日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Expression of receptor-type protein tyrosine phosphatase in developing and adult renal vasculature

发育中和成年肾血管中受体型蛋白酪氨酸磷酸酶的表达

Takahashi, Keiko; Kim, Rachel; Lauhan, Colette; Park, Yuna; Nguyen, Nghiep G; Vestweber, Dietmar; Dominguez, Melissa G; Valenzuela, David M; Murphy, Andrew J; Yancopoulos, George D; Gale, Nicholas W; Takahashi, Takamune

Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations

由于逃逸突变占主导地位,需要广泛的CTL反应才能清除潜伏的HIV-1。

Deng, Kai; Pertea, Mihaela; Rongvaux, Anthony; Wang, Leyao; Durand, Christine M; Ghiaur, Gabriel; Lai, Jun; McHugh, Holly L; Hao, Haiping; Zhang, Hao; Margolick, Joseph B; Gurer, Cagan; Murphy, Andrew J; Valenzuela, David M; Yancopoulos, George D; Deeks, Steven G; Strowig, Till; Kumar, Priti; Siliciano, Janet D; Salzberg, Steven L; Flavell, Richard A; Shan, Liang; Siliciano, Robert F

Cleft Palate, Moderate Lung Developmental Retardation and Early Postnatal Lethality in Mice Deficient in the Kir7.1 Inwardly Rectifying K+ Channel

Kir7.1 内向整流钾离子通道缺陷小鼠出现腭裂、中度肺发育迟缓和早期出生后死亡

Villanueva, Sandra; Burgos, Johanna; López-Cayuqueo, Karen I; Lai, Ka-Man Venus; Valenzuela, David M; Cid, L Pablo; Sepúlveda, Francisco V

Precise and in situ genetic humanization of 6 Mb of mouse immunoglobulin genes

对6 Mb小鼠免疫球蛋白基因进行精确的原位基因人源化

Macdonald, Lynn E; Karow, Margaret; Stevens, Sean; Auerbach, Wojtek; Poueymirou, William T; Yasenchak, Jason; Frendewey, David; Valenzuela, David M; Giallourakis, Cosmas C; Alt, Frederick W; Yancopoulos, George D; Murphy, Andrew J

Mice with megabase humanization of their immunoglobulin genes generate antibodies as efficiently as normal mice

免疫球蛋白基因经过兆碱基人源化改造的小鼠,其产生抗体的效率与正常小鼠一样高。

Murphy, Andrew J; Macdonald, Lynn E; Stevens, Sean; Karow, Margaret; Dore, Anthony T; Pobursky, Kevin; Huang, Tammy T; Poueymirou, William T; Esau, Lakeisha; Meola, Melissa; Mikulka, Warren; Krueger, Pamela; Fairhurst, Jeanette; Valenzuela, David M; Papadopoulos, Nicholas; Yancopoulos, George D

IL-22 promotes fibroblast-mediated wound repair in the skin.

IL-22促进皮肤中成纤维细胞介导的伤口修复

McGee Heather M, Schmidt Barbara A, Booth Carmen J, Yancopoulos George D, Valenzuela David M, Murphy Andrew J, Stevens Sean, Flavell Richard A, Horsley Valerie

IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine

IL-22BP受炎症小体调控,并调节肠道肿瘤的发生。

Huber, Samuel; Gagliani, Nicola; Zenewicz, Lauren A; Huber, Francis J; Bosurgi, Lidia; Hu, Bo; Hedl, Matija; Zhang, Wei; O'Connor, William Jr; Murphy, Andrew J; Valenzuela, David M; Yancopoulos, George D; Booth, Carmen J; Cho, Judy H; Ouyang, Wenjun; Abraham, Clara; Flavell, Richard A

Atypical angiopoietin-like protein that regulates ANGPTL3

调节 ANGPTL3 的非典型血管生成素样蛋白

Quagliarini, Fabiana; Wang, Yan; Kozlitina, Julia; Grishin, Nick V; Hyde, Rhonda; Boerwinkle, Eric; Valenzuela, David M; Murphy, Andrew J; Cohen, Jonathan C; Hobbs, Helen H

Mice completely lacking immunoproteasomes show major changes in antigen presentation

完全缺乏免疫蛋白酶体的小鼠表现出抗原呈递的显著变化。

Kincaid, Eleanor Z; Che, Jenny W; York, Ian; Escobar, Hernando; Reyes-Vargas, Eduardo; Delgado, Julio C; Welsh, Raymond M; Karow, Margaret L; Murphy, Andrew J; Valenzuela, David M; Yancopoulos, George D; Rock, Kenneth L

Human thrombopoietin knockin mice efficiently support human hematopoiesis in vivo

人血小板生成素敲入小鼠可在体内有效支持人类造血功能。

Rongvaux, Anthony; Willinger, Tim; Takizawa, Hitoshi; Rathinam, Chozhavendan; Auerbach, Wojtek; Murphy, Andrew J; Valenzuela, David M; Yancopoulos, George D; Eynon, Elizabeth E; Stevens, Sean; Manz, Markus G; Flavell, Richard A