Vakulenko Sergei B相关文献与解析，生知库

Attana, Fedaa; Kim, Soobin; Spencer, James; Iorga, Bogdan I; Docquier, Jean-Denis; Rossolini, Gian Maria; Perilli, Mariagrazia; Amicosante, Gianfranco; Vila, Alejandro J; Vakulenko, Sergei B; Mobashery, Shahriar; Bradford, Patricia; Bush, Karen; Partridge, Sally R; Hujer, Andrea M; Hujer, Kristine M; Bonomo, Robert A; Haider, Shozeb

发表日期：2025

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Dual mechanism of the OXA-23 carbapenemase inhibition by the carbapenem NA-1-157

碳青霉烯类抗生素NA-1-157对OXA-23碳青霉烯酶的双重抑制机制

期刊:Antimicrobial Agents and Chemotherapy

影响因子:4.5

doi:10.1128/aac.00918-25

Toth, Marta; Stewart, Nichole K; Quan, Pojun; Khan, Md Mahbub Kabir; Cox, Jonathan; Buynak, John D; Smith, Clyde A; Vakulenko, Sergei B

发表日期：2025

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Restricted Rotational Flexibility of the C5α-Methyl-Substituted Carbapenem NA-1-157 Leads to Potent Inhibition of the GES-5 Carbapenemase

C5α-甲基取代的碳青霉烯类抗生素NA-1-157的旋转灵活性受限，导致其对GES-5碳青霉烯酶具有强效抑制作用。

期刊:ACS Infectious Diseases

影响因子:3.8

doi:10.1021/acsinfecdis.3c00683

Stewart, Nichole K; Toth, Marta; Quan, Pojun; Beer, Michael; Buynak, John D; Smith, Clyde A; Vakulenko, Sergei B

发表日期：2024

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Decarboxylation of the Catalytic Lysine Residue by the C5α-Methyl-Substituted Carbapenem NA-1-157 Leads to Potent Inhibition of the OXA-58 Carbapenemase

C5α-甲基取代的碳青霉烯类抗生素NA-1-157通过催化赖氨酸残基的脱羧作用，有效抑制OXA-58碳青霉烯酶的活性。

期刊:ACS Infectious Diseases

影响因子:3.8

doi:10.1021/acsinfecdis.4c00671

Toth, Marta; Stewart, Nichole K; Maggiolo, Ailiena O; Quan, Pojun; Khan, Md Mahbub Kabir; Buynak, John D; Smith, Clyde A; Vakulenko, Sergei B

发表日期：2024

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The C5α-Methyl-Substituted Carbapenem NA-1-157 Exhibits Potent Activity against Klebsiella spp. Isolates Producing OXA-48-Type Carbapenemases

C5α-甲基取代的碳青霉烯类抗生素NA-1-157对产生OXA-48型碳青霉烯酶的克雷伯氏菌属分离株表现出强效活性。

期刊:ACS Infectious Diseases

影响因子:3.8

doi:10.1021/acsinfecdis.3c00059

Smith, Clyde A; Stewart, Nichole K; Toth, Marta; Quan, Pojun; Buynak, John D; Vakulenko, Sergei B

发表日期：2023

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C6 Hydroxymethyl-Substituted Carbapenem MA-1-206 Inhibits the Major Acinetobacter baumannii Carbapenemase OXA-23 by Impeding Deacylation

C6羟甲基取代的碳青霉烯类抗生素MA-1-206通过抑制脱酰基作用来抑制鲍曼不动杆菌的主要碳青霉烯酶OXA-23。

期刊:mBio

影响因子:4.7

doi:10.1128/mbio.00367-22

Stewart, Nichole K; Toth, Marta; Alqurafi, Maha A; Chai, Weirui; Nguyen, Thu Q; Quan, Pojun; Lee, Mijoon; Buynak, John D; Smith, Clyde A; Vakulenko, Sergei B

发表日期：2022

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Effects of Inactivation of d,d-Transpeptidases of Acinetobacter baumannii on Bacterial Growth and Susceptibility to β-Lactam Antibiotics

鲍曼不动杆菌D,D-转肽酶失活对细菌生长和β-内酰胺类抗生素敏感性的影响

期刊:Antimicrobial Agents and Chemotherapy

影响因子:4.5

doi:10.1128/AAC.01729-21

Toth, Marta; Lee, Mijoon; Stewart, Nichole K; Vakulenko, Sergei B

微生物学

发表日期：2022

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Inhibition of the Clostridioides difficile Class D β-Lactamase CDD-1 by Avibactam

阿维巴坦对艰难梭菌D类β-内酰胺酶CDD-1的抑制作用

期刊:ACS Infectious Diseases

影响因子:3.8

doi:10.1021/acsinfecdis.0c00714

Stewart, Nichole K; Toth, Marta; Stasyuk, Anastasiya; Lee, Mijoon; Smith, Clyde A; Vakulenko, Sergei B

CDD

发表日期：2021

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A surface loop modulates activity of the Bacillus class D β-lactamases

表面环调节芽孢杆菌D类β-内酰胺酶的活性

期刊:Journal of Structural Biology

影响因子:2.7

doi:10.1016/j.jsb.2020.107544

Stewart, Nichole K; Bhattacharya, Monolekha; Toth, Marta; Smith, Clyde A; Vakulenko, Sergei B

发表日期：2020

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Evolution of carbapenemase activity in the class C β-lactamase ADC-1

C类β-内酰胺酶ADC-1中碳青霉烯酶活性的演变

SAND: a comprehensive annotation of class D β-lactamases using structural alignment-based numbering

SAND：基于结构比对编号的D类β-内酰胺酶的综合注释

Dual mechanism of the OXA-23 carbapenemase inhibition by the carbapenem NA-1-157

碳青霉烯类抗生素NA-1-157对OXA-23碳青霉烯酶的双重抑制机制

Restricted Rotational Flexibility of the C5α-Methyl-Substituted Carbapenem NA-1-157 Leads to Potent Inhibition of the GES-5 Carbapenemase

C5α-甲基取代的碳青霉烯类抗生素NA-1-157的旋转灵活性受限，导致其对GES-5碳青霉烯酶具有强效抑制作用。

Decarboxylation of the Catalytic Lysine Residue by the C5α-Methyl-Substituted Carbapenem NA-1-157 Leads to Potent Inhibition of the OXA-58 Carbapenemase

C5α-甲基取代的碳青霉烯类抗生素NA-1-157通过催化赖氨酸残基的脱羧作用，有效抑制OXA-58碳青霉烯酶的活性。

The C5α-Methyl-Substituted Carbapenem NA-1-157 Exhibits Potent Activity against Klebsiella spp. Isolates Producing OXA-48-Type Carbapenemases

C5α-甲基取代的碳青霉烯类抗生素NA-1-157对产生OXA-48型碳青霉烯酶的克雷伯氏菌属分离株表现出强效活性。

C6 Hydroxymethyl-Substituted Carbapenem MA-1-206 Inhibits the Major Acinetobacter baumannii Carbapenemase OXA-23 by Impeding Deacylation

C6羟甲基取代的碳青霉烯类抗生素MA-1-206通过抑制脱酰基作用来抑制鲍曼不动杆菌的主要碳青霉烯酶OXA-23。

Effects of Inactivation of d,d-Transpeptidases of Acinetobacter baumannii on Bacterial Growth and Susceptibility to β-Lactam Antibiotics

鲍曼不动杆菌D,D-转肽酶失活对细菌生长和β-内酰胺类抗生素敏感性的影响

Inhibition of the Clostridioides difficile Class D β-Lactamase CDD-1 by Avibactam

阿维巴坦对艰难梭菌D类β-内酰胺酶CDD-1的抑制作用

A surface loop modulates activity of the Bacillus class D β-lactamases

表面环调节芽孢杆菌D类β-内酰胺酶的活性