Granzyme B triggers a prolonged pressure to die in Bcl-2 overexpressing cells, defining a window of opportunity for effective treatment with ABT-737
颗粒酶 B 可引发 Bcl-2 过表达细胞的长期死亡压力,为使用 ABT-737 进行有效治疗创造机会
期刊:Cell Death & Disease
影响因子:8.1
doi:10.1038/cddis.2012.73
V R Sutton, K Sedelies, G Dewson, M E Christensen, P I Bird, R W Johnstone, R M Kluck, J A Trapani, N J Waterhouse