日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

First-in-class SAM-competitive G9a inhibitor FLAV-27 as a disease-modifying therapy for Alzheimer disease.

首个SAM竞争性G9a抑制剂FLAV-27作为阿尔茨海默病疾病修饰疗法。

期刊:Molecular Therapy
影响因子:12
doi:10.1016/j.ymthe.2025.12.038
Bellver-Sanchis Aina, Valle-Garcia David, Barbaraci Carla, Romero-Becerra Fernando, Singh Rohit Kumar, Jarne-Ferrer Júlia, Vasilopoulou Foteini, Irisarri Alba, Martínez-Fernández Carmen, Fafián-Labora Juan A, Arufe María C, Wüst Carolin, Castellanos Aida, Soto David, Casals Núria, Fadó Rut, Pocock Jennifer M, Navarro Gemma, Val Cristina, Brea José, Loza M Isabel, Lleó Albert, Fortea Juan, Alcolea Daniel, Perez-Bosque Anna, Miró Lluïsa, Pérez Belén, Rashid Sajid, Ali Muhammad, Saqib Manahil, Lí Carbó Marcel, Guerrero Ana, Vázquez Santiago, Choudhary Bhanwar Singh, Dai Shaodong, Escolano Carmen, Franco Rafael, Pallàs Mercè, Griñán-Ferré Christian
阿尔茨海默症
神经科学
发表日期：2026
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A brain-penetrant P2X7R antagonist mitigates Alzheimer's disease pathology

一种能穿透血脑屏障的P2X7R拮抗剂可减轻阿尔茨海默病病理。

期刊:
影响因子:
doi:10.64898/2026.04.06.716621
Turcu, Andreea L; Oken, Adam C; Griñán-Ferré, Christian; Durner, Anna; Sierra-Marquez, Juan; Hinz-Kowalik, Sonja; Nagel, Jessica; Lee, So-Deok; Tzortzini, Efpraxia; Georgiou, Kyriakos; Bhol, Mamina; Baz, Zuriñe; Llop, Jordi; Schneider, Marion; Barbaraci, Carla; Kim, Ga-Ram; Barniol-Xicota, Marta; Val, Cristina; Brea, José; Loza, M Isabel; Pérez, Belén; Naesens, Lieve; Kolocouris, Antonios; Kim, Yong-Chul; Müller, Christa E; Nicke, Annette; Pallàs, Mercè; Mansoor, Steven E; Vázquez, Santiago
血脑屏障
阿尔茨海默症
神经科学
发表日期：2026
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Conformational Restriction of Designer Drugs Reveals Subtype-Selective and Biased CB(2) Agonists with Neuroprotective Effects.

构象限制设计药物揭示了具有神经保护作用的亚型选择性和偏向性 CB(2) 激动剂

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c00604
Gioé-Gallo Claudia, Ortigueira Sandra, Prieto-Díaz Rubén, Contino Marialessandra, Azuaje Jhonny, Perrone Maria Grazia, Riganti Chiara, Alberga Domenico, Mangiatordi Giuseppe Felice, Andújar-Arias Antonio, García-Rey Aitor, Graziano Giovanni, Stefanachi Angela, Val Cristina, Martínez Antón Leandro, Rebassa Joan Biel, Reza David, Selas Asier, Francavilla Fabio, Paleo M Rita, García-Mera Xerardo, Loza M Isabel, Navarro Gemma, Brea José, Sotelo Eddy
神经科学
药物研究
发表日期：2025
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Dimethoxybenzohomoadamantane-based soluble epoxide hydrolase inhibitors: in vivo efficacy in a murine model of chemotherapy-induced neuropathic pain

基于二甲氧基苯并高金刚烷的可溶性环氧化物水解酶抑制剂：在化疗诱导神经性疼痛小鼠模型中的体内疗效

期刊:Journal of Enzyme Inhibition and Medicinal Chemistry
影响因子:5.4
doi:10.1080/14756366.2025.2574990
Codony, Sandra; Jora, Beatrice; Santos-Caballero, Miriam; Qiu, Qiongju; Calvó-Tusell, Carla; Escriche, Celia; Turcu, Andreea L; Prischi, Filippo; Bartra, Clara; Val, Cristina; Morisseau, Christophe; Pérez, Belén; Bertran-Mostazo, Andrea; Osuna, Sílvia; Corpas, Rubén; Griñán-Ferré, Christian; Galdeano, Carles; Loza, M Isabel; Pallàs, Mercè; Sanfeliu, Coral; Hammock, Bruce D; Brea, José; Feixas, Ferran; Conte, Maria R; Cobos, Enrique J; Vázquez, Santiago
发表日期：2025
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Incidence of encephalopathy and comorbidity in infants with perinatal asphyxia: a comparative prospective cohort study

围产期窒息婴儿脑病及合并症的发生率：一项前瞻性队列研究

期刊:Frontiers in Pediatrics
影响因子:2
doi:10.3389/fped.2024.1363576
Vega-Del-Val, Cristina; Arnaez, Juan; Ochoa-Sangrador, Carlos; Garrido-Barbero, María; García-Alix, Alfredo
神经科学
发表日期：2024
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Computer-aided design of multi-target ligands at A(1)R, A(2A)R and PDE10A, key proteins in neurodegenerative diseases

利用计算机辅助设计针对神经退行性疾病关键蛋白 A(1)R、A(2A)R 和 PDE10A 的多靶点配体

期刊:Journal of Cheminformatics
影响因子:5.7
doi:10.1186/s13321-017-0249-4
Kalash, Leen; Val, Cristina; Azuaje, Jhonny; Loza, María I; Svensson, Fredrik; Zoufir, Azedine; Mervin, Lewis; Ladds, Graham; Brea, José; Glen, Robert; Sotelo, Eddy; Bender, Andreas
神经科学
PDE10
发表日期：2017
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