日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Further Probing the Properties of a Unique Sponge-derived Alkaloid Through the Isolation of a New (-)-(5E)-(8R)-(14Z)-Mycothiazole Analogue

通过分离一种新的(-)-(5E)-(8R)-(14Z)-霉噻唑类似物,进一步探究一种独特的海绵来源生物碱的性质

Gerke, Joe A; Odron, Sofia F; Kim, Juri; Dutta, Naibedya; Clarke, Jacqueline G; Media, Joseph; Coppage, David A; Oorloff, Maria; Alcala, Athena; Garcia, Gilberto; Kang, Marissa E F; Gerke, Cy L; Peterson, Jacob C; Morris, Joseph D; Higuchi-Sanabria, Ryo; Valeriote, Frederick A; Crews, Phillip; Johnson, Tyler A

A Versatile Chemoenzymatic Synthesis for the Discovery of Potent Cryptophycin Analogs

一种用于发现高效隐藻素类似物的多功能化学酶法合成

Schmidt, Jennifer J; Khatri, Yogan; Brody, Scott I; Zhu, Catherine; Pietraszkiewicz, Halina; Valeriote, Frederick A; Sherman, David H

Computationally Assisted Discovery and Assignment of a Highly Strained and PANC-1 Selective Alkaloid from Alaska's Deep Ocean

利用计算机辅助方法发现并鉴定阿拉斯加深海中一种高应变且对PANC-1具有选择性的生物碱

Zou, Yike; Wang, Xiaojuan; Sims, James; Wang, Bin; Pandey, Pankaj; Welsh, Colin L; Stone, Robert P; Avery, Mitchell A; Doerksen, Robert J; Ferreira, Daneel; Anklin, Clemens; Valeriote, Frederick A; Kelly, Michelle; Hamann, Mark T

Computationally Assisted Assignment of the Kadsuraols, a Class of Chemopreventive Agents for the Control of Liver Cancer.

利用计算机辅助方法确定卡苏拉醇类化合物(一类用于控制肝癌的化学预防剂)的用途

Wang Xiaojuan, Liu Jiabao, Pandey Pankaj, Fronczek Frank R, Doerksen Robert J, Chen Jiabao, Qi Xinzhu, Zhang Peicheng, Ferreira Daneel, Valeriote Frederick A, Sun Hua, Li Shuai, Hamann Mark T

The potential of achiral sponge-derived and synthetic bromoindoles as selective cytotoxins against PANC-1 tumor cells

非手性海绵衍生和合成溴吲哚作为针对PANC-1肿瘤细胞的选择性细胞毒素的潜力

Lorig-Roach, Nicholas; Hamkins-Indik, Frances; Johnson, Tyler A; Tenney, Karen; Valeriote, Frederick A; Crews, Phillip

Integrating Molecular Networking and Biological Assays To Target the Isolation of a Cytotoxic Cyclic Octapeptide, Samoamide A, from an American Samoan Marine Cyanobacterium

整合分子网络和生物学检测方法,以从美属萨摩亚海洋蓝藻中分离细胞毒性环状八肽萨摩酰胺A。

Naman, C Benjamin; Rattan, Ramandeep; Nikoulina, Svetlana E; Lee, John; Miller, Bailey W; Moss, Nathan A; Armstrong, Lorene; Boudreau, Paul D; Debonsi, Hosana M; Valeriote, Frederick A; Dorrestein, Pieter C; Gerwick, William H

Cytotoxic halogenated monoterpenes from Plocamium cartilagineum

来自软骨假单萜的细胞毒性卤代单萜

Sabry, Omar M M; Goeger, Douglas E; Valeriote, Frederick A; Gerwick, William H

Kalkitoxin inhibits angiogenesis, disrupts cellular hypoxic signaling, and blocks mitochondrial electron transport in tumor cells

卡尔基毒素抑制血管生成,破坏细胞缺氧信号传导,并阻断肿瘤细胞中的线粒体电子传递。

Morgan, J Brian; Liu, Yang; Coothankandaswamy, Veena; Mahdi, Fakhri; Jekabsons, Mika B; Gerwick, William H; Valeriote, Frederick A; Zhou, Yu-Dong; Nagle, Dale G

An efficient and cost-effective approach to kahalalide F N-terminal modifications using a nuisance algal bloom of Bryopsis pennata

利用羽状羽藻(Bryopsis pennata)这种有害藻类水华,对卡哈拉利德F的N端进行高效且经济的修饰。

Wang, Bin; Waters, Amanda L; Valeriote, Frederick A; Hamann, Mark T

Enantioselective divergent syntheses of several polyhalogenated Plocamium monoterpenes and evaluation of their selectivity for solid tumors

几种多卤代 Plocamium 单萜的对映选择性发散合成及其对实体瘤选择性的评价

Vogel, Carl V; Pietraszkiewicz, Halina; Sabry, Omar M; Gerwick, William H; Valeriote, Frederick A; Vanderwal, Christopher D