日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Identification of polychlorinated biphenyls (PCBs) and PCB metabolites associated with changes in the gut microbiome of female mice exposed to an environmental PCB mixture

鉴定与暴露于环境多氯联苯混合物的雌性小鼠肠道微生物群变化相关的多氯联苯（PCBs）及其代谢物

期刊:Journal of Hazardous materials
影响因子:11.3
doi:10.1016/j.jhazmat.2025.137688
Dean, Laura E; Wang, Hui; Li, Xueshu; Fitzjerrells, Rachel L; Valenzuela, Anthony E; Neier, Kari; LaSalle, Janine M; Mangalam, Ashutosh; Lein, Pamela J; Lehmler, Hans-Joachim
微生物学
代谢
发表日期：2025
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Air pollution and Alzheimer disease phenotype deplete esterified proresolving lipid mediator reserves in the brain.

空气污染和阿尔茨海默病表型会消耗大脑中酯化的促消解脂质介质储备

期刊:JCI Insight
影响因子:6.1
doi:10.1172/jci.insight.175917
Taha Ameer Y, Shen Qing, Otoki Yurika, Liang Nuanyi, Patten Kelley T, Valenzuela Anthony E, Wallis Christopher D, Rowland Douglas J, Chaudhari Abhijit J, Bein Keith J, Wexler Anthony S, Jin Lee-Way, Dugger Brittany N, Harvey Danielle J, Lein Pamela J
神经科学
发表日期：2025
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Bile Acid Profile Differs Between Brain Regions in Rodents and Is Disrupted in a Rodent Model of Alzheimer's Disease

啮齿动物大脑不同区域的胆汁酸谱存在差异，并且在阿尔茨海默病啮齿动物模型中发生紊乱

期刊:Comprehensive Physiology
影响因子:5.2
doi:10.1002/cph4.70034
Reuter, Melanie A; Moreno, Rosalinda; Agabao-Tucker, Madelynn E; Shishani, Rahaf; Bustamante, Jessica Miranda; Marfori, Zara; Richieri, Taylor; Valenzuela, Anthony E; Taha, Ameer Y; Lein, Pamela J; Nandakumar, Renu; Cummings, Bethany P
阿尔茨海默症
神经科学
发表日期：2025
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Spatial and spectral mapping of traffic-related air pollution (TRAP) nanoparticles in relation to plaques and inflammatory markers in an Alzheimer disease model

在阿尔茨海默病模型中，交通相关空气污染（TRAP）纳米颗粒与斑块和炎症标志物的空间和光谱映射关系研究

期刊:
影响因子:
doi:10.1101/2025.07.01.662638
O'Toole, Hannah J; James, Anchaleena; Nasim, Nathifa; Hadley, Dustin J; Hale, Elizabeth J; He, Qing; Bein, Keith J; Valenzuela, Anthony E; Rojalin, Tatu; Dugger, Brittany N; Wexler, Anthony S; Lein, Pamela J; Carney, Randy P
阿尔茨海默症
炎症/感染
炎症
发表日期：2025
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Interactions of Polychlorinated Biphenyls and Their Metabolites with the Brain and Liver Transcriptome of Female Mice

多氯联苯及其代谢物与雌性小鼠脑和肝脏转录组的相互作用

期刊:ACS Chemical Neuroscience
影响因子:3.9
doi:10.1021/acschemneuro.4c00367
Bullert, Amanda J; Wang, Hui; Valenzuela, Anthony E; Neier, Kari; Wilson, Rebecca J; Badley, Jessie R; LaSalle, Janine M; Hu, Xin; Lein, Pamela J; Lehmler, Hans-Joachim
神经科学
代谢
发表日期：2024
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Placental-brain axis in females detected within broadly impacted metabolic gene networks protects against prenatal PCB exposure

在广泛受影响的代谢基因网络中检测到的雌性胎盘-脑轴可保护胎儿免受产前多氯联苯暴露的影响

期刊:
影响因子:
doi:10.1101/2024.07.14.603326
Chau, Kelly; Neier, Kari; Valenzuela, Anthony E; Schmidt, Rebecca J; Durbin-Johnson, Blythe; Lein, Pamela J; Korf, Ian; LaSalle, Janine M
神经科学
代谢
发表日期：2024
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Chronic exposure to traffic-related air pollution reduces lipid mediators of linoleic acid and soluble epoxide hydrolase in serum of female rats.

长期暴露于交通相关空气污染会降低雌性大鼠血清中亚油酸和可溶性环氧化物水解酶的脂质介质

期刊:Environmental Toxicology and Pharmacology
影响因子:4.2
doi:10.1016/j.etap.2022.103875
Liang Nuanyi, Emami Shiva, Patten Kelley T, Valenzuela Anthony E, Wallis Christopher D, Wexler Anthony S, Bein Keith J, Lein Pamela J, Taha Ameer Y
免疫/内分泌
发表日期：2022
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Hippocampal but Not Serum Cytokine Levels Are Altered by Traffic-Related Air Pollution in TgF344-AD and Wildtype Fischer 344 Rats in a Sex- and Age-Dependent Manner

交通相关空气污染会以性别和年龄依赖的方式改变TgF344-AD和野生型Fischer 344大鼠海马体而非血清细胞因子水平。

期刊:Frontiers in Cellular Neuroscience
影响因子:4
doi:10.3389/fncel.2022.861733
Patten, Kelley T; Valenzuela, Anthony E; Wallis, Christopher; Harvey, Danielle J; Bein, Keith J; Wexler, Anthony S; Gorin, Fredric A; Lein, Pamela J
细胞生物学
Rat
Hippo
免疫/内分泌
发表日期：2022
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Chronic exposure to ambient traffic-related air pollution (TRAP) alters gut microbial abundance and bile acid metabolism in a transgenic rat model of Alzheimer's disease

长期暴露于交通相关空气污染（TRAP）会改变阿尔茨海默病转基因大鼠模型的肠道微生物丰度和胆汁酸代谢。

期刊:Toxicology Reports
影响因子:
doi:10.1016/j.toxrep.2022.03.003
Dutta, Moumita; Weigel, Kris M; Patten, Kelley T; Valenzuela, Anthony E; Wallis, Christopher; Bein, Keith J; Wexler, Anthony S; Lein, Pamela J; Cui, Julia Yue
微生物学
阿尔茨海默症
Rat
代谢
发表日期：2022
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Developmental Exposure to a Human-Relevant Polychlorinated Biphenyl Mixture Causes Behavioral Phenotypes That Vary by Sex and Genotype in Juvenile Mice Expressing Human Mutations That Modulate Neuronal Calcium

发育期暴露于与人类相关的多氯联苯混合物会导致表达调节神经元钙的人类突变的幼鼠出现因性别和基因型而异的行为表型。

期刊:Frontiers in Neuroscience
影响因子:3.2
doi:10.3389/fnins.2021.766826
Sethi, Sunjay; Keil Stietz, Kimberly P; Valenzuela, Anthony E; Klocke, Carolyn R; Silverman, Jill L; Puschner, Birgit; Pessah, Isaac N; Lein, Pamela J
Human
发育与干细胞
神经科学
发表日期：2021
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