日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Human iPSC-Derived Mononuclear Phagocytes Improve Cognition and Neural Health across Multiple Mouse Models of Aging and Alzheimer's Disease.

人类 iPSC 衍生的单核吞噬细胞可改善多种衰老和阿尔茨海默病小鼠模型的认知和神经健康。

Moser V Alexandra, Dimas-Harms Luz Jovita, Lipman Rachel M, Inzalaco Jake, Bell Shaughn, Alcantara Michelle, Valenzuela Erikha, Lawless George, Kreimer Simion, Parker Sarah J, Goodridge Helen S, Svendsen Clive N

Multi-lineage heart-chip models drug cardiotoxicity and enhances maturation of human stem cell-derived cardiovascular cells.

多谱系心脏芯片模拟药物心脏毒性,并促进人类干细胞衍生心血管细胞的成熟

Mozneb Maedeh, Jenkins Amelia, Sances Samuel, Pohlman Stephany, Workman Michael J, West Dylan, Ondatje Briana, El-Ghazawi Kareem, Woodbury Amanda, Garcia Veronica J, Patel Shachi, Arzt Madelyn, Dezem Felipe, Laperle Alex H, Moser V Alexandra, Ho Ritchie, Yucer Nur, Plummer Jasmine, Barrett Robert J, Svendsen Clive N, Sharma Arun

Human iPSC-derived neural progenitor cells secreting GDNF provide protection in rodent models of ALS and retinal degeneration

分泌GDNF的人类iPSC衍生神经祖细胞在ALS和视网膜变性啮齿动物模型中提供保护作用。

Laperle, Alexander H; Moser, V Alexandra; Avalos, Pablo; Lu, Bin; Wu, Amanda; Fulton, Aaron; Ramirez, Stephany; Garcia, Veronica J; Bell, Shaughn; Ho, Ritchie; Lawless, George; Roxas, Kristina; Shahin, Saba; Shelest, Oksana; Svendsen, Soshana; Wang, Shaomei; Svendsen, Clive N

Microglial transcription profiles in mouse and human are driven by APOE4 and sex

小鼠和人类的小胶质细胞转录谱由 APOE4 和性别驱动

V Alexandra Moser, Michael J Workman, Samantha J Hurwitz, Rachel M Lipman, Christian J Pike, Clive N Svendsen

Rejuvenating the blood and bone marrow to slow aging-associated cognitive decline and Alzheimer's disease

通过激活血液和骨髓来延缓与衰老相关的认知能力下降和阿尔茨海默病

Kang, Seokjo; Moser, V Alexandra; Svendsen, Clive N; Goodridge, Helen S

Young bone marrow transplantation preserves learning and memory in old mice

年轻骨髓移植可保留老年小鼠的学习能力和记忆力

Melanie M Das, Marlesa Godoy, Shuang Chen, V Alexandra Moser, Pablo Avalos, Kristina M Roxas, Ivy Dang, Alberto Yáñez, Wenxuan Zhang, Catherine Bresee, Moshe Arditi, George Y Liu, Clive N Svendsen, Helen S Goodridge

Effects of aging, high-fat diet, and testosterone treatment on neural and metabolic outcomes in male brown Norway rats

衰老、高脂饮食和睾酮治疗对雄性褐挪威大鼠神经和代谢结果的影响

Moser, V Alexandra; Christensen, Amy; Liu, Jiahui; Zhou, Amanda; Yagi, Shunya; Beam, Christopher R; Galea, Liisa; Pike, Christian J

TLR4 inhibitor TAK-242 attenuates the adverse neural effects of diet-induced obesity

TLR4 抑制剂 TAK-242 可减轻饮食引起的肥胖对神经的不良影响

V Alexandra Moser, Mariana F Uchoa, Christian J Pike

Obesity Accelerates Alzheimer-Related Pathology in APOE4 but not APOE3 Mice

肥胖会加速 APOE4 小鼠的阿尔茨海默病相关病理,但不会加速 APOE3 小鼠的阿尔茨海默病相关病理

V Alexandra Moser, Christian J Pike

Interactions between inflammation, sex steroids, and Alzheimer's disease risk factors

炎症、性激素和阿尔茨海默病风险因素之间的相互作用

Uchoa, Mariana F; Moser, V Alexandra; Pike, Christian J