日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Optimal Dosage Justification for Datopotamab Deruxtecan in HR-Positive/HER2-Negative Breast Cancer Through Model-Informed Drug Development Approaches

通过模型指导的药物开发方法，确定达托泊单抗德鲁西替康在HR阳性/HER2阴性乳腺癌中的最佳剂量

期刊:Cts-Clinical and Translational Science
影响因子:2.8
doi:10.1111/cts.70493
Tang, Zoey; Lim, KyoungSoo; Jiang, Yu; Dai, David; Munegowda, Manjunatha; Khan, Sabrina; Xu, Lu; Shi, Lei; Pan, Yuzhuo; Hong, Ying; Ren, Song; Vajjah, Pavan; Gibbs, Megan; Zhou, Diansong
HER2
肿瘤
肿瘤免疫
乳腺癌
发表日期：2026
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Exposure-Response Analyses of Datopotamab Deruxtecan (Dato-DXd) in Patients with Hormone Receptor (HR) Positive, Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Breast Cancer

达托泊单抗德鲁替康（Dato-DXd）在激素受体（HR）阳性、人表皮生长因子受体2（HER2）阴性乳腺癌患者中的暴露-反应分析

期刊:Journal of Clinical Pharmacology
影响因子:2.3
doi:10.1002/jcph.70188
Tang, Zoey; Lim, KyoungSoo; Jiang, Yu; Denduluri, Neelima; Rokutanda, Nana; Pan, Yuzhuo; Hong, Ying; Ren, Song; Vajjah, Pavan; Zhou, Diansong
肿瘤
HER2
肿瘤免疫
信号转导
乳腺癌
Human
免疫/内分泌
发表日期：2026
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Strategies for clinical dose optimization of T cell-engaging therapies in oncology

肿瘤学中T细胞激活疗法的临床剂量优化策略

期刊:MAbs
影响因子:7.3
doi:10.1080/19420862.2023.2181016
Ball, Kathryn; Dovedi, Simon J; Vajjah, Pavan; Phipps, Alex
肿瘤
T细胞
肿瘤免疫
T细胞
细胞生物学
免疫/内分泌
发表日期：2023
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Bimekizumab for the treatment of moderate-to-severe plaque psoriasis: efficacy, safety, pharmacokinetics, pharmacodynamics and transcriptomics from a phase IIa, randomized, double-blind multicentre study

Bimekizumab治疗中重度斑块状银屑病：一项IIa期随机、双盲、多中心研究的疗效、安全性、药代动力学、药效学和转录组学分析

期刊:British Journal of Dermatology
影响因子:9.6
doi:10.1111/bjd.20827
Oliver, R; Krueger, J G; Glatt, S; Vajjah, P; Mistry, C; Page, M; Edwards, H; Garcet, S; Li, X; Dizier, B; Maroof, A; Watling, M; El Baghdady, A; Baeten, D; Ionescu, L; Shaw, S
银屑病
发表日期：2022
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Bimekizumab, a Novel Humanized IgG1 Antibody That Neutralizes Both IL-17A and IL-17F

Bimekizumab，一种可中和 IL-17A 和 IL-17F 的新型人源化 IgG1 抗体

期刊:Frontiers in Immunology
影响因子:5.7
doi:10.3389/fimmu.2020.01894
Ralph Adams, Asher Maroof, Terry Baker, Alastair D G Lawson, Ruth Oliver, Ross Paveley, Steve Rapecki, Stevan Shaw, Pavan Vajjah, Shauna West, Meryn Griffiths
IL-17
IL-17A
Human
IL-17F
IgG
发表日期：2020
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Dual IL-17A and IL-17F neutralisation by bimekizumab in psoriatic arthritis: evidence from preclinical experiments and a randomised placebo-controlled clinical trial that IL-17F contributes to human chronic tissue inflammation

bimekizumab 在银屑病关节炎中对 IL-17A 和 IL-17F 的双重中和作用：临床前实验和随机安慰剂对照临床试验的证据表明 IL-17F 会导致人类慢性组织炎症

期刊:Annals of the Rheumatic Diseases
影响因子:20.3
doi:10.1136/annrheumdis-2017-212127
Sophie Glatt, Dominique Baeten, Terry Baker, Meryn Griffiths, Lucian Ionescu, Alastair D G Lawson, Ash Maroof, Ruth Oliver, Serghei Popa, Foteini Strimenopoulou, Pavan Vajjah, Mark I L Watling, Nataliya Yeremenko, Pierre Miossec, Stevan Shaw
免疫
关节炎
银屑病
Human
发表日期：2018
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Randomized study of the safety and pharmacodynamics of inhaled interleukin-13 monoclonal antibody fragment VR942

吸入白细胞介素-13单克隆抗体片段VR942的安全性和药效学随机研究

期刊:EBioMedicine
影响因子:10.8
doi:10.1016/j.ebiom.2018.07.035
Burgess, Gary; Boyce, Malcolm; Jones, Margaret; Larsson, Lars; Main, Mark J; Morgan, Frazer; Phillips, Peter; Scrimgeour, Alison; Strimenopoulou, Foteini; Vajjah, Pavan; Zamacona, Miren; Palframan, Roger
单克隆抗体
细胞生物学
发表日期：2018
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Does age affect gastric emptying time? A model-based meta-analysis of data from premature neonates through to adults

年龄是否影响胃排空时间？一项基于模型的荟萃分析，纳入了从早产新生儿到成人的数据。

期刊:Biopharmaceutics & Drug Disposition
影响因子:2
doi:10.1002/bdd.1937
Bonner, Jennifer J; Vajjah, Pavan; Abduljalil, Khaled; Jamei, Masoud; Rostami-Hodjegan, Amin; Tucker, Geoffrey T; Johnson, Trevor N
发表日期：2015
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