日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

C5aR1 Inhibition Alleviates Cranial Radiation-Induced Cognitive Decline.

C5aR1抑制可缓解颅脑放射引起的认知能力下降。

Krattli Robert P Jr, Do An H, El-Khatib Sanad M, Alikhani Leila, Markarian Mineh, Vagadia Arya R, Usmani Manal T, Madan Shreya, Baulch Janet E, Clark Richard J, Woodruff Trent M, Tenner Andrea J, Acharya Munjal M

Discovery of Potent and Selective MNK Kinase Inhibitors for the Treatment of Leukemia

发现用于治疗白血病的高效选择性MNK激酶抑制剂

Vagadia, Purav P; Izquierdo-Ferrer, Javier; Mazewski, Candice; Blyth, Gavin; Beauchamp, Elspeth M; Clutter, Matthew R; Stern, Charlotte L; Mishra, Rama K; Nahotko, Dominik; Small, Sara; Eckerdt, Frank; Platanias, Leonidas C; Schiltz, Gary E

Correction: BDNF augmentation reverses cranial radiation therapy-induced cognitive decline and neurodegenerative consequences

更正:补充脑源性神经营养因子(BDNF)可逆转颅脑放射治疗引起的认知能力下降和神经退行性后果。

El-Khatib, Sanad M; Vagadia, Arya R; Le, Anh C D; Baulch, Janet E; Ng, Ding Quan; Du, Mingyu; Johnston, Kevin G; Tan, Zhiqun; Xu, Xiangmin; Chan, Alexandre; Acharya, Munjal M

Development of a SIN1 targeting inhibitor as a novel therapeutic approach for the treatment of malignancies

开发一种靶向SIN1的抑制剂作为治疗恶性肿瘤的新型治疗方法

Beauchamp, Elspeth M; Jain, Atul; Clutter, Matt; Nahotko, Dominik; Lopez Fajardo, Emely; Vagadia, Purav P; Dunne, Sara F; Mina, Alain; Fischietti, Mariafausta; Oku, Chidera V; Blyth, Gavin T; Mishra, Rama K; Karras, Elena; Radecki, Sara G; Lantz, Connor; Addepalli, Sidharth; Modi, Mirage; Zou, Lihua; Cho, Byoung-Kyu; Goo, Young Ah; Rossoff, Jenna; Fish, Eleanor N; Saleiro, Diana; Schiltz, Gary E; Platanias, Leonidas C

DART.2: bidirectional synaptic pharmacology with thousandfold cellular specificity.

DART.2:具有千倍细胞特异性的双向突触药理学

Shields Brenda C, Yan Haidun, Lim Shaun S X, Burwell Sasha C V, Cammarata Celine M, Fleming Elizabeth A, Yousefzadeh S Aryana, Goldenshtein Victoria Z, Kahuno Elizabeth W, Vagadia Purav P, Loughran Marie H, Zhiquan Lei, McDonnell Mark E, Scalabrino Miranda L, Thapa Mishek, Hawley Tammy M, Field Greg D, Hull Court, Schiltz Gary E, Glickfeld Lindsey L, Reitz Allen B, Tadross Michael R

BDNF augmentation reverses cranial radiation therapy-induced cognitive decline and neurodegenerative consequences

BDNF 增强可逆转颅脑放射治疗引起的认知能力下降和神经退行性后果

Sanad M El-Khatib, Arya R Vagadia, Anh C D Le, Janet E Baulch, Ding Quan Ng, Mingyu Du, Kevin G Johnston, Zhiqun Tan, Xiangmin Xu, Alexandre Chan, Munjal M Acharya

Discovery and Characterization of PROTACs Targeting Tissue Transglutaminase (TG2)

组织转谷氨酰胺酶 (TG2) 靶向 PROTAC 的发现与表征

Andres Valdivia ,Purav P Vagadia ,Guangxu Guo ,Eilidh O'Brien ,Daniela Matei ,Gary E Schiltz

Heterologous Expression of the Unusual Terreazepine Biosynthetic Gene Cluster Reveals a Promising Approach for Identifying New Chemical Scaffolds

不寻常的 Terreazepine 生物合成基因簇的异源表达揭示了一种识别新化学支架的有前途的方法

Lindsay K Caesar #, Matthew T Robey #, Michael Swyers, Md N Islam, Rosa Ye, Purav P Vagadia, Gary E Schiltz, Paul M Thomas, Chengcang C Wu, Neil L Kelleher, Nancy P Keller, Jin Woo Bok0

Synthesis and Biological Evaluation of 3-Arylindazoles as Selective MEK4 Inhibitors

3-芳基吲唑类化合物作为选择性MEK4抑制剂的合成及生物学评价

Deibler, Kristine K; Schiltz, Gary E; Clutter, Matthew R; Mishra, Rama K; Vagadia, Purav P; O'Connor, Matthew; George, Mariam Donny; Gordon, Ryan; Fowler, Graham; Bergan, Raymond; Scheidt, Karl A