Inclusion of a retroviral protease enhances the immunogenicity of VLP-forming mRNA vaccines against HIV-1 or SARS-CoV-2 in mice.
在小鼠体内加入逆转录病毒蛋白酶可增强形成病毒样颗粒的mRNA疫苗对HIV-1或SARS-CoV-2的免疫原性
期刊:Science Translational Medicine
影响因子:14.6
doi:10.1126/scitranslmed.adt9576
Zhang Peng, Singh Mamta, Becker Vada A, Croft Jacob, Tsybovsky Yaroslav, Gopan Vinay, Seo Yuna, Liu Qingbo, Rogers Denise, Miao Huiyi, Lin Yin, Rogan Daniel, Shields Courtney, Elbashir Sayda M, Calabrese Samantha, Renzi Isabella, Preznyak Vladimir, Narayanan Elizabeth, Stewart-Jones Guillaume, Himansu Sunny, Connors Mark, Lee Kelly, Carfi Andrea, Lusso Paolo
