CCL2, but not its receptor, is essential to restrict immune privileged central nervous system-invasion of Japanese encephalitis virus via regulating accumulation of CD11b(+) Ly-6C(hi) monocytes
CCL2(而非其受体)对于限制日本脑炎病毒通过免疫豁免途径入侵中枢神经系统至关重要,其作用机制是通过调节 CD11b(+) Ly-6C(hi) 单核细胞的积累。
期刊:Immunology
影响因子:5
doi:10.1111/imm.12626
Kim, Jin Hyoung; Patil, Ajit Mahadev; Choi, Jin Young; Kim, Seong Bum; Uyangaa, Erdenebileg; Hossain, Ferdaus Mohd Altaf; Park, Sang-Youel; Lee, John Hwa; Kim, Koanhoi; Eo, Seong Kug
脑炎
CCL2
信号转导
神经科学
微生物学
单核细胞
细胞生物学
免疫/内分泌