向巨核细胞谱系输出

Marcel G E Rommel, Lisa Walz, Foteini Fotopoulou, Saskia Kohlscheen, Franziska Schenk, Csaba Miskey, Lacramioara Botezatu, Yvonne Krebs, Iris M Voelker, Kevin Wittwer, Tim Holland-Letz, Zoltán Ivics, Veronika von Messling, Marieke A G Essers, Michael D Milsom, Christian K Pfaller, Ute Modlich

Targeting transgenic proteins to alpha granules for platelet-directed gene therapy

将转基因蛋白靶向 α 颗粒用于血小板定向基因治疗

Vanessa M A Woods, Lisette J Latorre-Rey, Franziska Schenk, Marcel G E Rommel, Thomas Moritz, Ute Modlich

Predicting genotoxicity of viral vectors for stem cell gene therapy using gene expression-based machine learning

使用基于基因表达的机器学习预测干细胞基因治疗病毒载体的基因毒性

Adrian Schwarzer, Steven R Talbot, Anton Selich, Michael Morgan, Juliane W Schott, Oliver Dittrich-Breiholz, Antonella L Bastone, Bettina Weigel, Teng Cheong Ha, Violetta Dziadek, Rik Gijsbers, Adrian J Thrasher, Frank J T Staal, Hubert B Gaspar, Ute Modlich, Axel Schambach, Michael Rothe0

High Cytotoxic Efficiency of Lentivirally and Alpharetrovirally Engineered CD19-Specific Chimeric Antigen Receptor Natural Killer Cells Against Acute Lymphoblastic Leukemia

慢病毒和 α 逆转录病毒工程化的 CD19 特异性嵌合抗原受体自然杀伤细胞对急性淋巴细胞白血病具有高细胞毒效率

Stephan Müller, Tobias Bexte, Veronika Gebel, Franziska Kalensee, Eva Stolzenberg, Jessica Hartmann, Ulrike Koehl, Axel Schambach, Winfried S Wels, Ute Modlich, Evelyn Ullrich1

Zika virus infection studies with CD34+ hematopoietic and megakaryocyte-erythroid progenitors, red blood cells and platelets

使用 CD34+ 造血细胞和巨核细胞-红系祖细胞、红细胞和血小板进行寨卡病毒感染研究

Hanna Roth, Lucas Schneider, Regina Eberle, Jörn Lausen, Ute Modlich, Johannes Blümel, Sally A Baylis

Hematopoietic Stem Cell Transplantation Restores Naïve T-Cell Populations in Atm-Deficient Mice and in Preemptively Treated Patients With Ataxia-Telangiectasia

造血干细胞移植可恢复 Atm 缺乏小鼠和接受预先治疗的共济失调毛细血管扩张症患者的幼稚 T 细胞群

Ruth Duecker, Patrick C Baer, Aileen Buecker, Sabine Huenecke, Lisa-Marie Pfeffermann, Ute Modlich, Shahrzad Bakhtiar, Peter Bader, Stefan Zielen, Ralf Schubert