日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Signal Peptide Engineering and Codon Optimization to Enhance α-Gal A Activity for rAAV Gene Therapy of Fabry Disease

信号肽工程和密码子优化增强α-半乳糖苷酶A活性,用于法布里病的rAAV基因治疗

He, Siwu; Yang, Li; Wan, Ke; Zheng, Zhaoyue; Leng, Mi; Gan, Chunmei; Liu, Yu; Xiao, Lin; Ye, Jingya; Chen, Zhian; Zhou, Jiao; Valencia, C Alexander; Abuammah, Aliah; Chow, Hoi Yee; Dong, Biao; Chen, Yucheng

Production of SARS-CoV-2 virus-like particles as a vaccine candidate in stable cell lines through inducible E and M protein expression.

在稳定细胞系中通过诱导 E 和 M 蛋白表达生产 SARS-CoV-2 病毒样颗粒作为候选疫苗

Liu Yu, Chen Zhian, Yang Li, Gan Chunmei, Tang Jieshi, Zheng Zhaoyue, Ye JingYa, Valencia C Alexander, Chow Hoi Yee, Dong Biao

Deleterious variants in TNFAIP3 are associated with type II and seronegative pediatric autoimmune hepatitis

TNFAIP3基因的有害变异与II型和血清阴性儿童自身免疫性肝炎相关

Pandurangi, Sindhu; Malik, Astha; Owens, Joshua; Valencia, C Alexander; Miethke, Alexander G

DNA-encoded probe-based assay for profiling plant kinase activities

基于DNA编码探针的植物激酶活性分析方法

Chien, Yuan-Chi; Valencia, C Alexander; Lee, Han Yong; Yoon, Gyeong Mee; Kim, Dongwook

Clinical spectrum and genetic causes of mitochondrial hepatopathy phenotype in children

儿童线粒体肝病表型的临床表现谱和遗传病因

Squires, James E; Miethke, Alexander G; Valencia, C Alexander; Hawthorne, Kieran; Henn, Lisa; Van Hove, Johan L K; Squires, Robert H; Bove, Kevin; Horslen, Simon; Kohli, Rohit; Molleston, Jean P; Romero, Rene; Alonso, Estella M; Bezerra, Jorge A; Guthery, Stephen L; Hsu, Evelyn; Karpen, Saul J; Loomes, Kathleen M; Ng, Vicky L; Rosenthal, Philip; Mysore, Krupa; Wang, Kasper S; Friederich, Marisa W; Magee, John C; Sokol, Ronald J

Optimization of miR-22 expression cassette for rAAV delivery on diabetes

优化用于糖尿病rAAV递送的miR-22表达盒

Yang, Li; Du, Wenya; Zheng, Zhaoyue; Wang, Li; Xiao, Lin; Yang, Qingzhe; Hao, Qiukui; Zhou, Jiao; Du, Jintao; Li, Jun; Valencia, C Alexander; Dong, Birong; Chow, Hoi Yee; Fu, Xianghui; Dong, Biao

A vaccine based on the yeast-expressed receptor-binding domain (RBD) elicits broad immune responses against SARS-CoV-2 variants.

基于酵母表达的受体结合域 (RBD) 的疫苗可引发针对 SARS-CoV-2 变种的广泛免疫反应

Liu Yu, Zhao Danhua, Wang Yichang, Chen Zhian, Yang Li, Li Wenjuan, Gong Yanqiu, Gan Chunmei, Tang Jieshi, Zhang Tizhong, Tang Dan, Dong Xiuju, Yang Qingzhe, Valencia C Alexander, Dai Lunzhi, Qi Shiqian, Dong Biao, Chow Hoi Yee, Li Yuhua

Factor IX alteration p.Arg338Gln (FIX Shanghai) potentiates FIX clotting activity and causes thrombosis

因子IX变异p.Arg338Gln(上海型因子IX)增强因子IX的凝血活性并导致血栓形成

Wu, Wenman; Xiao, Lin; Wu, Xi; Xie, Xiaoling; Li, Ping; Chen, Changming; Zheng, Zhaoyue; Ai, Jiangang; Valencia, C Alexander; Dong, Birong; Ding, Qiulan; Dong, Biao; Wang, Xuefeng

An international telemedicine program for diagnosis of genetic disorders: Partnership of pediatrician and geneticist

一项用于诊断遗传疾病的国际远程医疗项目:儿科医生和遗传学家的合作

Mena, Rafael; Mendoza, Esperanza; Gomez Peña, Maria; Valencia, C Alexander; Ullah, Ehsan; Hufnagel, Robert B; Prada, Carlos E

Genetic and Transcriptomic Variation Linked to Neutrophil Granulocyte-Macrophage Colony-Stimulating Factor Signaling in Pediatric Crohn's Disease

儿童克罗恩病中与中性粒细胞-巨噬细胞集落刺激因子信号传导相关的遗传和转录组变异

Denson, Lee A; Jurickova, Ingrid; Karns, Rebekah; Shaw, Kelly A; Cutler, David J; Okou, David; Valencia, C Alexander; Dodd, Anne; Mondal, Kajari; Aronow, Bruce J; Haberman, Yael; Linn, Aaron; Price, Adam; Bezold, Ramona; Lake, Kathleen; Jackson, Kimberly; Walters, Thomas D; Griffiths, Anne; Baldassano, Robert N; Noe, Joshua D; Hyams, Jeffrey S; Crandall, Wallace V; Kirschner, Barbara S; Heyman, Melvin B; Snapper, Scott; Guthery, Stephen L; Dubinsky, Marla C; Leleiko, Neal S; Otley, Anthony R; Xavier, Ramnik J; Stevens, Christine; Daly, Mark J; Zwick, Michael E; Kugathasan, Subra