日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Functional Cure for Hepatitis B Virus: Challenges and Achievements

乙型肝炎病毒的功能性治愈:挑战与成就

Shechter, Oren; Sausen, Daniel G; Dahari, Harel; Vaillant, Andrew; Cotler, Scott J; Borenstein, Ronen

HBV serum RNA kinetics during nucleic acid polymers based therapy predict functional cure

基于核酸聚合物的治疗过程中HBV血清RNA动力学可预测功能性治愈

Hershkovich, Leeor; Cotler, Scott J; Shekhtman, Louis; Bazinet, Michel; Anderson, Mark; Kuhns, Mary; Cloherty, Gavin; Vaillant, Andrew; Dahari, Harel

Rapid monophasic HBsAg decline during nucleic-acid polymer-based therapy predicts functional cure

核酸聚合物疗法期间HBsAg快速单相下降预示着功能性治愈

Hershkovich, Leeor; Shekhtman, Louis; Bazinet, Michel; Pântea, Victor; Placinta, Gheorge; Cotler, Scott J; Vaillant, Andrew; Dahari, Harel

Editorial: In vitro mechanistic evaluation of nucleic acid polymers: A cautionary tale

社论:核酸聚合物的体外机制评价:一个警示故事

Vaillant, Andrew

HBsAg isoform dynamics during NAP-based therapy of HBeAg-negative chronic HBV and HBV/HDV infection

在以NAP为基础的治疗方案中,HBeAg阴性慢性HBV和HBV/HDV感染期间HBsAg亚型的动态变化

Bazinet, Michel; Anderson, Mark; Pântea, Victor; Placinta, Gheorghe; Moscalu, Iurie; Cebotarescu, Valentin; Cojuhari, Lilia; Jimbei, Pavlina; Iarovoi, Liviu; Smesnoi, Valentina; Musteata, Tatina; Jucov, Alina; Dittmer, Ulf; Gersch, Jeff; Holzmayer, Vera; Kuhns, Mary; Cloherty, Gavin; Vaillant, Andrew

Oligonucleotide-Based Therapies for Chronic HBV Infection: A Primer on Biochemistry, Mechanisms and Antiviral Effects

寡核苷酸疗法治疗慢性乙型肝炎病毒感染:生物化学、机制和抗病毒作用简介

Vaillant, Andrew

Letter to the Editor: Examining HBV-RNA Kinetics During NA Treatment-Are NAs Multifunctional Antiviral Agents?

致编辑的信:在核苷(酸)类似物(NA)治疗期间检测 HBV-RNA 动力学——核苷(酸)类似物是多功能抗病毒药物吗?

Dahari, Harel; Vaillant, Andrew; Cotler, Scott J

Persistent Control of Hepatitis B Virus and Hepatitis Delta Virus Infection Following REP 2139-Ca and Pegylated Interferon Therapy in Chronic Hepatitis B Virus/Hepatitis Delta Virus Coinfection

在慢性乙型肝炎病毒/丁型肝炎病毒合并感染患者中,REP 2139-Ca 和聚乙二醇干扰素治疗可持续控制乙型肝炎病毒和丁型肝炎病毒感染。

Bazinet, Michel; Pântea, Victor; Cebotarescu, Valentin; Cojuhari, Lilia; Jimbei, Pavlina; Anderson, Mark; Gersch, Jeff; Holzmayer, Vera; Elsner, Carina; Krawczyk, Adalbert; Kuhns, Mary C; Cloherty, Gavin; Dittmer, Ulf; Vaillant, Andrew

Analysis of HBsAg Immunocomplexes and cccDNA Activity During and Persisting After NAP-Based Therapy

在基于NAP的治疗期间及治疗后持续存在的HBsAg免疫复合物和cccDNA活性的分析

Bazinet, Michel; Anderson, Mark; Pântea, Victor; Placinta, Gheorghe; Moscalu, Iurie; Cebotarescu, Valentin; Cojuhari, Lilia; Jimbei, Pavlina; Iarovoi, Liviu; Smesnoi, Valentina; Musteata, Tatina; Jucov, Alina; Dittmer, Ulf; Gersch, Jeff; Holzmayer, Vera; Kuhns, Mary; Cloherty, Gavin; Vaillant, Andrew

Modelling hepatitis D virus RNA and HBsAg dynamics during nucleic acid polymer monotherapy suggest rapid turnover of HBsAg

在核酸聚合物单药治疗期间,对丁型肝炎病毒RNA和HBsAg动态变化的建模表明,HBsAg周转迅速。

Shekhtman, Louis; Cotler, Scott J; Hershkovich, Leeor; Uprichard, Susan L; Bazinet, Michel; Pantea, Victor; Cebotarescu, Valentin; Cojuhari, Lilia; Jimbei, Pavlina; Krawczyk, Adalbert; Dittmer, Ulf; Vaillant, Andrew; Dahari, Harel